Tom Snelling @TWSnelling
Postdoc with Philip Cohen @mrcppu @dundeeuni with an interest in cell signalling and rare diseases! linkedin.com/in/tom-snellin… Dundee Joined February 2019-
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Tom Snelling retweeted
Available online - the Review "Diseases caused by altered specificity of a #proteinkinase for its allosteric activators" from Philip Cohen and @TWSnelling @mrcppu @dundeeuni. #AtypicalAlphaKinase #ALPK1 #ROSAHsyndrom #Spiradenoma authors.elsevier.com/sd/article/S09…
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Tom Snelling retweeted
Quantitative Measurement of the Kinase Activity of Wildtype ALPK1 and Disease-Causing ALPK1 Mutants Using Cell-Free Radiometric Phosphorylation Assays: bio-protocol.org/en/bpdetail?id… Work by @TWSnelling at the @dundeeuni. #Reproducibility #LifeSciences #Biochemistry
Tom Snelling retweeted
Multimodal scanning of genetic variants with base and prime editing go.nature.com/3O6wQ0O
Tom Snelling retweeted
How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer? A new role for an autophagy receptor IRGQ in this process with a clinical relevance for the development of liver carcinoma in humans and mice 😊😀 sciencedirect.com/science/articl…
Tom Snelling retweeted
Now open – a CRUK-funded PhD clinical research training fellowship in my team at the Wellcome Sanger Institute. crukcambridgecentre.org.uk/education-and-…
Tom Snelling retweeted
JOB ALERT! MND Accelerator Award funded postdoctoral position in my lab @mrcppu is now LIVE. We will use pooled CRISPR screening of iPSC motor neurons to identify new targets for ALS/MND. To learn more & apply: ppu.mrc.ac.uk/careers/recrui… Please help spread the word! Thank you.
Happy to share two protocols describing how to study #ALPK1 disease-causing variants using cell-based and cell-free kinase assays! They were used in our recent preprint on #ROSAH syndrome. (doi.org/10.1101/2024.0…) doi.org/10.21769/BioPr… doi.org/10.21769/BioPr… #UoDLifeSciences
Tom Snelling retweeted
Delighted to share our work in @NatureGenet using base editing to map genetic mechanisms of drug resistance. If you're interested in drug discovery then check it out. Access here rdcu.be/dXmlo [rdcu.be]. Congratulations to the team and @MatthewACoelho
Today we report in @NatureGenet the genetic landscape of cancer drug resistance mechanisms from CRISPR base editing screens nature.com/articles/s4158…
Tom Snelling retweeted
Congrats to Celest Tay @taycell & Oliwia Mruk @olimruk who received Highly Commended Awards in the Life Science category of the Global @UndergradAward 2024. This was in recognition of their honours project research which both undertook @mrcppu buff.ly/4e8dIuI
Excited to share our preprint reporting on the discovery of a new ALPK1 variant causing ROSAH syndrome in a family with 7 affected members! We also characterise this variant, showing its constitutive activity in cells #ROSAH #ALPK1 #mrcppu #UoDLifeSciences biorxiv.org/content/10.110…
@Dr_Ian_Kelsall Thanks Ian, hope you are doing well!
Tom Snelling retweeted
Congratulations Elisha and Catriona: Professor Sir Philip Cohen's 50th and 51st PhD students awarded their degress ppu.mrc.ac.uk/news/elisha-an… @elishamccrory_ @catriona_aitken
Tom Snelling retweeted
An excellent postdoctoral opportunity to join @sapkota_mrcppu to work on WNT signalling and colorectal cancer. We are looking for someone with a with a strong background in cell and molecular biology. To apply: jobs.ac.uk/job/DGS778/pos… @mrcppu @UoDLifeSciences @dundeeuni
@DrTomTORC @UoDLifeSciences @BiochemSoc @OyieJessica @mrcppu Thank you! 😀
Tom Snelling retweeted
Congratulations to @TWSnelling and @OyieJessica for receiving International Sponsored Places to attend the Biomolecular Horizons Congress 2024! We can't wait to hear about their experiences at this global forum celebrating the latest developments in bioscience and biotechnology.
Tom Snelling retweeted
To restore cellular homeostasis, stress responses should be turned off at the right time and place. A paper @Nature shows a ubiquitin-dependent mechanism through which unimported mitochondrial proteins silence the integrated stress response. nature.com/articles/s4158…
Thrilled to have been awarded the Howard Elder Prize for my work on ALPK1😃. This kinase is activated by bacterial ADP-heptose, but mutations that cause a genetic disease and a rare cancer allow it to also be activated by human metabolites! #ALPK1 @mrcppu @UoDLifeSciences
Tom Snelling retweeted
📢 Are you interested in joining our lab in Copenhagen🇩🇰 as a #postdoc? We are an ambitious and friendly research group 👩🔬👨🔬 working on the regulation of #metabolism and #inflammation by #ubiquitin 🔬🧬. Project details and application link below👇 Please share!
MRC PPU @mrcppu
3K Followers 1K Following The MRC Protein Phosphorylation & Ubiquitylation Unit is a world leader in finding the causes of neurodegeneration, cancer, hypertension & immune disorders
UoD Life Sciences @UoDLifeSciences
5K Followers 763 Following School of Life Sciences at the University of Dundee @dundeeuni Top University in the UK for Biological Sciences - Research Excellence Framework 2021
Mahima Swamy @MahimaSwamy
1K Followers 712 Following Immunologist @dundeeuni @mrcppu interested in all aspects of the gut, strong interest in gender equality and diversity in STEM (she/her)
Bill Carton @CartonBill
355 Followers 483 Following Senior Scientist at @PneumagenLtd working on respiratory tract infections. Former PhD student @sapkota_mrcppu @mrcppu.
Sven Lange @Sven_M_Lange
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Ian Kelsall @Dr_Ian_Kelsall
466 Followers 429 Following Senior Research Associate @mrcppu, working in the lab of @YKulathu. Interested in ubiquitin, RBR ligases, innate immune signalling and heavy metal 🤘
Elisha McCrory @elishamccrory_
499 Followers 369 Following @WellcomeTrust funded PhD Student in the lab of Prof. Sir Philip Cohen at the MRC PPU 🇯🇵🌸 she/her
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Trends in Biochemical... @TrendsBiochem
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María Rodríguez-Rí... @MariaRRios3
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Australasian Genomic ... @agtaGenomics
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jake @mediocre_jake
64 Followers 177 Following 🇲🇾Postdoc WEHI @FelthamLab PhD @BrownLabUNSW #ubiquitin #inflammation #cholesterol 🆕️ 2024 account, past account was deleted - keen to reconnect
Dr Genevieve Syn @GenevieveSyn
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Nils Birkholz @NilsBirkholz
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Dorothea Boeken @DorotheaBoeken
106 Followers 196 Following PhD student working on tau in the @KlenermanLab, @UKDRI
Jonathan Breiter @JCBreiter
170 Followers 752 Following PhD Student in Neuroscience @Cambridge_uni Researching Parkinson's Disease using fluorescence microscopy as part of @PD_BrainMap & @ASAP_Research
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MRC PPU @mrcppu
3K Followers 1K Following The MRC Protein Phosphorylation & Ubiquitylation Unit is a world leader in finding the causes of neurodegeneration, cancer, hypertension & immune disorders
UoD Life Sciences @UoDLifeSciences
5K Followers 763 Following School of Life Sciences at the University of Dundee @dundeeuni Top University in the UK for Biological Sciences - Research Excellence Framework 2021
Mahima Swamy @MahimaSwamy
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Bill Carton @CartonBill
355 Followers 483 Following Senior Scientist at @PneumagenLtd working on respiratory tract infections. Former PhD student @sapkota_mrcppu @mrcppu.
Microbiology Society @MicrobioSoc
76K Followers 1K Following Microbiology Society: A world in which the science of #microbiology provides maximum benefit to society | https://t.co/tMDafCE6df
Alejandro Brenes @AJ_Brenes
974 Followers 1K Following not active here, find me on 🦋 https://t.co/NLi6SNFuZp
Sven Lange @Sven_M_Lange
341 Followers 485 Following Structural Biochemist. Postdoc in Brown lab @harvardmed with interest in #ubiquitin. Formerly @mrcppu @mpimoph. He/Him.
Nur Kocatürk @nurkocaturk
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Ian Kelsall @Dr_Ian_Kelsall
466 Followers 429 Following Senior Research Associate @mrcppu, working in the lab of @YKulathu. Interested in ubiquitin, RBR ligases, innate immune signalling and heavy metal 🤘
Harmit S. Malik @HarmitMalik
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Frances Arnold @francesarnold
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Elisha McCrory @elishamccrory_
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WEHI (Walter and Eliz... @WEHI_research
21K Followers 2K Following We research and develop treatments for cancer, diseases of development and ageing, immune disorders and infections.
bioRxiv @biorxivpreprint
141K Followers 23 Following Daily summaries of preprints posted in each bioRxiv Subject Area. Find ways to get social media alerts to individual papers at https://t.co/wrlEW1phDV
Alessio Ciulli @alessiociulli
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Jen Heemstra @jenheemstra
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Jonathan Pruneda @jnpruneda
1K Followers 593 Following Associate Professor at Oregon Health & Science University studying microbial interference in host ubiquitin signaling. Formerly @UWBiochemistry and @MRC_LMB.
James Murphy @pseudokinase
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Pedro Beltrao @pedrobeltrao
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526 Followers 458 Following Postdoctoral Fellow in @komander_lab at @WEHI_research | Protein Structure-Function | I love dancing & painting | I seek opportunities to learn
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Leonie Unterholzner L... @UnterholznerLab
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Eric Lander @eric_lander
55K Followers 76 Following Geneticist, mathematician and teacher. Director, Broad Institute of MIT and Harvard. OSTP Director-nominee and Presidential Science Advisor for @JoeBiden
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19K Followers 407 Following Historic airfield | Interactive Museum | Air Shows | Part of Imperial War Museums @I_W_M Our Social Media House Rules are available on the IWM website.
Hsiu-Chuan Lin @HsiuChuan_Lin
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Mark Cowley @markjcowley
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Sergey Ovchinnikov @sokrypton
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Dr. Rajesh Khanna of ... @KhannaLabUF
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241 Followers 222 Following Cytokines activate me, music soothes me, viruses thrill me
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312 Followers 187 Following Scientist, Dermatologist, Husband, Father of 3 ☀️ Project Group Leader @ Max Planck Institute of Biochemistry Spatial and single-cell proteomics in Dermatology
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OmicVision @OmicVision
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Tej @scienthusiast
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Michel Goedert @MichelGoed
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The Netherlands Cance... @NKI_nl
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Clarivate for Academi... @ClarivateAG
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ORCID Organization @ORCID_Org
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3K Followers 2K Following The Luxembourg Institute of Health has decided to suspend its account on X (formerly Twitter).You can continue to follow us on LinkedIn, Facebook, and Instagram
Anna Obenauf @obenaufa
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51 Followers 56 Following I'm a wormie, completely in love of C. elegans. Now I'm investigating meiosis.
BioTechniques @MyBioTechniques
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RARE Revolution Magaz... @RareRevolutionM
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790 Followers 526 Following professor at KU Leuven, Faculty of Bioscience Engineering and Leiden University, Institute for Biology, scientist, computational biology, data mining
chrisqs @chrisqs5
30 Followers 93 Following This account will henceforth move to Bluesky https://t.co/0osRIAfuvV Please come and find me there!
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protocols.io @protocolsIO
6K Followers 13 Following A secure platform for developing and sharing reproducible methods.
Jason C. Marvin, PhD ... @JasonCMarvin
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Jason Sheltzer @JSheltzer
19K Followers 2K Following Assistant prof at @StanfordMed. Interested in aneuploidy, mitotic kinases, cancer therapeutics, and drug development. Co-founder x2.
Shalin Naik @shalinhnaik
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