Morgan Cheatham, MD @morgancheatham
partner, head of healthcare + life sciences @BreyerCap | medical geneticist @harvard | editorial @NEJM_AI @decodingbio | bayesian morgancheatham.substack.com Brooklyn Joined October 2016-
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@nikillinit there are some great pilots of this underway: news.med.miami.edu/sunshine-genet…
Decoding Bio has joined Arkaea Media Group! what started as a weekly blog among friends became something none of us could have predicted: a community at the forefront of the most consequential moment in biology. i'm so grateful to my co-founders, @ameekapadia, @pablolubroth, @KetanYerneni, and @patricksmalone. thank you to our readers, and to the founders, scientists, and investors who shared their work with us along the way. good writing has become a public good, and the embrace of Decoding Bio convinced us it was worth scaling. the best of Decoding Bio is ahead! 🧬
BIG NEWS: I'm thrilled to announce that Arkaea Media Group has acquired Decoding Bio, one of the leading media brands in biotechnology. This is our first acquisition and a continuation of our thesis to build media for the most consequential industries in the world. Decoding Bio
Until now, physicians using AI in clinic had to assemble the patient’s context themselves. Allergies, comorbidities, medications, prior procedures, copy-pasted in from the chart. Today we’re announcing a partnership with @CedarsSinai. OpenEvidence now works directly inside Epic, drawing on the patient’s full record and interpreting the medical literature through the lens of that specific patient. Cedars-Sinai is the first academic health system to deploy patient-aware clinical intelligence at enterprise scale. The clinician asks a complex question in natural language. The answer reflects both the best available evidence and the patient in front of them. Patient data is never stored after the clinical session or used for any other purpose.
excited to co-chair the @bioitworld executive summit this week in Boston today! this is our largest program to-date, with leaders from @generate_biomed, @FlagshipPioneer, @ThirdRockV, @nablabio, @sanofi, @Amgen, @google, and @EliLillyandCo all under one roof.
@bznotes @sahir_raoof @sahir_raoof is exceptional, can't wait to see where he takes proximal VC from here!
@ShivdevRao @HarryStebbings @twentyminutevc instant classic 🙏🏽
So much fun to sit down with @HarryStebbings on @twentyminutevc this week. The time flew by, I learned a lot just from being on the other side of the conversation. We talked about agent-native companies and Conway’s Law, why healthcare GTMs are often counterintuitive, and why Costco is a source of inspiration. Grateful to you, Harry 🙏.
I have interviewed 1,000s of the world's best founders over the past decade. Few have impressed me like @ShivdevRao at @AbridgeHQ. He navigated a brutal 5-year wilderness before exploding into one of the most dominant forces in vertical AI. Today, Abridge is a $5.3BN
“We did the hardest thing in the history of American health care. We got the majority of American doctors to all voluntarily adopt a single technology platform.” NBC News on how that happened, what U.S. physicians actually do with OpenEvidence, and how partnerships with NEJM, JAMA, NCCN, and Wiley make it possible.
So excited @morgancheatham @bretbostwick
.@BreyerCap is leading the $13M seed financing of ParcelBio, a company developing a new class of durable mRNA medicines. mRNA has transformed vaccines but has not yet produced a class of chronic, disease-modifying medicines. the reason is durability. ParcelBio's APEX platform
@morgancheatham Fantastic
the biotech industry has spent five years negotiating a "trilemma" in RNA across peak expression, durability, and manufacturability: pick two. this week, we announce @BreyerCap's newest investment in ParcelBio. APEX is the first platform we have seen that delivers all three.
@chrissyfarr wrote a couple posts on this back in 2024 that have aged decently - usage-based: morgancheatham.substack.com/p/who-pays-for… - performance-based: morgancheatham.substack.com/p/who-pays-for…
the biotech industry has spent five years negotiating a "trilemma" in RNA across peak expression, durability, and manufacturability: pick two. this week, we announce @BreyerCap's newest investment in ParcelBio. APEX is the first platform we have seen that delivers all three. @bretbostwick, @jimihendrixlive, and i detail our thesis here:
@xinjin @BreyerCap @DWeinberg305 🙏🏽🙏🏽🙏🏽
.@BreyerCap is leading the $13M seed financing of ParcelBio, a company developing a new class of durable mRNA medicines. mRNA has transformed vaccines but has not yet produced a class of chronic, disease-modifying medicines. the reason is durability. ParcelBio's APEX platform is the first we have evaluated that delivers high peak expression, sustained duration, and tunability inside a linear, manufacturable architecture. we are grateful to back @DWeinberg305 and Chris Carlson, two exceptional scientists developing the platform they are uniquely positioned to build. APEX preclinical data debuts at #ASGCT on May 14. thank you to @RLCscienceboss of @endpts for sharing the story! we will share our full thesis post tomorrow. @jimihendrixlive @bretbostwick
welcome to the @BreyerCap portfolio! @jimihendrixlive @bretbostwick
Exclusive: ParcelBio is launching with $13M to develop longer-lasting mRNA therapies, starting with an in vivo CAR-T program. endpoints.news/former-orbital…
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