8ème merveille @Dynero7

Biomarker tierlist: - Calcium score: 9/10 - HOMA-IR: 8.5/10 - VO2 max: 8/10 - Cystatin C: 7.5/10 - hsCRP: 7/10 - Appendicular lean mass index: 6/10 - HDL-c: 5/10 - Creatinine: 4/10 - Body mass index: 3/10 - DNA methylation age (most clocks): 2/10

Top 10 evidence-based supplements: 1. Creatine 2. Omega-3s 3. Taurine 4. Melatonin 5. Ashwagandha 6. Berberine 7. Magnesium 8. Psyllium husk 9. Glycine 10. NAC

Los hombres con mayor fuerza de agarre tienden a tener niveles significativamente más altos de riqueza, educación, empleo y estado nutricional.

keyboard_arrow_left Previous keyboard_arrow_right Next

La salud física está fuertemente ligada a las relaciones sociales porque el cerebro humano procesa las amenazas sociales (rechazo, exclusión, soledad) de manera muy similar a las amenazas físicas de supervivencia (depredadores, heridas). Cuando los humanos se sienten rechazados o solos, se activan los mismos sistemas de alarma que ante un peligro real: el sistema nervioso simpático (respuesta de lucha o huida), el eje HPA (estrés crónico) y respuestas inflamatorias del sistema inmune. Aunque estas respuestas son útiles a corto plazo para sobrevivir, cuando se activan de forma repetida por problemas sociales generan inflamación crónica, mayor riesgo de enfermedades (diabetes, problemas cardiovasculares...) y aumentan la mortalidad. El aislamiento social le duele literalmente al cuerpo porque el cerebro lo interpreta como una amenaza vital. A lo largo de la evolución, los mamíferos —y especialmente los humanos, que son una especie ultrasocial— dependieron tanto de formar parte de un grupo para sobrevivir que el cerebro terminó usando los mismos circuitos neurales (amígdala, corteza cingulada anterior, ínsula) para detectar tanto peligros físicos como sociales. Por el contrario, el apoyo social y la sensación de conexión activan circuitos de “seguridad” que inhiben estas respuestas de estrés y protegen la salud. Por eso, sentirse conectado funciona como un escudo biológico, mientras que el sentimiento de soledad actúa como un factor de riesgo tan potente como el sedentarismo, la obesidad o fumar.

keyboard_arrow_left Previous keyboard_arrow_right Next

Claude 4.8 Opus smashes GPT-5.5 and is new SOTA on GBA Eval On GBA Eval models are used as coding agents to build a working Game Boy Advance emulator from scratch within 24 hours.

numbers that actually matter for longevity ApoB resting heart rate VO2 max grip strength HRV trend

BREAKING: Largest Human Cancer Study of Ivermectin + Mebendazole Is Now PEER-REVIEWED and PUBLISHED in a MAJOR Cancer Journal 84.4% of cancer patients taking ivermectin + mebendazole for 6 months declared either CANCER DISAPPEARANCE, TUMOR REGRESSION, or CANCER STABILIZATION. Our study, “Real-world Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort,” is now peer-reviewed and published in Anticancer Research—a major international oncology journal of the International Institute of Anticancer Research (IIAR), established in 1995. The results represent one of the most compelling clinical signals ever documented for repurposed anti-parasitic therapies in oncology. A diverse population of cancer patients (n=197) was prescribed compounded ivermectin–mebendazole through a U.S. telemedicine platform, with each capsule containing 25 mg ivermectin and 250 mg mebendazole. Participants were followed for approximately six months using standardized digital surveys assessing cancer outcomes, medication adherence, and tolerability. At approximately six months post-treatment initiation, we observed an 84.4% Clinical Benefit Ratio (CBR)—meaning more than four out of five patients reported either: No evidence of disease (32.8%) Tumor regression (15.6%) or Cancer stabilization (36.1%) Importantly, adherence was remarkably high, with 86.9% completing the initial prescription and 66.4% remaining on therapy at six months. Side effects were predominantly mild and manageable, reported in 25.4% of patients (primarily gastrointestinal), with 93.6% of those experiencing side effects continuing treatment after minor dosing adjustments. This groundbreaking peer-reviewed publication was made possible through a unique collaboration between The Wellness Company, the McCullough Foundation, and the Chairman of the President’s Cancer Panel—uniting real-world clinical data, frontline medical experience, and epidemiologic expertise to evaluate inexpensive, repurposed therapies with major translational potential. With these extraordinarily promising results, double-blind, placebo-controlled clinical trials are now required. In the meantime, many cancer patients are exercising their right to try. @twc_health @McCulloughFund @IIAR_Journals @P_McCulloughMD @DrHarveyRisch @DrKellyVictory @jathorpmfm @drdrew @PeterGillooly @FosterCoulson

vitamin C as an electron donor, can regenerate damaged testosterone molecules by up to 58%. 58% is truly remarkable!

Healthy gut = Healthy mind. Unhealthy gut = Unhealthy mind. Besides depression, brain fog, Alzheimer's and anxiety, poor gut health can contribute (and might even trigger) OCD, schizophrenia and bipolar.

keyboard_arrow_left Previous keyboard_arrow_right Next

IN SUMMARY, 10 biological causes behind depression: ◇ Nutrient deficiencies (esp. magnesium + vit D) ◇ Leaky gut ◇ High cortisol ◇ Glymphatic dysfunction ◇ High inflammation ◇ Hypothyroidism ◇ Impaired glucose metabolism ◇ Impaired neurogenesis ◇ High glutamate ◇ Impaired cerebral blood flow

Depression isn't some unknown genetic condition like your doctor tells you. In fact, we know the exact biological causes behind it. Here are 10 hallmarks of depression, & what you might be able to do about each:

Dalton (Analyze & Optimize) @Outdoctrination

3 years ago

WANT TO GET MORE OUT OF LIFE? Stuck in a routine of monotony? No motivation? Like there’s no point of trying for more? There’s a biological cause (and solution) to this and it isn’t what you expect THREAD 🧵

20 99 662 385K 1K

Depression is inflammation in disguise. Inflammatory markers are higher across the board, sometimes by 2-3X, in depressed people. Anti-inflammatories: • Aspirin • Taurine • Pregnenolone/progesterone • Red light • Glycine etc should be explored.

Dalton (Analyze & Optimize) @Outdoctrination

a year ago

Depression isn't some unknown genetic condition like your doctor tells you. In fact, we know the exact biological causes behind it. Here are 10 hallmarks of depression, & what you might be able to do about each:

12 86 717 442K 1K

Low vitamin D may contribute to reduced motivation and productivity. It influences the nucleus accumbens, a brain center linked to dopamine, reward, and motivation. Dr. Eric Berg, DC, not MD; information only

People with low vitamin C levels burned 25% less fat during exercise. After vitamin C supplementation, fat oxidation increased nearly 4-fold.

What they tell you causes high blood pressure: - Salt What really does: - Cortisol - Low vitamin D - Low magnesium - Potassium deficiency - Adrenaline - Insulin resistance - Noradrenaline - High estrogen - Low progesterone - Low vitamin C - Calcium deficiency - Low GABA - High glutamate - Lack of sunlight / UV - Circadian disruption - Seed oils - Oxidative stress

Most people think inflammation is ALWAYS bad. But your body NEEDS short-term inflammation to heal. The problem is when it stays switched ON - and the best way to switch it off... Is often FOOD. Here are 10 foods that help calm chronic inflammation naturally: 👇 Worth repeating: Inflammation isn’t the enemy. ❌ Acute inflammation helps you recover from injuries, pathogens, and stress. Chronic inflammation is different. 🚨That’s when the signal never shuts off.🚨 And over time, it shows up as: - Fatigue - Brain fog - Joint pain - Migraines - Gut issues - Faster aging The goal isn’t to “eliminate inflammation.” It’s to help your body turn it on when needed… and turn it off when the job is done. ✅❌ FOOD is one of the fastest levers. Here are 10 of the best anti-inflammatory foods: 👇 1⃣ Fatty fish Salmon, sardines, herring, and mackerel are loaded with EPA and DHA. These omega-3s help lower inflammatory markers like CRP, TNF-α, and IL-6. Best for: → Joints → Brain health → Heart health Sardines on a salad = cheap, easy, elite. 2⃣ Extra virgin olive oil The magic isn’t just the fat. It’s the polyphenols. High-quality EVOO can help reduce hs-CRP, one of the simplest markers for chronic inflammation. Drizzle it raw over eggs, meat, salads, or vegetables. 3⃣ Ginger Ginger punches way above its weight. It contains gingerols and shogaols that help calm inflammation and oxidative stress. Great for: → Joint pain → Migraines → Digestion → Soreness Mix ground ginger in water, tea, smoothies, or stir fry. 4⃣ Turmeric Turmeric contains curcumin, one of the most studied anti-inflammatory compounds. But there’s a catch: Turmeric is useful, but absorption matters. Pair it with: → Fat → Black pepper → A quality source 5⃣ Berries Blueberries, blackberries, raspberries, and strawberries are rich in anthocyanins. These compounds support: → Brain health → Heart health → Blood vessels → Lower oxidative stress Pro tip: Buy frozen organic berries in bulk. They're cheaper, easier, and just as useful. 6⃣ Leafy greens Spinach, arugula, kale, Swiss chard, and bok choy bring magnesium, folate, vitamin C, vitamin K, and carotenoids. But quality matters. Most people do better with them cooked (tons of raw greens usually cause bloating). - Add them to eggs and soups - Steam them - Sauté them 7⃣ Cruciferous vegetables Broccoli, Brussels sprouts, cauliflower, and cabbage are loaded with fiber and sulfur compounds. Sulfur helps your body make glutathione… Your master antioxidant. 🛡️ Steam them, then add garlic and olive oil. 8⃣ Garlic and onions These are quiet anti-inflammatory workhorses. - Garlic brings allicin - Red onions bring quercetin Together, they support: - Blood pressure - Immune balance - Inflammatory control Add them to bowls, eggs, soups, meats, and stir fries. 9⃣Nuts and seeds Walnuts, pistachios, chia, flax, and pumpkin seeds bring fiber, minerals, and healthy fats. They’re great replacements for ultra-processed snacks. Just don’t overdo them. ❌ They’re calorie-dense and can be hard to digest for some people. 🔟 Fermented foods This might be the most important category. Your gut houses a massive part of your immune system. So if your microbiome is wrecked, your inflammatory signaling usually is too. Add: → Kefir → Yogurt → Kimchi → Sauerkraut → Raw cheese Fermented foods don’t just feed good bacteria. They bring microbes with them. ⭐️ The Bottom Line: Chronic inflammation isn’t usually a “one food” problem. It’s a pattern problem. So don’t ask: “What single food lowers inflammation?”❌ Ask: “What daily food pattern helps my immune system calm down?”✅ If you want more details on this: Check out the video below where I RANK the Top 10 Foods for fighting inflammation. 👇👇👇

7 signs your body is flooded with cortisol (& you don't realize it): 1. Random muscle twitches.

@BrandonLuuMD That's a tiny effect tho. Like 5% probably nothing

SECRETS OF PEOPLE WHO NEVER GET SICK: 1. They wash their hands far more than the average person does 2. They sleep 7 to 8 hours without compromise,immunity is built overnight 3. They manage stress actively,chronic stress is the biggest immunity killer 4. They spend time in sunlight daily for natural vitamin D production 5. They eat fermented foods regularly to keep their gut bacteria thriving 6. They rarely touch their face with unwashed hands without thinking about it 7. They hydrate constantly,dehydration weakens every immune defense you have 8. They exercise moderately too little or too much both harm immunity equally 9. They breathe through their nose,it filters pathogens that mouth breathing lets in 10. They keep their social connections strong,loneliness physically lowers immunity 11. They take zinc and vitamin C at the very first sign of anything coming 12. They spend time in nature regularly,it reduces inflammation throughout the body 13. They laugh and find humor daily,it measurably boosts immune cell activity 14. They avoid processed food most of the time,it feeds inflammation, not defense 15. They listen to their body and rest before sickness forces them to stop

Scientists claim mental illness can come from your immune system attacking your own brain, not just “psychological causes” we usually blame

keyboard_arrow_left Previous keyboard_arrow_right Next