Sc2.0 @SynGenome
International team building the world's first designer eukaryotic genome...thinking about what's next...Synbio enthusiasts. Tweets by Sc2.0 consortium members syntheticyeast.org Joined February 2015-
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Sc2.0 retweeted
Thank you for highlighting this @TwistBioscience - hope you are keen on many more synthetic chromosome/genome projects!
The work developing a synthetic yeast genome, Sc2.0, is a landmark for #synbio. We are thrilled that @TwistBioscience DNA was used to support the effort: “Design, construction, and functional characterization of a tRNA neochromosome in yeast” bit.ly/3R5q2m9
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Sc2.0 retweeted
A yeast strain with over 31% synthetic genome displays normal morphology and budding behavior >>> bit.ly/47pzsPr @CellPressNews @JefBoeke @caiyizhi @SynGenome
Sc2.0 retweeted
Scientists @BABlount @UoNLifeSci & @ProfTomEllis @Imperialcollege are poised to create the most advanced “synthetic” organism ever made — a baker’s yeast that is controlled entirely by human-made genetic instructions. Read more @thetimes ▶️ ow.ly/hTEb50Q6nZ9
Sc2.0 retweeted
Congrats to the Sc2.0 community on this huge achievement. Just wait for our Oxytricha trifallax 2.0!!
Happy Sc2.0 day. 10 new papers published today in Cell Genomics, Cell and Molecular Cell. Telling the story of 8 more completed chromosomes (including ours) and a tRNA neochromosome and bringing more than half the syn genome together into a single cell. cell.com/cell-genomics/…
Sc2.0 retweeted
Now online! Design, construction, and functional characterization of a tRNA neochromosome in yeast dlvr.it/Syc6fM
Sc2.0 retweeted
We finally finished our synthetic chromosome! @ProfTomEllis @glen_gowers I'm just going to collapse in this corner now... cell.com/cell-genomics/…
Sc2.0 retweeted
A strain of yeast has had half its DNA replaced with artificial chromosomes in a major step towards creating the first complex cell with an entirely synthetic genome newscientist.com/article/240176…
Sc2.0 retweeted
Now online! Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions dlvr.it/SyZRQf
Sc2.0 retweeted
Researchers have achieved a significant milestone by successfully integrating more than seven synthetic chromosomes into a single yeast cell, yielding a strain with over 50% synthetic DNA that can survive and replicate similarly to wild yeast strains: synbiobeta.com/read/its-alive…
Sc2.0 retweeted
It’s a great pleasure to see the tRNA neochromosome finally reaching the light of day at @CellCellPress! I’m sharing co-first authorship with @DSchindler_PDR, with @caiyizhi at the helm and under the guidance of @JefBoeke. Find the article here: sciencedirect.com/science/articl…
Sc2.0 retweeted
Congratulations to all the consortium members for their hard work and contributions towards a landmark achievement in synthetic biology! @PaulsenLab @SynGenome
Sc2.0 retweeted
How do you build a synthetic yeast genome with thousands of designed changes and a new-to-nature genome diversification ‘scramble-ing’ mechanism?
Sc2.0 retweeted
Biologists have produced a strain of yeast whose genome is more than 50% synthetic DNA go.nature.com/3Qtp2a3
Sc2.0 retweeted
“Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast” @CellGenomics cell.com/cell-genomics/… @caiyizhi
Sc2.0 retweeted
“Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast” @cellcellpress cell.com/cell/fulltext/… @caiyizhi
Sc2.0 retweeted
#Yeast cell created with an over 50% synthetic #genome can survive and replicate similar to wild type. See below a collection of papers presenting this half-synthetic yeast and showcasing the #SyntheticYeastGenomeProject (Sc2.0) @yeastgenome 🧵
Sc2.0 retweeted
Very proud of our November issue presenting the amazing work by the Sc2.0 consortium. Took me back to my #igem (2006) roots and I know this collection will be a landmark in synthetic biology. cell.com/cell-genomics/…
Sc2.0 retweeted
Check it out now in #Cell #Genomics Open Access - Rise of synthetic #yeast: Charting courses to new applications community.alliancegenome.org/t/cellpress-op…
Sc2.0 retweeted
“Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains” @CellGenomics cell.com/cell-genomics/… @JohnsHopkinsSPH Srinivasan Chandrasegaran @JefBoeke @WEIMINZHANG6
Sc2.0 retweeted
An international team of scientists led by @caiyizhi are one step closer to re-writing world’s first synthetic yeast genome. The Sc2.0 team have now recreated every chromosome in baker's yeast from scratch and combined 6.5 of them in a functional cell. 👉manchester.ac.uk/discover/news/…
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