Aram Chung @ac467
Prof at Korea Univ / Co-founder & CEO of MxT Biotech aramchung.com Seoul, Republic of Korea Joined October 2010-
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Following215
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Aram Chung retweeted
Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors go.nature.com/4atBJML
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Aram Chung retweeted
In cancer, activated T cells release abundant extracellular vesicles that transfer DNA to the nucleus of tumor and immune (dendritic) cells, turning tumors from cold to hot. An immunotherapy in the works. @Cancer_Cell sciencedirect.com/science/articl… sciencedirect.com/science/articl…
Aram Chung retweeted
CAR-X cell engineering dlvr.it/TSG6WV
Aram Chung retweeted
A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery go.nature.com/4ugPm9D
Aram Chung retweeted
Macrophage senescence is a central driver of chronic inflammation in aging and metabolic liver disease, and a tractable therapeutic target.
Aram Chung retweeted
In the latest issue! Hallmarks of cancer—Then and now, and beyond dlvr.it/TS4Plc
Aram Chung retweeted
A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery #NBTNV go.nature.com/4s4X7P7 rdcu.be/fdfzQ
Aram Chung retweeted
Steady progress towards engineering immune cells in the body now for refractory myeloma , with major implications for many autoimmune diseases and cancers nature.com/articles/s4159… nature.com/articles/s4159…
Aram Chung retweeted
For readers interested in lipid nanoparticles for oligonucleotide delivery, here's an article covering 60 years of progress in the field rdcu.be/fb9xD nature.com/articles/s4157…
Aram Chung retweeted
Cell senescence and how it predisposes to cancer, no less how we may be able to modulate it. An outstanding @CellCellPress review cell.com/cell/fulltext/…
Aram Chung retweeted
Glad to share our new Nature Chemical Engineering article on new mechanisms for nanocarriers ! nature.com/articles/s4428…
Aram Chung retweeted
Optimized mechanical stimulation provides a simple and effective strategy to counteract age-related bone deterioration and systemic inflammation nature.com/articles/s4146… @NatureComms 🇨🇳
Aram Chung retweeted
Microfluidic Mechanical Reactivation of Aged Stem Cells biorxiv.org/content/10.648…
Aram Chung retweeted
By hitching a ride on the body’s own red blood cells, a new delivery platform for in vivo CAR myeloid cells can bypass immune surveillance and efficiently deliver mRNAs to splenic immune cells for cancer #immunotherapy in mice. @Westlake_Uni scim.ag/48bzwV0
Aram Chung retweeted
Studies of uterus transplant recipients reveal how immune cells shape pregnancy outcomes, an amino acid cocktail enhances nanoparticle delivery of therapeutic mRNAs in mice, and more this week in #ScienceTranslationalMedicine. scim.ag/3NgmFcX
Aram Chung retweeted
"Safe and Efficient CRISPR Genome Editing of Primary Human T Cells Using a Droplet-Based Cell Mechanoporation Platform" Kim YJ, Bang S, Chung AJ. Small. 2026-02-05. doi.org/10.1002/smll.2… ... achieving up to a 2.35-fold higher efficiency than electroporation.
Aram Chung retweeted
Now online! A post-assembly, reversible crosslinking strategy that enhances lipid nanoparticle-mediated mRNA delivery while preserving efficient intracellular release. Link ($): nature.com/articles/s4428… Free PDF: rdcu.be/e4elc
Aram Chung retweeted
Eleven clinical trials that will shape medicine in 2026
Aram Chung retweeted
Our editors pick their favorite research articles from 2025 go.nature.com/4oCK84L
Aram Chung retweeted
CAR-T and NK cells engineered using a non-viral circular single-stranded DNA system show effective anti-tumor function go.nature.com/3ZLpoPb rdcu.be/eRy0K
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