BigBiology @Big_Biology
@MartinlabUSF, Art Woods, and @CGhalambor talk to scientists about the biggest questions in biology, evolution, climate, ecology, disease, genetics and more! link.chtbl.com/zgBwQvZr Joined October 2017-
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⭐️We are on Mastodon!⭐️ 🔗 In case you didn’t know, you can find us on Mastodon: @BigBiology@Mastodon@Social 👥Go give us a follow. We’d love to connect! mastodon.social/@bigbiology #mastodon #science #biology #science_communication #sciencecommunication #scicomm
Loved this @Big_Biology episode over some weights. As a bonus—an insight that'll help my students analyse their IB bio investigation (IA). Phenotypic variation'll be small at extremes—as all have passed a threshold. Bio teachers: Listen, follow, support. bigbiology.org/episodes/2023/…
I LOVE when Biology and Art come together. 😍
I LOVE when Biology and Art come together. 😍
As usual, an interesting episode of @Big_Biology, with @MartinlabUSF and Art Woods interviewing @philipcball about his new book "How Life Works" and discussing agency and purpose in evolution podbean.com/ea/dir-5f3gk-1… A thread with a few thoughts 1/n
The science podcast that does not patronize you…. Just the best.
The science podcast that does not patronize you…. Just the best.
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24K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' https://t.co/Sy1rcWXGLz @nightsciencepod@CMooreAnderson @Big_Biology Could it be the one about phenotypic plasticity? Episode 112 - The Entangled Organism. (One of my favorites by the way, though I have to catch up to episodes.) Maybe Episode 104 (Sleeping beauties...)? Didn't listen to that one yet but it does seem to match.
Hey @Big_Biology fans! Can you remember which episode it was in which two types of variation were discussed: Standing variation like a buffet, and variation that comes sequentially, like in a sushi restaurant with those conveyor belts ???
Loved this @Big_Biology episode over some weights. As a bonus—an insight that'll help my students analyse their IB bio investigation (IA). Phenotypic variation'll be small at extremes—as all have passed a threshold. Bio teachers: Listen, follow, support. bigbiology.org/episodes/2023/…
@CMooreAnderson @Big_Biology Reserving this for my walks. 🙂 I think I'll be catching up on episodes all week!
I LOVE when Biology and Art come together. 😍
🔦✨Episode Art Spotlight✨🔦 🎨 Keating Shahmehri showing us their creative process for our latest episode: Biology as its own metaphor (@KorionArt ). 👚Hop on over to our @redbubble store to check out our merch options! (1/2)
@EvolOdonata @Big_Biology @MartinlabUSF It's the organisms that are the agents, remember - there's no "agency" within the evolutionary process!
@EvolOdonata @Big_Biology @MartinlabUSF And I don't ascribe any agency or purpose at rhe "molecular level". What seems to be required for agency simply can't develop at that fine a grain, it seems to me. So I don't see anything "seemingly purposeful" about what proteins are like. The kind of complexity that...
@EvolOdonata @Big_Biology @MartinlabUSF ...seems to become possible from (among other things) intrinsically disordered proteins might very well arise from neutral drift, as Mike Lynch suggests. But that's a different issue.
@philipcball @EvolOdonata @Big_Biology @MartinlabUSF Been thinking about these maple seeds a lot lately. The structure is clearly evolved. It channels local environmental dynamics to suit the 'goal' of dispersion, but it's not an 'active' system🤔 Do passive structures like this fall within a theory of agency?
@philipcball @EvolOdonata @Big_Biology @MartinlabUSF Some synthetic structures to blur the lines a bit more..😊 nature.com/articles/s4158…
@CAS_mitolab @EvolOdonata @Big_Biology @MartinlabUSF I'm not sure how it could. It simply seems adapted for a goal. In that respect, is it any different from, e.g. a sea shell or egg shell? (I'm thinking of things that can serve their function when separated from the organism that produced them.)
@philipcball @EvolOdonata @Big_Biology @MartinlabUSF Thanks! That's fascinating. Does a 'goal' have a lifetime🤔... Thinking about analogy between the maple seeds and biomacromolecules.. Would you say the macromolecules are also simply adapted for a goal? If agency is on a spectrum, is there a lower bound?
@CAS_mitolab @EvolOdonata @Big_Biology @MartinlabUSF Great question(s)! Yes, I think biomacromolecules are simply adapted passive entities. As for a lower bound: my book How Life Work touches on that. I'd say viruses, for example, acquire agency in a host (but there again, they have to infect it in the first place, so...).
@CAS_mitolab @EvolOdonata @Big_Biology @MartinlabUSF That, of course, is the only thing that matters 😉
@philipcball @EvolOdonata @Big_Biology @MartinlabUSF So agency is a statistical (or emergent) property of goal adapted forms? That does seem a bit circular😅 Either way, I'm sold, and will buy your book straight away. Cheers🍻
What needs to be explained is ADAPTIVE complexity. It is only for such complexity that it would be justified to talk about "agency" or "purpose", although I am personally not convinced we gain much from replacing "adaptive phenotypic plasticity" with these new terms 12/
Complexity in itself does not necessarily need to be "purposeful" or in need of any particular adaptive explanation, because it can arise even in the absence of natural selection. This is important to remember to avoid going in to adapationist trap and see purpose everywhere 11/
This is also called "the drift-barriär hypothesis", and is a good argument for not assuming that organismal or molecular complexity per se necessarily need to have some "purpose". On the contrary, a lot of complexity can accumulate by purely passive neutral processes 10/
Lynch shows that the lower genetically effective population size (Ne) of multicellular eukaryotes means that the efficiency of natural selection is weaker than in unicellular prokaryotes, meaning that purely neutral molecular complexity will build up easier in the former 9/
Population geneticist Mike Lynch - one of the strongest and best proponents of Neutral Theory - have made exactly this point in this famous and rethorical masterpiece from 2007: pnas.org/doi/full/10.10… 8/
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