Kerry Dooley Young 🇺🇦 🇺🇦 🇺🇦 @KDooleyYoung
I write about the promise and practice of medicine, often looking at how well treatments work and what they cost. Happily freelancing. kerrydooleyyoung.com Joined September 2009-
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People often think the most important part of science is the statistical analysis. But they’re wrong. The most important part is understanding the data. Who collected it, when, where, why, how, and from whom? Who entered and cleaned it, when, where, why, how, and for whom?
Psoriasis Medication Analysis Shows a Path for Comsidering US Drug Costs. Thanks @KDooleyYoung @Medscape for covering our recent @PORTAL_Research paper in @JAMADerm. medscape.com/viewarticle/ps…
Our editorial accompanying @bnrome article also highlighted in the @Medscape article by @KDooleyYoung, available here: jamanetwork.com/journals/jamad…
Are AI-powered skin-check tools on the horizon for dermatologists, PCPs? medscape.com/viewarticle/99… by @KDooleyYoung via @Medscape Great summary where you will understand why #dermatology is decades behind #radiology #pathology or #ophthalmology - so what next! #dermtwitter
Agree with @DutchRojas. Better to call doctors and nurses....doctors and nurses, and drop the awful "providers" jargon. In referring to a mix of doctors and nurses and NPs and PAs, "clinicians" seems less awful. At least it conveys a sense that patients are in the mix.
Agree with @DutchRojas. Better to call doctors and nurses....doctors and nurses, and drop the awful "providers" jargon. In referring to a mix of doctors and nurses and NPs and PAs, "clinicians" seems less awful. At least it conveys a sense that patients are in the mix. https://t.co/fvZUfYPZIb
Happy August recess! What a perfect time to adopt a dog!! I’ve been fostering Roscoe, the most perfect, happy pup. He’s been in the foster system for several months and is ready to thrive with his forever family. DM if interested! @HomewardTrails
Yup. These are some of the very interesting policies in a draft Medicare physician fee schedule. But this rule will mostly get attention for its lack of a "broad inflation adjuster," or base rate adjustment pegged to MEI.
Yup. These are some of the very interesting policies in a draft Medicare physician fee schedule. But this rule will mostly get attention for its lack of a "broad inflation adjuster," or base rate adjustment pegged to MEI.
This, this, this, this, this, this.... or "isso!" for the Portuguese speakers out there..
This, this, this, this, this, this.... or "isso!" for the Portuguese speakers out there..
Nothing quite says "summer on the health beat in DC " to me like digging into the draft Medicare physician fee schedule at a concert at Ft. Reno.
Until this week, I remained a NoVid, which I chalked up to being fairly cautious, fully vaxxed & a bit lucky. This week my luck ran out. My case is a cautionary tale, particularly for the “just a cold” folks. Mine definitely was not...I literally have scars to show for it. (1/22)
What a beautiful lede ...."Making the yogurt of the future requires a cast of 21st-century helpers: machine learning, gut science and even a mysterious artificial stomach."
What a beautiful lede ...."Making the yogurt of the future requires a cast of 21st-century helpers: machine learning, gut science and even a mysterious artificial stomach."
This is going to cause a lot of incidentalomas, unnecessary procedures and stress…
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3K Followers 1K Following historian of science, medicine, and technology at Johns Hopkins Universitylol some hospitals are still posting this sludge to be compliant with federal price transparency law x.com/bobjherman/sta…
Person: Yes, hello, I heard there is a new hospital price transparency law. I'm trying to be a Good Consumer, so I was wondering if you could share the machine readable fi- Hospital: lol, here you go, enjoy. cdn.iuhealth.org/resources/35-1…
10) Finally the route to accelerated approval requires expertise and experience in a given disease and the risks and benefits of interventions and the endpoints. It requires collaboration of regulators, Pharma, investigators, patients, and patient organizations.
9) Disease matters. Extrapolating failures from various hard to treat cancers where response often doesn’t equate clinical benefit (either because the measurement is flawed or the benefit achievable with our current understanding is small) to all cancers is a fallacy.
7) Important: The purpose of accelerated approval is to help patients. That is our one and only goal. We do not want a net loss of lives because we are focused on being text book perfect. It’s a risk benefit judgment call.
6) Important: If a drug approved is priced exorbitantly it doesn’t mean the whole accelerated approval pathway is at fault. It means we have to separately reform the way drug prices in the US are set to be proportional to the added value they provide. It is a concern.
5) Important: If a confirmatory trial is not done in a timely manner that doesn’t mean the accelerated approval pathway is wrong. It means either regulators for a good reason have allowed a delay (or lack) of such a trial; or lacking such a reason it means they need to enforce
4) Important: If a confirmatory trial is negative that doesn’t mean the whole accelerated approval pathway is at fault. A small proportion of confirmatory trials will be negative — that means we have followed the principles of accelerated approval (see second tweet in thread).
3) Accelerated approval is predicated on confirmatory trials being done in a timely manner. Failure to do so should usually result in withdrawal of the accelerated approval. The FDA is currently being quite strict on this aspect.
2) The mechanism is not meant to be 100% fool proof because with such a high bar sensitivity will be low and many truly active drugs will be rejected incorrectly or greatly delayed. But it needs to be as rigorous as is reasonable so we don’t approve too many ineffective drugs.
I know patients have scanxiety but so do oncologists. Every time I open a new scan report of a patient on surveillance, I hold my breath and leap with joy when I read “no findings of locally recurrent or metastatic disease”.
An incredible honor for @statnews reporters. "STAT made a difference in the lives of patients across the nation by having the courage to pursue such a difficult story and the compassion to help those who were so callously treated by the nation’s largest health insurer.''
The Batten Medal for exceptional journalism that makes a difference to the lives of people and their communities, sponsored by editors of the former Knight Ridder, goes to @caseymross and @bobjherman of @statnews.
Some news. Professional: I'm headed back to where it all started - returning to DC after a quarter century away. I wonder if it's changed. Still Bloomberg; still health. Personal: This one is solo. Henry passed away in January. LAD MI. Brutal. He was 56. I am still wrecked
There have been a lot of changes around here — a new byline after getting married last month, and now a new job title! I am very excited to take on more responsibility to support our incredible STAT D.C. team. statnews.com/new-leadership…
Excited to share that I'm joining @statnews to run business & policy coverage. I've long admired (and envied) STAT's great reporting, and I can't wait to get started. statnews.com/new-leadership…
Folks who see my job title often assume that *I’m* going to be the one cheerleading the use of AI. I have a vision for how we should use it, but I’m the first one to hit the brakes when we shouldn’t. We need to know where we’re going before we decide if AI can help us get there.
People often think the most important part of science is the statistical analysis. But they’re wrong. The most important part is understanding the data. Who collected it, when, where, why, how, and from whom? Who entered and cleaned it, when, where, why, how, and for whom?
Thoughtful thread by @HadidiSamer regarding ODAC sponsor briefing for CAR-T in myeloma.
#mmsm Interesting to read the ODAC sponsor briefing for Ide cel and Cilta cel Few thoughts 1️⃣ OS benfiit of Cilta Cel is great to see 👇 Notice this was evident with longer follow up since at 6 months point there was slightly higher OS rate for SOC
Breaking: ODAC votes 11-0 to recommend approval of ciltacel in patients with relapsed/refractory multiple myeloma in earlier stages. I’m glad. Right call. But we need to be careful. Read on. cancernetwork.com/view/odac-cast…
I'm watching the ODAC mtg. I was recused/couldn't participate due to legal action I'm involved in against @bmsnews. Despite all the progress on myeloma treatments, the 3rd point on this slide is sobering-reminds me of the reality of my life & disease. Must make the most of today.
Our editorial accompanying @bnrome article also highlighted in the @Medscape article by @KDooleyYoung, available here: jamanetwork.com/journals/jamad…