Niccolò Arecco @NccAcc
Twitter is dead, find me at https://t.co/gIJVhVbCKn Now: Postdoc @CRGenomica. Previously: @EMBO Postdoc Fellow, PhD @EMBL. Semi-Professional Pizza Enthusiast. ni-ar.github.io Barcelona, Spain Joined February 2014-
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.@GoogleDeepMind are you planning to release #AlphaGenome predictions for each 1Mb bin of the human genome at some point? It would be great to have them in @ensembl or @ucsc genome brower. (Similarly to AlphaFold predictions for all proteins on UniProt) Thanks!
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Niccolò Arecco retweeted
Earlier this year, I learned I have a pathogenic variant in BRCA2, which gives me a very high lifetime risk of breast cancer (55-69%), as well as an increased risk of ovarian cancer (12-29%) and pancreatic cancer (5-10%). 🧵1/ …
Niccolò Arecco retweeted
Excited to share that the AlphaFold 3 model code and weights are now available for academic use. Looking forward to seeing what new research this unlocks and how the research community builds on AlphaFold 3 for scientific discoveries github.com/google-deepmin… 1/2
Niccolò Arecco retweeted
Xciting news + Jobs alert! 🚨 After wonderful years at @CRGenomica, we are relocating beginning 2025 to @ChuSteJustine at @UMontreal. If you want to be part of @PayerLab 2.0, come and join us! We are hiring at all levels – see job ads in the thread 🧵below. 👇 1/5
@TriggerLoop and only ~4000 words to make sense of it
@jordixiol I'm not an expert here, can you clarify how come a drug that failed phase 3 can still get FDA approval?
@marcotrizzino You can get them from an ENSEMBL GTF file: wget ftp.ensembl.org/pub/current_gt… zcat Homo_sapiens.GRCh38.112.gtf.gz | head -n 150 | grep -v "^#" | grep "exon" | cut -f 1,4-7 | uniq Of course there'll a lot of crap in it
This is exciting!
We love the excitement & results from the community on AlphaFold 3 and are doubling the AF Server daily job limit to 20. Happy to also share that we're working on releasing the AF3 model (incl weights) for academic use, which doesn’t depend on our research infra, within 6 months.
THIS! 👇
We love the excitement & results from the community on AlphaFold 3 and are doubling the AF Server daily job limit to 20. Happy to also share that we're working on releasing the AF3 model (incl weights) for academic use, which doesn’t depend on our research infra, within 6 months.
Where's the code+params? Please!
Announcing AlphaFold 3: our state-of-the-art AI model for predicting the structure and interactions of all life’s molecules. 🧬 Here’s how we built it with @IsomorphicLabs and what it means for biology. 🧵 dpmd.ai/3URDiNo
@R_Mallarino @JorgeMorenoPhD @Nature Super cool story and thanks for all those marsupial genomes! 🙏
@cemkansu Is there a way to de-activate animations?
"2/3 of of alternative TF isoforms exhibit differences in one or more molecular activities" biorxiv.org/content/10.110…
Niccolò Arecco retweeted
Very happy to see our work on the unexpected role of splicing in regulating Polycomb assembly, occupancy, dimerization and histone mark deposition. Great team work with @mirimiam, @NccAcc, @Ivuaenneo, among others! sciencedirect.com/science/articl…
For the busy people with no time, Ivano made this great meme to capture the essence of our findings 😎
PRC2 with splicing characteristics Our story is finally out on @MolecularCell TL;DR:
@PayerLab @mirimiam @Gabrijela_D @MolecularCell @Ivuaenneo @DiCroceLab Maybe the X chromosome next? 😍
Niccolò Arecco retweeted
Online Now: Alternative splicing decouples local from global PRC2 activity dlvr.it/T3jTqH
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damiano cianferoni @damianocianfe
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22K Followers 2K Following We are an international biomedical research lab based in Barcelona, a unique and interdisciplinary centre at the forefront of life sciences. We are @icerca
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Grisha Zolotarov 🇺... @zolotarg
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Miquel Anglada-Girott...
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