Gabriel Loeb @LoebLab

Seeking molecular mediators of kidney disease through human genetics, genomics, and novel experimental models. @UCSF, @UCSFNephrology Joined August 2022

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Gabriel Loeb @LoebLab

3 weeks ago

Thank you to @kidneyomicsamps and @MagdalenaRiedlK for the thoughtful editorial on our paper functionalizing 𝘗𝘒𝘋1 variants and implications for polycystic kidney disease (ADPKD) genetic testing and treatment. DOI: 10.1681/ASN.0000001174 journals.lww.com/jasn/fulltext/…

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Gabriel Loeb @LoebLab

6 months ago

We are constantly thinking about how to integrate human genetics and better experimental models to identify the mechanisms of human disease @UCSFNephrology, @IHG_at_UCSF, @UCSFDOM . Funding for the next generation of medicine from @NIH. Critiques and feedback welcome!

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Gabriel Loeb @LoebLab

6 months ago

@BrandesNadav, Fnu Ritu, @yimmieg @ReiterLab @willowcoyote. journals.lww.com/jasn/abstract/…

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Gabriel Loeb @LoebLab

6 months ago

Polycystic kidney disease is the most common monogenic cause of kidney failure and affects over 10 million individuals. We've known most PKD is caused by mutations in PKD1 for over 30 years. But how PKD1 prevents disease has remained mysterious, limiting effective therapy.

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Matt Lanktree | #NephroGenetics @MattLanktree

9 months ago

What an awesome session on common variant CKD genetics @ASNKidney #KidneyWk @kidneyomicsamps @LoebLab @LimdiNita

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Sol Carriazo, Neph. @Nefrontera

9 months ago

Nice talk by @LoebLab at #KidneyWk! -Approved targeted therapies for monogenic kidney disease -Next generation therapies for genetic disease

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Anuja Java, MD (she/her) @anuja_java

9 months ago

Incredible session on Genetics in Kidney Disease #KidneyWeek @ASNKidney Outstanding organization & insightful talks by @Vishal_D_Patel #DanielGale #AliGharavi #GabrielLoeb Grateful for the opportunity to present on Genetics of TMA🙏 Thx #ArleneChapman & #EmilieCornecLeGall

Sol Carriazo, Neph. @Nefrontera

9 months ago

🧬Very nice talk about genetics of TMA by @anuja_java at #KidneyWk 👉🏽 Interplay between genetics and triggers 👉🏽Who should we test?

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Gabriel Loeb @LoebLab

a year ago

Thank you @ASNKidney! Our lab is very grateful to receive the 2025 Carl W. Gottschalk Research Scholar Grant. Read more about the work here: kidneycure.org/pages/qa.aspx?….

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Gabriel Loeb @LoebLab

a year ago

@ksusztak @UCSFNephrology Grateful for the chance to learn from @ksusztak, @parkercwilson, and others @Penn and @PennKidney. So much science to be excited about.

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Katalin Susztak @KSusztak

a year ago

#Whyscience Day51🧠✨A strong finish to our Renal Grand rounds series by a rising star physician scientists ⁦@LoebLab⁩ ⁦@UCSFNephrology⁩ Pushing the frontiers of kidney genomics and single cell omics. The future of nephrology is bright🔆

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Gabriel Loeb @LoebLab

a year ago

Are you content with your current chance of developing Alzheimer’s disease?

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Gabriel Loeb @LoebLab

a year ago

Steven Pinker: And if you’re still skeptical that universities are worth supporting, consider these questions: Do you think that the number of children who die every year from cancer is just about right?

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Gabriel Loeb @LoebLab

2 years ago

Exciting paper by @CanaudLab in @jclinicalinvest--doi.org/10.1172/JCI176…. 1) Somatic mutation as a (presumably) very rare cause of FSGS, 2) Targeting the mutated gene PIK3CA is helpful in multiple mouse FSGS models, 3) Activity of podocyte targeted therapy in mouse FSGS.