Olson Lab @DEOlsonLab
We develop plasticity-promoting neurotherapeutics through a combination of chemistry, molecular/cellular biology, and behavioral neuropharmacology. olsonlab.org Joined September 2020-
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Check out the latest IPN paper in J. Med. Chem. on the development of psychoplastogenic DYRK1A inhibitors with potential for treating Alzheimer's disease especially early-onset Alzheimer's disease associated with Down Syndrome pubs.acs.org/doi/10.1021/ac….
@UCDavisIPN Director @DEOlsonLab talks about psychedelics and nonhallucinogenic psychoplastogens on the @UChicago's Big Brains podcast news.uchicago.edu/psychedelics-w…
IPN director @DEOlsonLab was interviewed for this PNAS news feature on the mechanisms of psychedelics pnas.org/doi/10.1073/pn…
Within #psychedelic science, the debate lingers: Is it mind-blowing experiences or powerful #molecules that spur change? Join @TTBOOK to hear David E. Olson's take. Also available on @Spotify! youtu.be/JunhDmkrM88?si…
The @UCDavisIPN will be sending out their first newsletter soon. If you are interested in #psychedelics or #neurotherapeutics and would like to receive a copy, please sign up by clicking on the link on this page: neurotherapeutics.ucdavis.edu/news-1
Congrats to the Delix team on their positive phase 1 results that they are presenting at ACNP! Also, super excited that Jeff Jonas, former CEO/CIO of Sage Therapeutics, will be joining the Delix SAB! businesswire.com/news/home/2023…
nice article featuring @UCDavisIPN associate director @johnalangray cleveland.com/news/2023/11/a…
article in @TheAtlantic on nonhallucinogenic psychoplastogens: theatlantic.com/health/archive…
our latest review covering the effects of psychedelics on neuronal physiology: annualreviews.org/doi/abs/10.114…
great article by @Sara_Reardon in @Nature about the therapeutic mechanisms of #psychedelics nature.com/articles/d4158…
very interesting article about the role of neuroplasticity in treating depression: wired.com/story/why-anti… Covers a nice @molpsychiatry paper from Gitte Knudsen's group
It's a sad day for psychedelic science. Roland Griffiths was a true pioneer. I still remember exactly where I was when I read his influential 2006 paper: hopkinsmedicine.org/press_releases… He has had an incredibly positive impact on this world, and I'm very lucky to have known him
Check out our most recent paper in @JACS_Au on the total synthesis of tropane alkaloids. This is our first step towards identifying tropane-based psychoplastogens that are better tolerated than molecules like scopolamine. pubs.acs.org/doi/10.1021/ja…
Check out our latest paper in @JOC_OL on ergoline synthesis: pubs.acs.org/doi/10.1021/ac…
This work was led by the very talented PhD student @RunChesterZhang, with help from many more in our lab. A great example of tool engineers and neuroscientists working together. Also thanks to @DEOlsonLab! We're getting plasmids up on Addgene, but reach out if you can't wait! 6/6
How do researchers strip a #psychedelic of its hallucinogenic properties? David Olson (@DEOlsonLab), founding director of @UCDavisIPN, walks us through the chemical evolution of these revolutionary compounds: lettersandscience.ucdavis.edu/news/how-do-yo… #UCDavis #psychedelicscience #mentalhealth
Nice article on the TREAT initiative, which would fund #psychedelic research in california: sacbee.com/news/politics-…
Congrats to @MileHighLab, our longtime collaborator, for receiving an RFS Award! home.liebertpub.com/publications/p…
Could "tripless" #psychedelics be the future of therapy? Discover how these drugs are reshaping #psychiatry while opening new doors for mental health treatments. vox.com/future-perfect… via @voxdotcom
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Groundbreaking research is being conducted on psychedelic drugs and their potential for treating mental illnesses. On @BigBrainsUC, learn how the @DEOlsonLab at @ucdavis is working to make them safer, more effective and accessible to all. ms.spr.ly/6015iWisR
Cheers to Dr. Tina Kim (@tinakim_neuro), a @ucdavisCNS Core Member and IPN Affiliate, on making MIT Tech Review's Innovators Under 35 list! Huge congrats! @ucdavisNC @ucdavis @ucdavisHealth @UCD_Neurology innovatorsunder35.com/the-list/chris…
@AlikWidge @npp_journal Final speaker @TheBorisLab Check out the corresponding #NPPR2024 review with @DEOlsonLab @npp_journal nature.com/articles/s4138…
This work was led by the very talented PhD student @RunChesterZhang, with help from many more in our lab. A great example of tool engineers and neuroscientists working together. Also thanks to @DEOlsonLab! We're getting plasmids up on Addgene, but reach out if you can't wait! 6/6
How do researchers strip a #psychedelic of its hallucinogenic properties? David Olson (@DEOlsonLab), founding director of @UCDavisIPN, walks us through the chemical evolution of these revolutionary compounds: lettersandscience.ucdavis.edu/news/how-do-yo… #UCDavis #psychedelicscience #mentalhealth
Could "tripless" #psychedelics be the future of therapy? Discover how these drugs are reshaping #psychiatry while opening new doors for mental health treatments. vox.com/future-perfect… via @voxdotcom
Loved writing this with @DEOlsonLab - we have some differing views on psychedelics! Thx @npp_journal for giving us the space to explore Qs like how to model the complexity of psychedelic therapy in lab species- more to come!
New review now online - part of @npp_journal reviews 2024 issue #NPPR2024 from Boris Heifets @TheBorisLab and David Olson @DEOlsonLab, "Therapeutic mechanisms of psychedelics and entactogens" nature.com/articles/s4138…
Excited to share the lab's latest #bioinorganic work in @J_A_C_S showing that copper can facilitate complexation of C-peptide and albumin, offering important implications on C-peptide's biological activity and application as a biomarker. pubs.acs.org/doi/full/10.10…
Positive Phase 1 results from a drug invented by @RothLabUNC and Kozikowski lab Discovered by @NIMHgov funded research! brightmindsbio.com/bright-minds-b…
We are thrilled @CRP_Laboratory to celebrate our two-year lab anniversary with news of an NIH MIRA! Thank you to @NIH @NIGMS for this game-changing news!! Time to make the most of it.
Did you hear the news? The first novel psychoplastogen from @UCDavisIPN, @DEOlsonLab and @Delix_tx has recently been administered to human subjects for testing. So far results indicate that it's nonhallucinogenic and well tolerated! Learn more: prnewswire.com/news-releases/… #UCDavis
@ucdavis alum @FredBarrettPhD takes over as the director of the @JHPsychedelics center. Congrats Fred!
The Johns Hopkins Center for Psychedelic & Consciousness Research is pleased to announce the appointment of Frederick S. Barrett, PhD, as its new Director, effective immediately. Join us in congratulating Dr. Barrett on this new role. Press release: hopkinsmedicine.org/news/newsroom/…
I am humbled and honored to follow in the footsteps of such an impactful person, and grateful for the opportunity of a lifetime to lead a world-class team.
The Johns Hopkins Center for Psychedelic & Consciousness Research is pleased to announce the appointment of Frederick S. Barrett, PhD, as its new Director, effective immediately. Join us in congratulating Dr. Barrett on this new role. Press release: hopkinsmedicine.org/news/newsroom/…
IPN director @DEOlsonLab comments on a recent study from the group of @castren_eero about #psychedelics binding to TrkB inverse.com/health/lsd-mag…
Exactly 20 years ago, I started my undergraduate journey at @uclachem. And so I am especially excited (and a bit intimidated) to step into this new role. Lots of big shoes to fill, especially of Neil @GargLab, who masterfully navigated our department through some of the toughest…
Professor Alexander Spokoyny has been named next Chair of the UCLA Department of Chemistry & Biochemistry effective July 1, 2023. chemistry.ucla.edu/news/alexander… @organomimetic @uclaphyssci @UCLAnewsroom
Please check our latest paper nature.com/articles/s4159…. LSD and psilocin are high-affinity ligands of TrkB, sensitizing TrkB to BDNF, promoting plasticity, but not hallucinations. Huge thanks to all the co-authors, especially @RafaelMoliner, @p_casarotto and Ilpo Vattulainen.
Founding director of the newly-formed @UCDavisIPN and now a Rising Star. This is who we are ... spr.ly/6012O9ghO
Would like to thank @purduepharmacy @Purdue_MCMP for the recognition, the Chaney family for making the award possible and the awesome members of @FlahertyLab for making this possible. They are the ones who earned this award.
Dr. Daniel Flaherty, assistant professor of medicinal chemistry and molecular pharmacology, is the 2023 Chaney Family Early Faculty Scholar. Congratulations! ow.ly/hWPT50OlZIU #pharmacysgiantleap
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