Tim Blower @BlowerLab
Senior Principal Investigator at New England Biolabs and Honorary Professor at Durham University. Views my own. He/him. blowerlab.com New England Biolabs, MA Joined September 2020-
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Phages invented sgRNAs before humans!! Obviously, for mischief… 😈 Loved seeing this story unfold! biorxiv.org/content/10.648…
NEB researchers systematically screened 186 MazF homologs, identifying >130 active endoribonuclease with diverse sequence preferences. Read more about how Tth-MazF1 can be a powerful tool for RNA analysis in Nucleic Acids Research: doi.org/10.1093/nar/gk…
Rejection is part of science. So is resilience. 🔬 @BlowerLab and @CJStewart7 share how setbacks helped shape their careers. We don't talk about this enough. 🔁Please repost and share your own stories of defeat or bouceback. Break the stigma! lister-institute.org.uk/news/resilienc…
Postdoc position now open in my lab at New England Biolabs. Focus is on exploring phage defence systems through biochem and structural biology. @NEBiolabs provides an academic research environment with the freedom of industry. Please take a look! 🤓🧫🧬 tinyurl.com/49phcyh6
Rel/Par superfamily toxins have yet another activity - trimming off the 16S rRNA to kill tuberculosis. Thanks again to wonderful collab with @GenevauxPierre and team, out today shorturl.at/Rm8N4 @DurBiol @NEBiolabs @izaakbeck 🤓🎊🎉
Looking for great PhD candidates! Excited to collab with Prof Mark Szczelkun at Bristol UK, studying MADS phage defence. This will be a CASE studentship including research visits to New England Biolabs HQ in MA, USA 🤓 @NEBiolabs shorturl.at/KZGup deadline 3rd Dec
RptR is a new addition to the growing collection of phage defence-associated transcriptional regulators. Congrats to @YugengZ @TangLabOxford @_MarionSchuller @IvanAhelLab and thank you, it was a pleasure to help out the study! @NEBiolabs. academic.oup.com/nar/article/53…
@joeBondyDenomy @DarrenSmithdx @NAR_Open @NEBiolabs @DurBiol Yup great question - working on it!
Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs @DurBiol academic.oup.com/nar/article/53…
We are delighted to host Professor Tim Blower @BlowerLab as keynote speaker to our MID symposium @WarwickLifeSci Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to @CRodriguesLab
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
The post will be based in Ipswich, MA, north of Boston. Non-US citizens welcome (if eligible for a J-1 visa). The focus will be on basic research leading to publications. We provide an academic research and training environment, with >20 research labs.
The lab is now up and running at New England Biolabs @NEBiolabs! I'm looking for a postdoc to study phage defence systems. If you'd like the academic freedom to publish but the resources of industry, then take a look 🤓😃 neb.wd5.myworkdayjobs.com/en-US/NEB_Care…
Super opportunity to join Giusy in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
New pre-print from the lab, led from (for now Twitter-less) star-RA Tom Cummins. If you did receive his PhD application, you do not want to miss this chance, Tom is a star! As always, fun collaboration with the amazing @BlowerLab and @StephenRG97
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow @UofGSii ! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date). @JohnInnesCentre @DurhamU34989 @MCB_UJ
Thrilled to share my latest postdoc paper published in @NatureComms NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors, @GenevauxPierre @BlowerLab @ONeyrolles rdcu.be/dZle4
When experiments don’t work... build a phage costume! 🎃 Happy PHAGEOWEEN!!! 👻🧬#Teamwork
journals.asm.org/doi/10.1128/jv… Our thoughts on how toxins bound to TAs are activated: via conformation changes, not by selective degradation of ATs by a protease (makes little sense since both are structured). Remarkable insights determined by studying various TAs as they inhibit phage.
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412 Followers 132 Following Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo Kashiwa, Chiba 277-0882, Japan
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207 Followers 97 Following Senior Research Associate, @SorekLab, @WeizmannScience, the phage-host arms-race
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296 Followers 924 Following Postdoctoral researcher at Imperial College. Cryo-EM, secretion systems, phages and AMR 🦠🏳️🌈 https://t.co/qlfA3e5uWa
Graham P Stafford @GrahamPStafford
472 Followers 122 Following Biological polymath. Love bacteria, enzymes, bacteriophage, glycans, genes and stuff. Based at @sheffielduni Dental school.
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101 Followers 230 Following Postdoctoral @GDSC_Sussex University. Genome organisation and DNA repair at nuclear periphery with @EviSoutoglou
Andreas Schallmoser @SchallmoserA
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PacBio @PacBio
45K Followers 3K Following Our mission is to enable the promise of #genomics to better human health by creating the world’s most advanced #sequencing technologies. #PacBio
Julia Willett @jlewillett
2K Followers 1K Following #newPI in Micro & Immuno at U Minnesota. Bacterial interactions/biofilms/uncharacterized genes/T7SS. I like wine, traveling, cats, & the LA Kings. She/her.You might like
