Total Synthesis and Methodology Highlights @TotalSyntheses
Highlight Total Synthesis, Organometallic Chemistry, Heterocycles Synthesis, Biosynthesis, Medicinal Chemistry, Electrochemistry and Photochemistry. United States Joined December 2016-
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Concise Synthesis of (−)-GA18 Methyl Ester @MingjiDai @LifeAtPurdue @EmoryChem @EmoryUniversity @TotalSyntheses @TotalSynthesis #Synthesis #2plus2 #Transhydrindane #Gibberellins pubs.acs.org/doi/10.1021/ja…
Asymmetric Total Synthesis of Havellockate pubs.acs.org/doi/10.1021/ja…
Excited-State Copper-Catalyzed [4 + 1] Annulation Reaction Enables Modular Synthesis of α,β-Unsaturated-γ-Lactams @SUNY @TotalSyntheses #Cu #ExcitedState #Annulation #Modular #Lactams #Enamides pubs.acs.org/doi/10.1021/ja…
Check out our recent syntheses of bufospirostenin A and ophiopogonol A in only seven steps from inexpensive starting materials just out in @J_A_C_S . Great collaboration with Hong group from Zhejiang University for computational studies: pubs.acs.org/doi/10.1021/ja…
JACS online： #Symmetry-Driven Total #Synthesis of #Myrioneurinol @J_A_C_S @isciverse @CHNSci @UTSWNews @TotalSynthesis @TotalSyntheses #Chemistry #Science #Catalysis #technology pubs.acs.org/doi/10.1021/ja…
Synthesis of Pleuromutilin @UCIChemistry @UCIrvine @TotalSynthesis @TotalSyntheses #Pleuromutilin #Total #Synthesis pubs.acs.org/doi/10.1021/ja…
JACS online: Asymmetric Total #Syntheses of #Cephalotane-Type #Diterpenoids #Cephanolides A–D @J_A_C_S @isciverse @CHNSci @PKU1898 @TJU1895 @TotalSynthesis @TotalSyntheses #Chemistry #Science #Catalysis #technology pubs.acs.org/doi/10.1021/ja…
Introducing the Catalytic Amination of Silanes via Nitrene Insertion @PedroJPerez65 @CIQSO_UHU @MaserasGroup @ICIQchem @_BIST #Catalytic #Amination #Silanes #Nitrene @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers @ListLaboratory @ben_list @ICReDDconnect #Organocatalysis @TotalSyntheses #Silyl #Stereogenic #Silylethers pubs.acs.org/doi/10.1021/ja…
Happy to report a practical bottom-up synthesis of aminoglycoside antibiotic ribostamycin!!! Collaborative efforts with @pengliu_group. Novel asymmetric catalytic desymmetrization of ⌬ (♡!), mechanism, com. studies, and more! nature.com/articles/s4416…
Ever wondered about directly turning the indole skeleton of a bioactive compound into a quinazoline or quinoxaline by "just" inserting a N atom? Check this MS @ChemRxiv from Julia, @origree1, @HappyFranchino, @PDFinkelstein. doi.org/10.26434/chemr…
Cu-Mediated Ullmann-Type Cross-Coupling and Industrial Applications in Route Design, Process Development, and Scale-up of Pharmaceutical and Agrochemical Processes pubs.acs.org/doi/10.1021/ac…
Two-Stage Syntheses of Clionastatins A and B @CHNSci @TotalSynthesis @TotalSyntheses #Synthesis #Clionastatins #Chlorination pubs.acs.org/doi/10.1021/ja…
Synthesis of Dimeric Securinega Alkaloid Flueggeacosine B: From Pd-Catalyzed Cross-Coupling to Cu-Catalyzed Cross-Dehydrogenative Coupling @kaist #TotalSynthesis @TotalSynthesis @TotalSyntheses #Alkaloid #Pd #CrossCoupling #Cu #Dehydrogenative pubs.acs.org/doi/10.1021/ja…
Versatile Palladium-Catalyzed Approach to Acyl Fluorides and Carbonylations by Combining Visible Light- and Ligand-Driven Operations @mcgillu @TotalSyntheses #Palladium #Fluorides #Light pubs.acs.org/doi/10.1021/ja…
Remembering Professor Tomáš Hudlický | brocku.ca/brock-news/202… #brocku
Design of an Organocatalytic Asymmetric (4 + 3) Cycloaddition of 2-Indolylalcohols with Dienolsilanes @ben_list @ListLaboratory @MPI @TotalSyntheses #Organocatalysis #Asymmetric #indole #Cycloaddition #Dienolsilanes pubs.acs.org/doi/10.1021/ja…
A Unified Approach to Decarboxylative Halogenation of (Hetero)aryl Carboxylic Acids @dmac68 @MacMillan_Lab @PrincetonChem @TotalSyntheses @pfizer_news @NCState @NCStateChem @CastellanoGroup @FNCastellano #decarboxylative #Halogenation #Hetaranes pubs.acs.org/doi/10.1021/ja…
Breaking news courtesy of Kevin Campos and Dave MacMillan, from Sally Evans. Dave passed away last night. This pic that they included is how Dave looked during my days in his group. Circa 1985-87
Been waiting for this one to come out - photochem conversion of broad HetAr-CO2H monomer set to halides - really neat work out in @J_A_C_S Asap from @CastellanoGroup @NCStateChem @MacMillan_Lab and #PfizerChemistry @AnneMar09355251 #ChemCollabs doi.org/10.1021/jacs.2…
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Potassium trifluoroborates are an excellent choice for thermal and photochemical C-C, C-N, and C-O cross-coupling transformations. Enamine offers a collection of 413 aliphatic trifluoroborates. Download sdf here: bit.ly/46oSzII
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I mean. Postdoc at NIH pay ~55k Postdoc at National Lab ~70-90k Industry ~90k ++++ And the most important part, the odds of landing a faculty job these days are incredibly low.
چند تا توصیه که اگه به عقب برگردم واسه خودم دارم: ۱. گاهی کمتر کار کردن ما رو نزدیک تر میکنه به موفقیت. مهمترین ثروتمون وقته و خیلی وقتا به جای استفاده درست ازش، با چیزای مختلف پرش میکنیم و فرصت کارهای مفیدتر و کم هزینه تر رو از خودمون میگیریم
@DavePalmerUSask @DrLCsquare I am an outsider too. But this might help. Maybe not the level of precision you seek, but FWIW I think it is useful to know that about ~3% of petrochemicals funnel to pharma and >99% of API content is petroleum derived.
(15) Work on the hard stuff if you want to get better.
(12) The better your teammates, the better you are.
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