SAGA_COMPLEX @SAGA_Complex
Multiprotein complex. About 1.6 MDa and 28x20 nm. Conserved in eukaryotes. Multifunctional. Transcriptional regulator. Eukaryotes Joined October 2018-
Tweets93
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Followers166
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Following7
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Look at me, I made it to the cover! 😊🥰
@MED_COMPLEX That's how I feel too sometimes. I think it's just our midlife crisis.
In this Review, Soffers and Workman discuss the initial discovery of the canonical SAGA complex, the subsequent studies that have shaped our view, and the latest structural work that provides insights into its function. @jerryleeworkman @ScienceStowers genesdev.cshlp.org/content/34/19-…
Check out this most recent review on my structure and function, from Jelly Soffers and @jerryleeworkman and published in @GenesDev 23 years since my discovery and we keep learning! genesdev.cshlp.org.insb.bib.cnrs.fr/cgi/content/lo…
The Novel ReNu Region of TAF12 Regulates Gcn5 Nucleosomal Acetylation pubmed.ncbi.nlm.nih.gov/32832935/
Architecture of the multi-functional SAGA complex and the molecular mechanism of holding TBP pubmed.ncbi.nlm.nih.gov/32946670/
Review by Sharon Dent and colleagues @EKoutelou on the complex functions of Gcn5 and Pcaf in development and disease sciencedirect.com/science/articl…
Review by Vikki Weake and colleagues on the Gcn5 complexes in Drosophila as a model for metazoa sciencedirect.com/science/articl…
Review by @susaopina an colleagues on the promiscuity of my subunits: Multifunctional or moonlighting? sciencedirect.com/science/articl…
My "fathers", James Brownell and David Allis at @RockefellerUniv , review the discovery of my HAT: Heading toward an elusive goal with a key biological assist sciencedirect.com/science/articl…
Review by @DowneyUOttawa on non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases sciencedirect.com/science/articl…
SAGA and TFIID: Friends of TBP drifting apart. sciencedirect.com/science/articl…
The SAGA continues: The rise of cis- and trans-histone crosstalk pathways sciencedirect.com/science/articl…
SAGA and TFIID: Friends of TBP drifting apart pubmed.ncbi.nlm.nih.gov/32673655/
The SAGA continues: The rise of cis- and trans-histone crosstalk pathways. ncbi.nlm.nih.gov/pubmed/3264535… #pubmedsearches #feedly
The yeast exoribonuclease Xrn1 and associated factors modulate RNA polymerase II processivity in 5’ and 3’ gene regions jbc.org/cgi/content/lo…
Dynamic modules of the coactivator SAGA in eukaryotic transcription. ncbi.nlm.nih.gov/pubmed/3261682…
SAGA Structures Provide Mechanistic Models for Gene Activation pubmed.ncbi.nlm.nih.gov/32531226/
This CRISPR screen identifies my DUB activity as an important regulator of regulatory T cells, via stabilization of the Fox3p transcription factor. disq.us/t/3o9x9ts
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Carla Concepcion Cris... @cp_concepcion
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Heqiao Zhang @HeqiaoZ
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Kadoch Lab @kadochlab
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David Lara-Astiaso @Davidlarastiaso
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Gene Regulation @generegulation
14K Followers 6K Following Gene regulation community. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics. Personal views do not represent @TeifLab. Mostly moved to 🦋 and 🐘
Nucleosome papers �... @Nucleosome_Bot
5K Followers 8 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]
Transcription Factors @AllAboutTFs
2K Followers 3 Following I will tweet about TFs: past, present and some future. Tweets are not endorsements. Follow for more TF related science.
SWI/SNF @swisnf
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Chromatin Haiku @ChromatinHaiku
6K Followers 1K Following Chromatin haiku / To describe and bring alive / DNA, histones
TF binding papers �... @TF_binding_bot
4K Followers 10 Following Papers on transcription factor binding #TFbinding. Maintained by @TeifLab. Also see @nucleosome_bot, @CTCF_papers, @DNAbinding, @cfDNA_papers, @generegulation
MED_COMPLEX @MED_COMPLEX
985 Followers 231 Following I'm the Mediator Complex but you can call me MED. I'm essential for gene transcription & my best friend is the RNA pol II. And I have a head, a body & a tail.You might like
