Long-term ketamine usage messes up your brain. People are using K as a party drug because you do it like coke and it lasts for about as long. They tell themselves it's an antidepressant. But in the long term it has major negative impacts. ncbi.nlm.nih.gov/pmc/articles/P…
If you're skeptical of the result, I recommend checking out the full paper. It's a review of a bunch of studies, including trials in animals... ncbi.nlm.nih.gov/pmc/articles/P…
@Noahpinion 2.4g a day seems like a very large amount to be taking daily?!
@Noahpinion Is this for casual use? By way of comparison, alcohol abuse can mess you up, but that doesn't apply to all 'long-term' but low level alcohol consumption?
@Noahpinion You fundamentally do not understand the topic you're discussing. Ketamine use is in no way similar to cocaine.
This is about addicts: "2–9.7 years; mean use 2.4 g/day" From this very study: "Low dose, twice weekly ketamine schedules have strong antidepressant effects in depressed patients" "Furthermore, low dose ketamine schedules in mice increased sprouting in the medial prefrontal cortex compared to saline injections" "The reviewed brain differences might have been pre-existing and may have predisposed subjects to ketamine dependence. This is plausible considering that many of the observed brain differences concerned prefrontal regions that are crucial for inhibiting addictive behaviors."