Mary L. (Nora) Disis @DrNDisis
Director, UW Medicine Cancer Vaccine Institute. Editor in Chief, JAMA Oncology. Research: vaccines for the prevention of cancer and cancer relapse. uwcvi.org University of Washington Joined February 2015-
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We’re excited to share a new paper by CVI’s Dr. John Liao on a clinical trial for combination Pembrolizumab and low dose carboplatin in women with recurrent, platinum resistant ovarian cancer. Read more uwcvi.org/post/new-cvi-p… #ovariancancerawarenessmonth #gyncsm #immunotherapy
👨⚕️👩⚕️ Drs. Sasha Stanton (@sestant29), Nora Disis (@DrNDisis), and fellow @UWCancerVaccine researchers found that candidate targets recovered from mouse #mammary tumor models are also immunogenic in human #BreastCancer. 📚 Abstact: go.nature.com/3y780Vb
5 immune response markers might predict #COVID19 patient outcomes & possibly become useful in candidate vaccine assessment, according to @ImmunityCP @CellCellPress study @ragoninstitute & @UWMedicine headed by Galit Alter & Helen Chu bit.ly/2DrtULn
Thanks for my nicest colleagues! I am the best, because all of you! @UWCancerVaccine
Thanks for my nicest colleagues! I am the best, because all of you! @UWCancerVaccine
Laura is an amazing scientist!
Pembrolizumab After Locally Ablative Therapy for Oligometastatic Non–Small Cell Lung Cancer ja.ma/2O5xGif New at @jama Onc-ablation of oligometastatic NSCLC followed by immune checkpoint: OS at 12 mo-90%. Novel and promising application of immune checkpoint inhibition.
Regulatory roles of IL-10–producing human follicular T cells jem.rupress.org/content/early/…
I'm a fan of testing early. Immune therapy more be more effective with less bulky disease.
I'm a fan of testing early. Immune therapy more be more effective with less bulky disease.
Patient page on #CIPN (Chemo Induced Peripheral Neuropathy), in @JAMAOnc w/ @TimothyJBrownMD @ramsedhom #QOL matters. Can be photocopied non-commercially to share with patients. jamanetwork.com/journals/jamao…
Thank you UW CVI #ImmunoOnc19 @UWCancerVaccine
Thank you UW CVI #ImmunoOnc19 @UWCancerVaccine
VERY IMPORTANT COMMENT!!! #ImmunoOnc19 @UWCancerVaccine
Dr. Kandalaft points out that there are many types of antigens that can be used for vaccination, neo antigens of all types- not just point mutations. Target epigenetic changes, phospho Ag...etc. #ImmunoOnc19 @UWCancerVaccine
Dr. Palucka highlights the importance of DC in mediating response to ICI. Recent Immunity paper implicated IFN-g and IL-12 in T cell DC cross-talk. bit.ly/2tHGyxp #ImmunoOnc19 @UWCancerVaccine
Dendritic cells are the most important antigen presenting cells for stimulating T-cell responses to cancer. Nobel Prize winning tumor immunologist Dr. Ralph Steinman was honored for his work in this area. #ImmunoOnc19
Dr. Palucka highlights the issues associated with mutated antigen vaccines; the mutations have to be presented enodogenously in the patients MHC. Most are not. #Immunotherapy #immunoonc19 @UWCancerVaccine
Sounds exciting for endometrial cancer! #ImmunoOnc19
Surely there must be more data supporting a Phase III than just these 20 patients....!!!!#ImmunoOnc19
Surely there must be more data supporting a Phase III than just these 20 patients....!!!!#ImmunoOnc19
Many talks are associating PD-L1 tumor expression with clinical outcome- yet don't tell us definition of PD-L1 positivity. Is it 50%, 5%, 1%? On tumor? On immune "hot-spots"? on APC? Hard to figure out the utility of association. #ImmunoOnc19 @UWCancerVaccine
Vivek Subbiah, MD @VivekSubbiah
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24K Followers 10K Following @nytimes reporter covering prescription drugs [email protected] 714-478-4224 for calls, texts, Signal or WhatsAppJohn P. Leonard, MD @JohnPLeonardMD
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701 Followers 174 FollowingStacy Loeb, MD @LoebStacy
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11K Followers 1K Following Co-founder @synth_labs. Former CEO @Illumina, President @Symantec, GPM @Microsoft. Co-founded IMlogic (acquired by Symantec), & Flash (acquired by Microsoft).Ross Camidge, MD, PhD, and Corey J. Langer, MD, discuss the next-generation EGFR inhibitors rociletinib and AZD9291 ow.ly/Avxji
Agree completely with @DrNDisis. Take a look at the deep TME complexity shown by @VesteinnThors: PMCID: PMC5982584. Will need Systems Biology approaches (wet lab and computational) to understand IO resistance and precision medicine. #ImmunoOnc19
Listening to and seeing the elegant molecular-driven correlative studies in the GU session, I am getting more and more dissatisfied with the classification of cancer as a "hot" or "cold" tumor. #ImmunoOnc19 @UWCancerVaccine
Watch @WingsofKaren founder, @UWCancerVaccine trial participant, @UWMedicine CVI Campaign Development Council member and relentless breast cancer research advocate Kristi Blair share her incredible story: youtu.be/0y2zuw8JOT0 via @YouTube
Swallowed AM dose of crizotinib for ROS1+ NSCLC while sitting in #AACR2018 session about clinical trial designs and value of including small subpopulations. @ros1cancer #lcsm #irony
In Memoriam: Former President and Director of Fred Hutchinson Cancer Research Center, Robert W. Day, MD, Dies at 87 ascopost.com/issues/january…
Does treatment with nivolumab affect the incidence of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR–TKI)-induced interstitial pneumonitis (IP) in non–small cell lung #cancer (NSCLC) patients? Find out in this brief report: ja.ma/2DAMuzs #ImmunoOnc18
Congrats JAMAOnc for inaugural impact factor 16.5 ! Top 10 in Oncology -> next goal top 5 @JAMAOnc @DrNDisis @JAMA_current @JackWestMD
Struggling with #HidradenitisSuppurativa? Check out these resources to get information that can help.
Proud to be working with strong women scientists @IRPatNIH @theNCI @NCIResearchCtr x.com/nciresearchctr…
Kicking off #WomensHistoryMonth with a look at our Women In Science who are leading the way in fight against cancer bit.ly/2mt1qqB
Happy bday, @MountRainierNPS & Mount Olympus National Monument (now @OlympicNP)! Here's how you can celebrate: st.news/2lzlsLd
My idol, another chic, smart #sciencewomen in the TOP!! @laurentzitvogel x.com/drndisis/statu…
Dr. Zitvogel: antibiotics prior to anti PD1 inhibits therapeutic efficacy@@ASCO @sitc #immunosym
Would love to see them refine our ability to predict efficacy of checkpoint inhibs in clinical care vs. PD-L1 express'n alone as control. x.com/drndisis/statu…
@JackWestMD both mutational load and TIL predict outcome. Clear both contribute independently. #immunosym @ASCO @sitcancer
SITC staff proudly wearing white to raise #CancerImmunotherapy awareness & #WhiteOutCancer. #MakingCureaReality
Susan G. Komen Founder Nancy G. Brinker will be in Omaha tomorrow for the Power of Promise Luncheon!
Share this with someone who needs a little encouragement today! #MotivationalMonday
Pos ph 3 trials in #PancreaticCancer predicted by whether earlier ph 2 trials cross higher bar for efficacy spr.ly/6018BSZgi #ASCO16
Have we reached the point where financial toxicity (FAEs) should be reported alongside SAEs during presentations at #ASCO16?
Despite increasing knowledge in the fight against cancer, there is still work to do #ASCO16