PRED4 @PRED4research
Predicting serious drug side effects on Gastroenterology Please note that this site is only monitored during working hours ibdresearch.co.uk Exeter Joined January 2014-
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Week 2 @NIHRresearch. ✅84 🏥 in set up. ✅30 🏥 ready to 🟢! ✅52 patients recruited. ✅ 3500 patient packs sent. Active #IBDresearch collaborations in 🏴 🏴 🏴
Following the guidance issued by the NIHR (link below), we are pausing the PRED4 study until further notice. Thank you for your understanding at this extremely difficult time, the Exeter team are available via email to answer any queries you may have. nihr.ac.uk/news/dhsc-issu…
As of today the Exeter IBD Research admin team will be working from home. @PANTSresearch @PRED4research
This is @PANTSresearch - collaborative UK IBD research at its best. Led tirelessly by @tariqahmadIBD + @ClaireBewshea ... driven by @DrNickKennedy + @alehins ... & many of us with brilliant sites & >1500 patients, prospective data and a gene hit of direct clinical utility.
This is @PANTSresearch - collaborative UK IBD research at its best. Led tirelessly by @tariqahmadIBD + @ClaireBewshea ... driven by @DrNickKennedy + @alehins ... & many of us with brilliant sites & >1500 patients, prospective data and a gene hit of direct clinical utility.
Genetic variant influences anti-TNF immunogenicity in Crohn’s healio.com/gastroenterolo… HLA-DQA1*05 essentially doubles the rate of immunogenicity @HealioGastro @AGA_Gastro
The main treatment for #Crohns disease is a TNF-antibody, but many patients develop an immune response. It turns out that a common HLA allele (40% w/ European ancestry) is tied to this problem gastrojournal.org/article/S0016-… @AGA_Gastro @AmerGastroAssn #PGX
Our #GWAS of immunogenicity to anti-TNF in #Crohns has just gone online at @AGA_Gastro. Thanks to all the patients, PIs, nurses and the hard work of the @PANTSresearch team led by @tariqahmadIBD and @anderson_carl's group at @sangerinstitute! gastrojournal.org/article/S0016-…
Something we participated here at Royal Berks! Met some amazing patient over the years and it has been great to work with @PRED4research
Something we participated here at Royal Berks! Met some amazing patient over the years and it has been great to work with @PRED4research
It has been a privilege to contribute to this enormous project, as well as adjudicate some arms, and be a part of the publications arising from PRED4. Tariq Ahmad changed the world of Pharmacogenetics in IBD.@CDDFTRnI
It has been a privilege to contribute to this enormous project, as well as adjudicate some arms, and be a part of the publications arising from PRED4. Tariq Ahmad changed the world of Pharmacogenetics in IBD.@CDDFTRnI
BRAVO @PRED4research Tariq & @ClaireBewshea - Not only transforming the pharmacogenetic landscape in #IBD, but also launching a vintage era for IBD research in the UK - collaborative, #bigdata projects - demonstrating what is possible with vision & grit on a shoestring.
BRAVO @PRED4research Tariq & @ClaireBewshea - Not only transforming the pharmacogenetic landscape in #IBD, but also launching a vintage era for IBD research in the UK - collaborative, #bigdata projects - demonstrating what is possible with vision & grit on a shoestring.
... from 1st September 2019 as we now have enough recruits to the study we will be closing all arms except anti TNF induced skin reactions in IBD (ANTS) so please keep recruiting to ANTS! Thank you for your support 🧬😀
3000 patients 👩👩👦, 7 years 🗓️, 9 arms 🧬, 162 sites 🏥 later... thank you to all the patients, research nurses and PIs who have contributed to @PRED4research....
Genetic Variants Associated With Thiopurine-Induced Myelosuppression in IBD ja.ma/2EppilB
@PRED4research @PANTSresearch @RDEResearch @OfficialNIHR @UKPGxStratmed
This is PANTS! A UK Longitudinal multi- centred observational study - possibly the largest of it kind investigating anti-TNF drug response /or not in Crohn’s patients.(Dr T Ahmad) @UofE_Research @RDEResearch @PANTSresearch #research #personalised
This is PANTS! A UK Longitudinal multi- centred observational study - possibly the largest of it kind investigating anti-TNF drug response /or not in Crohn’s patients.(Dr T Ahmad) @UofE_Research @RDEResearch @PANTSresearch #research #personalised
@OfficialNIHR @NIHRCRN_SWPen @NIHRCRN
First paper from PANTS, our UK-wide 1610-patient study of #antiTNF in #Crohns has been published online. Thanks to the patients, doctors, nurses & #research teams who made this possible! @gutsandgenes @RDEResearch @UniofExeter thelancet.com/journals/langa…
@PRED4research @gutsandgenes @CrohnsColitisUK
@PRED4research @gutsandgenes @CrohnsColitisUK
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84 Followers 48 Following Hello 👋, latest news from the Exeter IBD Research Group 🧬💊. #rightdrugrightdosefirsttime #researchmatters @pred4research @pantsresearch @clarityibdAmethyst Events @AmethystCME
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267 Followers 358 Following Lecturer in health data science and director of Exeter's MSc. Martial Artist, Mathematician, Biomedical Statistician. Views my own. Mostly just retweets dogs.Carl Anderson @anderson_carl
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12K Followers 595 Following Official account for the Royal Devon University Healthcare NHS Foundation Trust. Monitored Mon-Fri, 9-5. Please note: this is not an emergency service.NIHR Research @NIHRresearch
99K Followers 4K Following Sharing news and information from the National Institute for Health and Care Research (NIHR). We fund, enable and deliver world-class health and care research.PANTS @PANTSresearch
175 Followers 54 Following Personalising Anti-TNF Therapy in Crohn's disease. Please note that this account is only monitored during working hours.Can't believe it's over 11 years since the 1st patient was recruited into PANTS. What a #collaborative journey. Supported /funded by @RDEResearch @NIHRresearch @ExeterNihr @CrohnsColitisUK @CrohnsColitisC3 @GutsCharityUK @Merck @abbvieuk @Pfizer_UK @immunodiagnostik
PANTS - Maximising patient data and samples + fantastic collaboration Recruitment March 2013- July 2016 PANTS - FACTS 👥 1600+ patients 🩺13900 patient visits 🏥118 NHS Hospitals 👩💻300 NHS research staff 🧪~90000 frozen samples 💩~6000 poo samples @tariqahmadIBD
PANTS - Maximising patient data and samples + fantastic collaboration Recruitment March 2013- July 2016 PANTS - FACTS 👥 1600+ patients 🩺13900 patient visits 🏥118 NHS Hospitals 👩💻300 NHS research staff 🧪~90000 frozen samples 💩~6000 poo samples @tariqahmadIBD
Week 2 @NIHRresearch. ✅84 🏥 in set up. ✅30 🏥 ready to 🟢! ✅52 patients recruited. ✅ 3500 patient packs sent. Active #IBDresearch collaborations in 🏴 🏴 🏴
Something we participated here at Royal Berks! Met some amazing patient over the years and it has been great to work with @PRED4research
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn’s disease: the prospective, multicentre PANTS cohort study - thelancet.com/journals/langa… #crohnsdisease #crohns #IBD
It has been a privilege to contribute to this enormous project, as well as adjudicate some arms, and be a part of the publications arising from PRED4. Tariq Ahmad changed the world of Pharmacogenetics in IBD.@CDDFTRnI
3000 patients 👩👩👦, 7 years 🗓️, 9 arms 🧬, 162 sites 🏥 later... thank you to all the patients, research nurses and PIs who have contributed to @PRED4research....
BRAVO @PRED4research Tariq & @ClaireBewshea - Not only transforming the pharmacogenetic landscape in #IBD, but also launching a vintage era for IBD research in the UK - collaborative, #bigdata projects - demonstrating what is possible with vision & grit on a shoestring.
3000 patients 👩👩👦, 7 years 🗓️, 9 arms 🧬, 162 sites 🏥 later... thank you to all the patients, research nurses and PIs who have contributed to @PRED4research....
Congratulations to Dr Timothy McDonald, Consultant Biochemist leading the Academic Department of Blood Sciences at the RD&E and a world-leading #diabetes specialist at the @ExeterMed, who has been nominated to receive the prestigious NHS Healthcare Scientist of the Year award!
Genetic Variants Associated With Thiopurine-Induced Myelosuppression in IBD ja.ma/2EppilB
@PRED4research @PANTSresearch @RDEResearch @OfficialNIHR @UKPGxStratmed
Genetic Variants Associated With Thiopurine-Induced Myelosuppression in IBD ja.ma/2EppilB
This is PANTS! A UK Longitudinal multi- centred observational study - possibly the largest of it kind investigating anti-TNF drug response /or not in Crohn’s patients.(Dr T Ahmad) @UofE_Research @RDEResearch @PANTSresearch #research #personalised
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn’s disease: the prospective, multicentre PANTS cohort study - thelancet.com/journals/langa… #crohnsdisease #crohns #IBD
@OfficialNIHR @NIHRCRN_SWPen @NIHRCRN
Moving closer to personalised medicine in IBD.. the benefits of international collaboration #research #ibdcollaboration #exeteribdresearch
@OfficialNIHR @NIHRCRN
This is PANTS! A UK Longitudinal multi- centred observational study - possibly the largest of it kind investigating anti-TNF drug response /or not in Crohn’s patients.(Dr T Ahmad) @UofE_Research @RDEResearch @PANTSresearch #research #personalised
@PRED4research @RDEResearch @CrohnsColitisUK
It was routine monitoring that raised the red flag that Vicky Melluish’s #CrohnsDisease treatment needed urgent adjustment. Blood tests showed her white blood cell count had plummeted dangerously low meaning she was at risk of infection. medicine.exeter.ac.uk/news/articles/…
@PRED4research @gutsandgenes @CrohnsColitisUK
Safer care for people with Inflammatory Bowel Disease thanks to research @UniofExeter & @RDEhospitals Find out more by watching great piece by @JennyWalrond on @BBCSpotlight iPlayer from 8 mins, 33 secs: bbc.in/2Vm6ytR
Congratulations to Tariq Ahmad (@gutsandgenes), @JamesGoodhand1 and @ClaireBewshea for leading this important project! @PANTSresearch
First paper from PANTS, our UK-wide 1610-patient study of #antiTNF in #Crohns has been published online. Thanks to the patients, doctors, nurses & #research teams who made this possible! @gutsandgenes @RDEResearch @UniofExeter thelancet.com/journals/langa…
New #genetic #discovery will make treatment for #Crohndisease far safer, by identifying patients who are at risk of potentially deadly drug side effects. Read about Vicky Melluish’s case here: medicine.exeter.ac.uk/news/articles/…
@PRED4research @PANTSresearch MOOC introducing clinical research. Learning at your own pace.
Great introduction for anyone interested in / new to research @nurseannasteele @JoStudham @RDEResearch good to share with our teams
WATCH: @BBCTwo 'How the NHS changed our world' on catch up now, or Live tonight at 7pm, where #NIHRTrainees feature in the programme. #NHS70 #IAmResearch #BRC #NIHR bbc.co.uk/programmes/b0b…