Yang Yang @yang2biocat
Assistant Professor @UCSB. @Buchwild_Group @francesarnold group alum. Advancing radical biocatalysis to shed light on synthesis, catalysis, and enzymology yang.chem.ucsb.edu Santa Barbara Joined September 2019-
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Our paper on evolved nonheme Fe enzyme ACCO for stereoselective fluorine atom transfer is online at Nature Synthesis: nature.com/articles/s4416…
It is my greatest pleasure to become a Sloan Research Fellow this year! I am grateful to my group who did all the work and my nominators who supported my application. Looking forward to accomplishing more in biocatalysis, enzyme design and enzyme engineering!
It is my greatest pleasure to become a Sloan Research Fellow this year! I am grateful to my group who did all the work and my nominators who supported my application. Looking forward to accomplishing more in biocatalysis, enzyme design and enzyme engineering!
Rmc cyt c can make C-Si bonds, now an engineered P450 can break C-Si bonds!
Rmc cyt c can make C-Si bonds, now an engineered P450 can break C-Si bonds!
Thank you for the highlight, @angierangeles! The DOC GRS was a great experience and I really enjoyed talking to fellow graduate students and faculty at the symposium held in Austin, Texas back in 2015.
Thank you for the highlight, @angierangeles! The DOC GRS was a great experience and I really enjoyed talking to fellow graduate students and faculty at the symposium held in Austin, Texas back in 2015.
It is my greatest honor to be selected as a Packard Fellow this year @PackardFdn @ucsbchemistry! I look forward to further growing our program and developing new biocatalytic reactions that are not known in organic chemistry and biochemistry packard.org/insights/news/…
Exciting new method for deracemization!
Frances Arnold @francesarnold
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171 Followers 239 Following Assistant Prof. of Chemistry @PurdueChemistry, Purdue Institute for Integrative NeurosciencePublished today in @NatureCatalysis : nature.com/articles/s4192… @francesarnold
Today we report in @ChemRxiv a biocatalytic strategy for enantioselective amination of 3° C–H bonds, providing chiral α-tertiary primary amines with up to >99% e.e., all in challenging intermolecular and notorious Me–Et substituted settings, w/o DGs chemrxiv.org/engage/chemrxi…
We verified the function of a C–S bond forming P450 in griseoviridin biosynthesis for the first time and developed a short chemoenzymatic synthesis of the natural product: chemrxiv.org/engage/chemrxi…
They're trying to distract us from the ICML 2024 decisions!
ICML 2023 conference videos are available here: slideslive.com/icml-2023
I wrote about @ritter_lab's One Weird Trick (nitrate reduction) for less explodey diazonium chemistry: cen.acs.org/safety/lab-saf…
We are proud to announce renowned biochemist Hening Lin will join the University of Chicago Department of Chemistry. Lin will serve a primary appointment in @UChicagoBSD, with a secondary appointment in @UChiChemistry as a Professor of Chemistry. chemistry.uchicago.edu/news/renowned-…
Stereoselective amino acid synthesis by #photobiocatalytic oxidative coupling by Tian-Ci Wang, @khanhbinh183, Zheng Zhang, Zhiyu Bo, Jiedong Li, @pengliu_group, and Yang Yang @yang2biocat in @Nature nature.com/articles/s4158…
It was such a great day hosting @yitang_ucla and Bill Gallagher (BMS) @EmoryChem yesterday! Incredible science happening in academia and industry!
Congratulations to the eHAT team on the newest publication out today in @J_A_C_S, led once again by the terrific collaboration between @ChengChem and Luke from the @PrattGroup @maldonadogroup @StephensonLabUM pubs.acs.org/doi/10.1021/ja…
Now online: Article by Peng Liu, Yang Yang and co-workers @pengliu_group @Pitt_Chemistry @yang2biocat @UCSB Biocatalytic enantioselective C(sp3)–H fluorination enabled by directed evolution of non-haem iron enzymes nature.com/articles/s4416… ($)
I am deeply grateful to @dreyfusfndn for this esteemed recognition. My sincere thanks to all current and former members of our team for their dedication and hard work, which have made this possible.
Congratulations to Dr. Xiongyi Huang (@xiongyih), @JohnsHopkins, for being named a 2024 Camille Dreyfus Teacher-Scholar! @JHUChemistry #DreyfusAwards
Congratulations to Assistant Professor Monica Neugebauer (@NeugMonicaElena), who is a 2024 recipient of the Shaw Early Career Research Award! The $200,000 award is sponsored by @GrMKEFdn. Learn more about Neugebauer's research: biochem.wisc.edu/2024/04/24/neu…
Attenuating N-Oxyl Decomposition for Improved Hydrogen Atom Transfer Catalysts (Corey R. J. Stephenson and co-workers) @crjsteph @maldonadogroup @PrattGroup #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
Happy to share the final version of our work describing computational filters for selecting functional ML-generated enzymes in @NatureBiotech! This was a distributed and remote collab with @TrichomeDoctor @Xiaozhi_Fu and other members of @AZelezniak's group. Global Science!
Our computational filter for enriching functional AI-generated enzymes is finally out. nature.com/articles/s4158… Many thanks to @TrichomeDoctor @KevinKaichuang @Xiaozhi_Fu et al. for the fantastic collaboration!
Self-recycling imine reductases? Yes please! Congrats to the Novartis team for turning a promiscuous Glucose Dehydrogenase into an IRED #biocatalysis #proteinengineering #greenchemistry | ACS Catalysis pubs.acs.org/doi/10.1021/ac…
The next chapter of our metal catalysis work is now on @ChemRxiv. We report that an unusual reversible Pd "ring-walking" process can be used to access unconventional isomers of cross-coupling products! doi.org/10.26434/chemr…
Something new in #biocatalysis: using an engineered flavoprotein oxidase, we could perform oxidative aminations! and more... doi.org/10.1002/cctc.2…
Super happy to receive this award 🎉! Huge thanks to my wonderful group, the selection committee and the supportive environment @EuroMedChem @NCCR_Catalysis @ZHAW Looking forward to presenting our science at the EFMC-ISMC conference in Rome! efmc.info/prizes
I'm sad to hear that Sergey Berdonosov passed away today. He was a true luminary in chemistry education and nuclear chemistry research in the USSR/Russia, and many of us owe our careers to him. As a researcher and faculty member at Moscow University, he spearheaded a specialized…
I would like to express my gratitude to my collaborators, @MarcGBQ and Prof. Yunfang Yang from Zhejiang University of Technology, for their valuable contributions to this project.
Both my group and Yang's group @yang2biocat have demonstrated that nonheme iron enzymes can be engineered for enantioselective C(sp3)-F bond formation via iron-mediated radical fluorine transfer. Huge congratulations to the team led by postdoc Qun Zhao @qun_zhao , now a professor…