Christopher A. Baker @bakermind
Firstgen in Yale Center for Infection & Immunity using imaging technologies to study pain in long COVID and similar syndromes. https://t.co/Dhf7B783IT JP➡️TX➡️PI➡️OH➡️CT➡️FL➡️WA➡️CT Joined October 2012-
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@Illusionist999 @TaylorLorenz @WIRED Yeah there is snake oil in this space, just like there is in the neutraceutical space. You can never blame a patient when a "therapeutic" approach doesn't work
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@RealCheckMarker @amymitchellart I never said that pharmacology isn't the right therapy, I only said that neuropharmacology and neurophysiology are therapies just like JAK/STAT inhibitors and IVIG. Nothing is off the table when it comes to helping people
I'm excited to share my first full research article as coauthor with @keylas3 @VirusesImmunity et al @YaleCII, on autoantibodies from long COVID patients being sufficient to elicit pathology and symptoms upon transfer to mice (link free til July 17) 1/ sciencedirect.com/science/articl…
@uht_fresh @NotOstriching Yes there are going to be people selling mind-body snake oil, but my point is that I don't care if a therapy works on macrophages or neurons, as long as it helps the patient. northwell.edu/news/the-lates…
@baroque_bitch Nah the better tech might be vagal nerve stimulation, which is cleared for use in RA. But until then we're working on old fashioned autoantibody mediated mechanisms kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…
@Zedzies @AlanLevinovitz @amymitchellart @WIRED The wishful thinking concept is ripe for poor exploitation, but it can also elicit effects that deserve further study. Perhaps the biofeedback study from Nature Medicine was mentioned (wired article is paywalled), but there's also this experiment nature.com/articles/s4159…
@RealCheckMarker @Zedzies @amymitchellart @AlanLevinovitz @WIRED ... whereas those nerves act on skin macrophages to LIMIT cancer. We're only beginning to discover the interplay between the nervous and immune systems. 2/2 cell.com/neuron/fulltex…
@RealCheckMarker @Zedzies @amymitchellart @AlanLevinovitz @WIRED I use that paper just as an example that the nervous system can control the immune system. Such things are rarely unidirectional. Indeed, nerve stimulation affects macrophages in the lung to promote cancer... 1/2 sciencedirect.com/science/articl…
@Zedzies @amymitchellart @AlanLevinovitz @WIRED Yes it is unfortunate that there will be scammers entering this space, promoting "mind training" or even "neural stimulators" without rigor as a cure, just like others promote "peptides". But if we test RIGOROUSLY, then we should consider all interventions even if above the neck
@Riginal_Zen @frogess33 You're speaking to a person who has actually done these experiments. I'm just pointing out the limitations of the methods used by both them and us. The animal model is not going to demonstrate the same things a patient experiences kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…
@Zedzies @amymitchellart @AlanLevinovitz @WIRED I don't believe in the word psychosomatic. But if we identify brain circuits that augment macrophages to selectively clear virus, so be it
It's pleasure and privilege to work with such a team of talented individuals crossing many disciplines to seek solutions to a looming and underappreciated problem of chronic disease after infection. I can't do a better tweetorial than our leader, so: x.com/i/status/20600…
Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab doi.org/10.1016/j.cell…
@internetuserf12 @bhanlon15 there are likely a lot of disingenuous actors in this space, but the nervous system can control the immune system, and we should find ways to leverage that. Already vagal implants are approved for autoimmune disorders. cell.com/cell/fulltext/…
@amymitchellart @AlanLevinovitz @WIRED I dunno, nervous system activity is sufficient to alter B cells development. One problem is framing: we should amplify how cutting edge it is to explore brain control of immunity and perhaps harness that with technology. cell.com/cell/fulltext/…
@TaylorLorenz @WIRED Do you not think the brain is a biological organ? Do you know that vagus nerve stimulation is approved for rheumatoid arthritis? Do you not know that brain activity is sufficient to control the immune system? I do understand the LC community is averse because of gaslighting tho
@EndTribalism Alpha Gal syndrome is hurting his push for the use of beef tallowand consumption of mammalian meat
@HorsesGraz84310 @EndTribalism Not just red meat: can be any mammalian product. RFK loves beef tallow. Cheese, milk, pork, (bovine) gelatin in food or pills or cosmetics could be trouble
@ZdenekVrozina In a patient with long COVID, self reactivity is continuously produced. With a transfusion, any transferred IgG will have a finite lifespan. It's not the same as transferring an infectious agent that can replicate. But we can consider additional safeguards for donated blood
Marina Picciotto @MarinaP63
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allen institute @AllenInstitute
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Kording Lab 🦖 @KordingLab
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Sebastian S. Cocioba�... @ATinyGreenCell
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CoronaZero simongehre... @CoronaZeroCH
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73K Followers 13K Following I science & try to make science open. Tweets do not represent my employer's views, but are always correct. My conflicts of interest https://t.co/77P0LDe6VR.
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mightymoose at the bl... @Moose4Science
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S Blitshteyn MD, FAAN... @dysclinic
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87 Followers 56 Following Pediatric infectious disease doctor @YaleMed. Researching #LongCOVID in children. Caring for kids with post-acute infection syndromes.
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Ryan Rhodes ⚙️�... @langofmind
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879 Followers 649 Following Postdoc immunologist with @EJohnWherry at Penn, studying immune responses to SARS-CoV-2, viral infections, Long COVID, and beyond
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