harmon @_harm0n
building in biosecurity | prev @wisconsincs @securebio @mit harm0n.com New York Joined May 2021-
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Happy to announce that our first sequencing service -- SPLICE -- is now generally available. For decades, transcriptomics has focused on gene-level analysis, but we know that most human genes undergo alternative splicing -- emitting different mRNA variants that can have completely different functions. The collapse to gene-level analysis keeps the set of therapeutic targets smaller than it has to be. The focus on genes is partially due to the difficulty of reconstructing splicing patterns from short read sequencing data, and partially due to the difficulty of effectively using long reads to capture full-length RNA molecules. Today, we release SPLICE to make full-length RNA sequencing easy and systematic -- opening up a larger set of candidate targets to everyone. Some key benefits of our service: both bulk and single-cell modes, no sample minimums, turnaround in under a week, no bioinformatician needed, full access to our data management and analysis suite, and 4x more reads per cell than what is typically found in the literature. Further, one untargeted assay gives you expression, V(D)J recombinations, whole exome variants, and splicing information. It's a very high yield assay for samples that are often extremely precious. We're also releasing updates to our tools. Shown below are queries we've added to our genomics viewer for comparing canonical isoforms against other variants and for finding reads that capture both 5' and 3' ends. The data shown is real data generated from our service -- we have example data readily available. We've been running SPLICE privately with rare disease customers for months and are happy to finally make it generally available.
Hey everyone! We want to build a biosecurity community in NYC, and we're going to be running our first social in Manhattan on April 30. Come meet other people working on or thinking about biosecurity, and enjoy some food and drinks. Newcomers welcome! No biosecurity experience needed.
Announcing our $60M raise today. We're scaling Perimeter to accelerate the next era of biosecurity. Building detection and response infrastructure for the current and next era of biological threats. Excited to partner with Kanders & Co, Goldcrest Capital, SCS Financial, Four Cities Capital, and the AI Safety Fund (SAIF). prnewswire.com/news-releases/…
I love lab robotics. I also hate AI in bio that has ZERO validation. Wouldn’t it be cool if we could use robots to autonomously do REAL experiments? Im makin a cloud lab that doesn’t suck. Low capex, starting small, but making it god damn useful and god damn programmable
New (working) paper: AI Scientist via Synthetic Task Scaling We have seen the first sparks of automated AI research done by LLMs, but how do we train them to be better auto-researchers?
@davidkmyang also want to know this answer, i wasn't able to find any resources on this online
@owl_posting also going to tag some old co-workers, @seth_donoughe @Simon__Grimm
@owl_posting i'm working on a biosecurity startup in this space, i'd be happy to chat. i've also written a bit about this, x.com/_harm0n/status….
Ever wonder how you could use your computer science skills to stop the next pandemic, but don't know where to start. In a new post, I provide an introduction into viral biosurveillance and the computational problems that come with it.
We ran a randomized controlled trial to see if LLMs can help novices perform molecular biology in a wet-lab. The results: LLMs may help in some aspects, but we found no significant increase at the core tasks end-to-end. That's lower than what experts predicted. Our findings 🧵
@prerat once you get to a high enough level though, everyone knows the common openings
@prerat this is why i learned the english, got me pretty far, but i'd always get destroyed by the maroczy bind
some people that can probably give you feedback is your advisors
one the benefits of working at a company is that you can get mentorship/feedback from more tenured individuals on how you can better work. however, when you're founding a startup with some of your peers, it's unlikely you'll have that same senior experience. does anyone have any advice on this or any articles that have been written on this?
@bubbleboi oops i clearly did not watch the whole video, and just jumped straight to the site
this is cool
anyone want to play chess at neurips #neurips25
Achyut Reddy @achyutr24
75 Followers 818 Following
Joshua Teperowski Mon... @jtmonrad
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Surag Nair @suragnair
1K Followers 704 Following Machine learning and genetics @Genentech. Previously CS PhD @Stanford.
n/a @foolishmasei
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Faisal AlZaben • ف... @polymorfaisal
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Nnadi Nnaemeka @NnaemekaNnadi
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Riya Bisht @b1shtream
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John Kitaoka @johnkitaoka
85 Followers 525 Following Research fellow @matsprogram, prev AI @awscloud, views my own!
James @basedsystems
643 Followers 185 Following cofounder @hoxbio | building integrated systems for discovery, health, and security
Patrick Malone, MD Ph... @patricksmalone
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Mackenzie Morehead @mackenziejem
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Kamal Maher @fluorocore
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owl @owl_posting
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Nish @nterminus
2K Followers 2K Following Now: biology investing @ https://t.co/Fmj3dMHPe7 Then: @Color | @SciFounders
Hannu Rajaniemi @hannu
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Lakshmi Miller-Vedam @shelakshmenot
1K Followers 7K Following Drug Discovery Sculptor at Fathom Tx formerly @ Relay Tx, MIT, UCSF. Science, deep tech, AI x bio, cell bio, protein engineering, biophysics, & structural bio.
Seth Donoughe @seth_donoughe
2K Followers 864 Following AIxBio research scientist, working to make sure new tech makes the world better. Director of AI at SecureBio.
Logan Graham @logangraham
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Jeannie She @jeannieshe_
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Sothay @Sothay256790
43 Followers 277 Following I thought love that comes in time is the best love, but it is not a patch on your love at first sight
Rev Industry @ROI_RevIndustry
34 Followers 295 Following you wouldn’t hear it if they were shooting at me with howitzers
Tommy Crow 🏗️ @TommyJoanCrow
170 Followers 484 Following First documented person to get modern FTM top surgery fully awake. I like surgery, abundance, classical liberalism(≠centrism), gay male culture, & big machines
Li @YungNika10
0 Followers 9 Following Living with intention, loving with depth, and growing with grace.
anaum @anaumghori
1K Followers 490 Following
Elizabeth Wood 🧬�... @lizbwood
2K Followers 3K Following Founder and CEO at @JURA_bio. Copenhagen | Boston | Basel | Oslo https://t.co/cgjeyYq1Fr
Stephen Turner 🦋 @... @strnr
31K Followers 621 Following I'm no longer posting from this account. Find me elsewhere: Bluesky: https://t.co/MmU0tLyeHd Newsletter: https://t.co/qGepdBtVme
Narutatsu Ri @narutatsuri
453 Followers 336 Following PhD Student @PrincetonPLI. Previously BS @Columbia
Rajat V D @rajat_vd
366 Followers 285 Following ICME PhD Student at @Stanford. Previously EE undergrad @iitmadras. Blog: https://t.co/fyf4HbKLjv
Carolin Reges @CarolinReg77016
0 Followers 58 Following
Hilda Baires @BairesHild10513
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Zachary Kurtz @ledflyd
595 Followers 1K Following comp bio PhD @Perimeter. Following rationalists, biotech entrepreneurs, scientists, researchers, designers & craft brewers.
Jeremy @jeremypyang
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Burian @Burian623408
1 Followers 119 Following
Shifu @NichitShivam
50 Followers 426 Following Aspiring Computational Biologist, final year at DYPU | Football player et Cinephile
Rene @Rene274734
0 Followers 97 Following
Egon @Egon1615632
1 Followers 116 Following
Felicity @RKertzmann10258
207 Followers 7K Following
Joshua Teperowski Mon... @jtmonrad
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Matt Pocock @mattpocockuk
283K Followers 784 Following I teach devs for a living. Author of Total TypeScript and AI Hero. Ex-@vercel. Used to be a voice coach.
levent @__alpoge__
4K Followers 99 Following idiot. cuda og, harvard val, morgan prize, society of fellows, 1 hilbert problem so far, creating friendly, SAFE, delightful, supergenius ..things @anthropicai
Thomas Ballinger @ballingt
4K Followers 866 Following @anthropicai prev @convex_dev @observablehq @dropbox @recursecenter
Lauren Pearson @laurenap_
2K Followers 4K Following neurobio research @uvic | biosec @pilgrimlabs | cog. cartography @mit_csail (kellis lab) | prev. HCI/BCI research @terctweets
Surag Nair @suragnair
1K Followers 704 Following Machine learning and genetics @Genentech. Previously CS PhD @Stanford.
Jiaxin Wen @jiaxinwen22
6K Followers 192 Following research @berkeley_ai @anthropicai. prev @tsinghua_univ.
Faisal AlZaben • ف... @polymorfaisal
236 Followers 981 Following 🧬• 🧫 • 🇵🇸 Berkeley MCB '20 ➡ Extavour Lab @ Harvard ➡ Exciting things in bio🧬AI... evolution, AI, genetics, microbio, and everything in between
Brian Huang @brianryhuang
6K Followers 2K Following @GoogleDeepmind @antigravity | prev math and cs @mit
Helium @heliumbrowser
20K Followers 1 Following Privacy-first browser with unbiased ad-blocking and a clean, minimal interface. Browse the web without noise. Fully open source, by @imputnet
(((ل()(ل() 'yoav)))... @yoavgo
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Patrick C Toulme @PatrickToulme
3K Followers 217 Following TPU/XLA @google. Formerly worked on Meta MTIA and AWS Trainium. Opinions are my own. All blogs shared are personal work.
Adam Mainz @MainzOnX
3K Followers 147 Following PyTorch TPU @google | ex @meta | Obsessed with AI & ML Performance | Building what’s next 🔥 | Views are my own
Seth Howes @SethSHowes
8K Followers 767 Following 🩺 doctor defected to tech 👨🏼💻 prev engineer @exolabs | medicine @uniofoxford | ML @imperialcollege
Riya Bisht @b1shtream
1K Followers 5K Following accelerating biology using AI/computing @join_ef, neuromorphic @CeNSEatIISc, VC @Lvlupvc, @iiscbangalore,prev @Vicharak_In @CERN @BerkeleyLab, @ucberkeley
JM Rothberg @JMRothberg
13K Followers 900 Following Fast (Next-Gen) DNA sequencing, Ultrasound-on-a-Chip, Portable MRI, Next-Gen Protein Sequencing, POC Diagnostics, Retinal Scanner. [email protected]🧬
John Kitaoka @johnkitaoka
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Serena Wang @swang_co
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Sam Hall @Shmall
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Chris Meserole @chrismeserole
3K Followers 740 Following Executive Director, Frontier Model Forum | Former Director, Brookings A.I. & Emerging Tech Initiative
David R. MacIver @DRMacIver
8K Followers 557 Following What's for breakfast? Onward! Towards the abyss. @[email protected] if you want a backup, but I don't toot there yet.
Wojciech Zaremba @woj_zaremba
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gian @giansegato
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Olivia H. Scharfman @OliviaHelenS
4K Followers 3K Following Biosecurity & Biotechnology @IFP. Formerly: Co-founder @ LincSwitch Tx, Principal @ SALT Fund, Biophysics @Yale, Chairman @SEDSusa, @XPRIZE.
Kamal Maher @fluorocore
230 Followers 803 Following AI agents, interpretability, and biology @mit @cornell @sparexec
The Consensus @theconsensusdev
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Spencer Macdonald @spencermac_
2K Followers 2K Following "You wanna know how I did it? This is how I did it, Anton. I never saved anything for the swim back."
Owen Oertell @owenoertell
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Zaixi Zhang @ZaixiZhang
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Marc Johnson @SolidEvidence
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Matthew F. McKnight @matt_f_mcknight
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