Sonya @sonyahans
Research Scientist @FlatironInst | biological temperature sensors 🌡️ cryo-EM 🔬computational biophysics 👩🏼💻 https://t.co/5fO6ikXBZo sonyahanson.com Joined August 2010-
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Super excited to have this preprint lead by @jayrshenoy out for people to see! Exciting work!
AlphaFold-based models like Boltz-2 and BioEmu train on atomic conformational structures in order to predict protein dynamics. But is it possible to train these models directly on cryo-EM map ensembles, harnessing conformational data that is typically not deposited in the PDB?
AlphaFold-based models like Boltz-2 and BioEmu train on atomic conformational structures in order to predict protein dynamics. But is it possible to train these models directly on cryo-EM map ensembles, harnessing conformational data that is typically not deposited in the PDB? Introducing CryoSampler: a new approach for fine-tuning Boltz-2 with raw supervision on cryo-EM map ensembles. 1/6🧵
Super proud of @PolymathicAI 's new foundation model on biomolecules! 🚀 It was probably the most challenging datasets 💪 we have gathered so far (which we are making public!) and realizing biology is super hard even when you work with the best domain scientists @PilarCossio2 @sonyahans @JonesyLab & @OlgaTroyanskaya Hats off to the team led by @SiavashGolkar J.Kovalic @irina_espejo , @samsledzieski & @mhli41 !
1/12 Introducing MIMIC: a SOTA foundation model trained natively across DNA, RNA and proteins. MIMIC is multimodal and generative: it can use structure, regulation, evolution, and experimental context to infer missing biology or design new sequences.
Postdoc job opening! This is a unique opportunity to work at the intersection of computation of experiment between us at the Flatiron and a time-resolved cryo-EM lab at the Crick: crick.wd3.myworkdayjobs.com/External/job/L… Deadline May 6.
Celebrating #BiophysicsWeek T&C partnered with Phase Space Invaders podcast: Robert Best @sonyahans @XuhuiHuangChem and host @MiWieczor Episode 32: Driving the Future of Biophysics: What’s Next in Theory and Computation? buzzsprout.com/2313153/episod…
If you're not on the multi-thousand-person cryo-EM listservs... we (EZ lab @PrincetonCS, @FlatironInst, #CCPEM) just announced a new #heterogeneity challenge for cryo-EM! #CAHRA2025 Webinar this Fri Nov 14 at 12p ET. Datasets and more info here: heterogeneity.notion.site/challenge We've been preparing this challenge for over a year 🥵 (designing the heterogeneity, collecting data, validating results and metrics). Super excited to finally share it with the community! There are three mystery❓❔❓ datasets! Some fun facts about each: 1) comp-het: an experimental dataset containing a mixture of mystery❔complexes 2) conf-het: we're asking folks to submit *atomic models* instead of density maps for the first time ❗️❕ 3) pose-entanglement: a simple dataset to test how much the pose distribution influences conformation estimation 🐎 Huge shoutout to the members of my group driving this work @FeathersRyan and Robert Heeter, @sonyahans + @PilarCossio2's groups @FlatironInst, and Joel Greer from Tom Burnley's group at #CCPEM. Calling both methods developers and users to participate! Check out our website for more details!
@IrinaBezsonova @buildmodels This is so cool! Love that you do this! Have you done a TRP channel?
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge
Last week, #FlatironCCM and #FlatironCCB held a Computational Cryo-EM Workshop that focused on methods for 3D heterogeneity analysis including deep learning and statistical techniques in cryo-EM. #science #biology #math
Check out our latest preprint for the first community #cryoEM heterogeneity challenge 🎆🎇 @sonyahans @miroastore + method developers and participants!
That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv! biorxiv.org/content/10.110…
That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv! biorxiv.org/content/10.110…
Interested in pursuing graduate studies in Biophysics at U-M? We're inviting prospective students to explore our program hands-on! We're now accepting applications for the Biophysics Graduate Preview Program on October 23-24, 2025.📅 Learn more & apply: lsa.umich.edu/biophysics/gra…
Come work with us on advancing science using LLMs! Exciting times ahead 🧑🔬🤖
We are expanding our efforts in LLM-based scientific discovery and are hiring for several roles. Come join my team and work with us on the future of natural language scientific AI! job-boards.greenhouse.io/deepmind/jobs/… job-boards.greenhouse.io/deepmind/jobs/… See RS and RE roles above.
📣 Calling all Rising Stars in Biological Engineering. Nominate someone or self nominate: forms.gle/EszC1AvRFpfN1G…
@IsraelF96135088 Thanks @IsraelF96135088 . Building on lots of other people's work here, and still a work in progress, but excited to publicize more broadly that we are working on this!
Registration is now open for our Benzon Symposium on "Protein structure prediction and design" Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and will feature an amazing list of speakers Get your application in before March 31st!
📣 Save the dates 📅 We are organizing a Benzon Symposium on "Protein structure prediction and design" with what I think is an amazing set of speakers Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and abstract submission will open in March
We are hiring a Flatiron Research Fellow in the Structural Molecular Biophysics team! Experience with cryoEM and/or membrane protein simulations are a plus! Happy to chat in person with anyone at #bps2025 ! apply.interfolio.com/160227
Excited for #bps2025! Check out what SMBp has been up to at these talks and posters! (Also follow me at the other place.) @miroastore @samsledzieski @a_anand_ojha
We're looking for Research Engineers to work at the intersection of LLMs and impactful scientific problems! Applications close next Tuesday 18th. Link to job ad in thread.
Andrew White 🐦�... @andrewwhite01
33K Followers 2K Following Automating science. Cofounder @EdisonSci. Cofounder @FutureHouseSF. Prof of chem eng @UofR (on sabbatical).
Max Planck Institute ... @MPIbp
6K Followers 418 Following Our research concerns biological membranes with particular emphasis on the structure and function of membrane proteins. #Biophysics #cryoEM #structuralbiology
Kevin K. Yang 楊凱�... @KevinKaichuang
23K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
Amelie Stein @_amelie_rocks
2K Followers 3K Following Assoc Prof @ U of Copenhagen. Better at plots than blots. ❤️ proteins, strong feelings about many others things, too. Trying to listen & learn. She/her.
Caroline Lynn Kamerli... @kamerlinlab
8K Followers 6K Following Prof @GT_Chem @ga_res_alliance Eminent Scholar. Pianist, photographer, foodie, dreamer, mom. She/they. #FirstGen #MENA ❤️☀️💚 All views my own.
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Lukas Stelzl @l_stelzl
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Brady Johnston @bradyajohnston
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Ariane Nunes Alves @anunesalves
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JCIM & JCTC Journals @JCIM_JCTC
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Chemjobber @Chemjobber
45K Followers 5K Following 1. A blog 2. Towards a quantitative understanding of the quality of the chemistry job market | #chemjobs: permanent industry/academia, #chempostdoc: postdocs
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Rebecca Thompson @Bex_16
3K Followers 2K Following All things #CryoEM #ElectronMicroscopy #VolumeEM @thermosciEMSpec She/her. Opinions definitely my own.
Aanuoluwapo @abidoye_sa88310
58 Followers 4K Following UG @ OAU|Computer vision|Multimodal learning|Foundation models
Ash @arshiailaty
510 Followers 6K Following PhD @UCIrvine & @SDSU | EX-SWE-intern@Tesla گورستانِ ماه است شب!
Yu Tin Lin @YuTinLin3
91 Followers 831 Following Striving to be non-striving, nonjudgmental of judgements, & mindful of mindlessness
Aristotle @Aristotleqe
10 Followers 1K Following Figuring it out, sometimes you’ve got to run before you can walk. 🤞🏽
conan kinde @ConanKinde
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Veritas @Veritas004
195 Followers 6K Following
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364 Followers 352 Following Founder at @Exonicai (YC F25) AI for precision gene therapy.
George @Geo_Eid_
543 Followers 3K Following @Northeastern Physics grad student who is interested in philosophy/theology
keshav Kant @keshavvkant
375 Followers 7K Following A fractal mind, trying to find self similarities in the world. MSc biology'24 @AshokaUniv
Joel TorresV @TorresvJoel
140 Followers 386 Following Microbiology & Parasitology. I'm love Structural Biology, Bioinformatic, and Drugs discovery.
Gourav choudhir @gouravchoudhir
167 Followers 1K Following I am a researcher. Equally love for science and coffee. Disability In Stem
@[email protected] @l_II_llI
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Minhuan Li @mhli41
157 Followers 178 Following CCM @ Flatiron Institute, Prev. PhD @ Harvard | Grounding generative AI in rigorous biophysical principles.
Jackson Carrion @jacksonnn18
220 Followers 589 Following Computational & Systems Biology PhD student @MIT #cryoEM #AI
Alessio Zaccone 🇺�... @ZacconeAlessio
2K Followers 1K Following Full Professor of Physics at Uni of Milan, Italy & Gauss-Professor at Uni Göttingen, Germany. ERC Consolidator grantee. Former professor at Uni of Cambridge.
Michael McLean @mklmclean
78 Followers 240 Following Research Engineer at @structurabio | Engineering Physics graduate from @UofT | he/him
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0 Followers 1K Following
JHU CLSP @jhuclsp
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Svetla McPhie @svetlamcphie
28 Followers 367 Following CryoEM and structural biologist. Passionate about nature and knowledge. There is always a new horizon to reach.
deMarcoLab @demarco_lab
375 Followers 164 Following Developing methods while breaking expensive equipment
Henry Mattingly @HenryHMattingly
197 Followers 240 Following Biophysics, information processing, collective behaviors. Associate research scientist at @FlatironInst. Views are my own.
Cristina Gutierrez-Va... @CristinaGVx
7 Followers 71 Following
Hannah R Bridges @HannahRBridges1
419 Followers 340 Following Biochemist and Structural Biologist|Cryo-EM Application Scientist at @structurabio|Amateur artist|All views my own|https://t.co/2cdXrKVKJe
Taha Shahid @taha_shahid
28 Followers 160 Following
Rashmi Panigrahi @PanigrahRashmi
33 Followers 309 Following
Madhuri kanavalli @Madhuri_52
94 Followers 476 Following Doctoral student @ CNBCh, University of Warsaw. #StructuralBiology #ProteinInteractionStudies #CryoEM #DrugDiscovery
Giulia Palermo @palermo_lab
4K Followers 2K Following Giulia Palermo Lab at the University of California, Riverside. Biophysicist passionate about Science & Art!
Acta Physico-Chimica ... @ActaPhysChimSin
569 Followers 6K Following Acta Physico-Chimica Sinica (IF = 13.7), a journal from Chinese Chemical Society @ChineseChemSoc and Peking University @PKU1898, focusing on #Physical_Chemistry
StockMoverNews🇺�... @Oobuide43232
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Zhi Z @ZhiZ332518
0 Followers 35 Following
Katarina Elez @ElezKatarina
115 Followers 197 Following PhD student in Bioinformatics at @FU_Berlin | Drug discovery, ML and molecular simulations | 🧑💻
Alex Page @aPageofideas
450 Followers 5K Following Anaesthetics registrar 💉 ICU inclined 🫁 FRCA 💪 UK trained 🫖 San Francisco 🌈 Physiology fanatic 🫀 ever curious 📚veteran tree-climber 🤸 She/her
Serena Arghittu @serena_arghittu
30 Followers 127 Following
Maria V. Carreira @MariaVCarreira
31 Followers 349 Following PhD Student @MIT | ML in Structural Biology | BSc @ucl
FoldingCoin @FoldingCoin
11K Followers 286 Following Help Stanford University's Folding@home with your extra computing power and earn tokens for work completed. Join the community at https://t.co/WcnX9pXhZr
Kaitlyn Abe @kaitlyn_m_abe
85 Followers 102 Following Biophysics Grad Student @ UW Madison in the Lim Lab || UC Davis Alumn
Bohrium @Bohrium_AI4S
893 Followers 116 Following Bohrium- AI for Science with Global Scientists! Join our Discord: https://t.co/Q6quPHZIu7 Follow us: https://t.co/fnkK3q2Qxq
Ropón-Palacios G. ت... @roponpallab
423 Followers 2K Following I'm a research programmer and computational biologist/biophycisist working into understading complex biological phenomena. My tweet, my own opinion. #NTDs
Andrew White 🐦�... @andrewwhite01
33K Followers 2K Following Automating science. Cofounder @EdisonSci. Cofounder @FutureHouseSF. Prof of chem eng @UofR (on sabbatical).
Kresten Lindorff-Lars... @LindorffLarsen
15K Followers 2K Following Protein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
Max Planck Institute ... @MPIbp
6K Followers 418 Following Our research concerns biological membranes with particular emphasis on the structure and function of membrane proteins. #Biophysics #cryoEM #structuralbiology
Frank Noe @FrankNoeBerlin
13K Followers 567 Following Scientist, #MachineLearning and #AI for the Sciences (esp. Physics/Chemistry). Scuba Diver and Traveler.
Ardem Patapoutian @ardemp
51K Followers 263 Following @scrippsresearch Professor. @HHMINEWS Investigator. @NobelPrize 2021. Research: touch & other forms of pressure sensing. Find me at @ardemp.bskyverified.social
Frances Arnold @francesarnold
86K Followers 778 Following Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)
Sjors Scheres @SjorsScheres
15K Followers 1 Following This account is no longer in use. Follow our science on: https://t.co/mlxULCj9zl
Kevin K. Yang 楊凱�... @KevinKaichuang
23K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
Sergey Ovchinnikov @sokrypton
18K Followers 4K Following Scientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦 No Human is illegal. Moving to: https://t.co/sow6IRD3jj
Amelie Stein @_amelie_rocks
2K Followers 3K Following Assoc Prof @ U of Copenhagen. Better at plots than blots. ❤️ proteins, strong feelings about many others things, too. Trying to listen & learn. She/her.
Karen Fleming @KarenFlemingPhD
6K Followers 460 Following Scientist & Professor @JohnsHopkins - I work in discovery to fill the scientific pipeline. #ScienceIsReal Views are my own. Advocate for #WomenInSTEM
Caroline Lynn Kamerli... @kamerlinlab
8K Followers 6K Following Prof @GT_Chem @ga_res_alliance Eminent Scholar. Pianist, photographer, foodie, dreamer, mom. She/they. #FirstGen #MENA ❤️☀️💚 All views my own.
Olexandr Isayev 🇺�... @olexandr
10K Followers 4K Following #CompChem Prof @CMU_Chem. Connecting chemical sciences with AI & #MachineLearning. #tarheels fan. Care:#design, #photography #Ukraine #cats🐈 Rants are mine
Lorenzo Casalino @LCasalino88
1K Followers 693 Following Assistant Project Scientist | @RommieAmaro's lab, @UCSanDiego. Computational biophysicist.
Patrick Walters @wpwalters
6K Followers 375 Following cheminformatics, machine learning, drug discovery, opinions
Greg Bowman @drGregBowman
9K Followers 1K Following Imperfect Christ-follower desperately searching for truth, especially through science. Prof @Penn. Director @foldingathome. Legally blind. Father
John Chodera (he/him) @jchodera
9K Followers 7K Following Changing drug discovery one ratio of partition functions at a time. Heading up antiviral discovery for pandemics: https://t.co/uN4XpX1mjt https://t.co/YAg9PBYuBl
Lukas Stelzl @l_stelzl
1K Followers 1K Following Disordered proteins, nucleic acids and their dynamics complexes & condensates. Integrating simulations and experiments.
Brady Johnston @bradyajohnston
17K Followers 2K Following 🐘: [email protected] ⛅️ @bradyajohnston struc. biologist, scientific animator, creator of #MolecularNodes, he/him #rstats #b3d
Dan Minor @ElectrosomeUCSF
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Gordon Wetzstein @GordonWetzstein
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Xuhui Huang @XuhuiHuangChem
2K Followers 825 Following Hirschfelder Chair, Professor of Chemistry @UWMadisonChem, Director @TCI_UW_Madison, Theoretical chemistry & Biophysics, Blue Sky: @xuhuihuangchem.bsky.social
Steve Quinn @Steve_Quinn_Lab
639 Followers 640 Following Single-Molecule Biophysicist @UniofYork 🔬| Senior Lecturer| Biophotonics, Alzheimer's Disease, Model Membranes, smFRET | 🦋 https://t.co/u71pvXcvRc.
Bo Wang @BoWang87
30K Followers 3K Following Prof @UofT | Building first Virtual Cell @Xaira_Thera | Chief AI Scientist @UHN | AI & Bio & Healthcare | Inventor of scGPT, MedSAM, BioReason | Opinions my own
Nicole Frankenberg-Di... @FKBmicro
777 Followers 468 Following Professor for Microbiology @rptu_kl_ld w/ interest in phycobiliproteins, phage AMGs, moving towards synthetic biology. Views are my own.
Eirini Kaiserli @eirini_kaiserli
1K Followers 359 Following Plant Photobiologist. Associate Professor at the University of Glasgow, UK. Interested in nuclear architecture and gene expression.
Tina DM #SinCienciaNO... @TinaDomnguez
1K Followers 990 Following Associate Professor at @Univcordoba. PI of Cyano-Light Group: Photosynthesis & photoprotection & cyanobacteria 🦠🌞 💜 (she/her)
GRS/GRC Photosensory ... @GrcGrs
118 Followers 59 Following The GRS on Photosensory Receptors and Signal Transduction will take place in 2026 in Ventura Beach Marriott, California, USA!
Photosensory GRC @photosensoryGRC
47 Followers 106 Following Official Twitter of the Photosensory Receptors and Signal Transduction GRC&GRS. Next meetings GRS March 3-4, GRC March 4-9.
Irina Bezsonova @IrinaBezsonova
2K Followers 412 Following 🇺🇦 Associate professor UCONN Health. NMR, structural biology, ubiquitination, sumoylation, DUBs, sciArt, T1D, Also on BlueSky
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5K Followers 1K Following Life sciences x technology x markets per aspera ad astra
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178 Followers 222 Following Computational structural biology. Postdoc at Flatiron Institute.
Mayank Vora @aiwithmayank
10K Followers 192 Following AI doesn’t have to be complicated - I’m here to show you how to actually use it and break down the latest trends in AI and Tech.
SeedLegals @seedlegals
6K Followers 4K Following Start, raise and grow faster with SeedLegals. #1 in the UK for funding rounds, EMI option schemes, SEIS/EIS, cap table and more.
Anthony Rose @anthonyrose
6K Followers 2K Following Founder & CEO SeedLegals, the largest closer of funding rounds in the UK. Now in the US. The man behind the BBC iPlayer.
Konstantin Klyukin @KlyukinK
28 Followers 67 Following Postdoctoral Researcher in Computational Materials
Gina El Nesr @ginaelnesr
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Adaptyv Bio @adaptyvbio
3K Followers 2 Following You design proteins - we run the lab. We build an automated lab that enables anyone to become a protein designer.
Katarina Elez @ElezKatarina
115 Followers 197 Following PhD student in Bioinformatics at @FU_Berlin | Drug discovery, ML and molecular simulations | 🧑💻
Stanislau Yatskevich @StanislauY
216 Followers 129 Following Post doc at Genentech, former PhD student at MRC-LMB
Pivot Bio @pivotbio
7K Followers 354 Following Pivot Bio is one of the world's leading innovative agtech companies, delivering farmers patented crop nutrition technologies.
Karsten Temme @karsten
1K Followers 408 Following Entrepreneur, engineer, husband, dad. Chief Innovation Officer and co-founder of @PivotBio.
Science of the Times @SCIENCEotTIMES
12 Followers 10 Following Popular science podcast discussing topical science stories Produced by Streaming Spires Podcasts Hosted by Oxford Profs Syma Khalid and Tim Coulson
Bohrium @Bohrium_AI4S
893 Followers 116 Following Bohrium- AI for Science with Global Scientists! Join our Discord: https://t.co/Q6quPHZIu7 Follow us: https://t.co/fnkK3q2Qxq
Arfur Rock @ArfurRock
40K Followers 5K Following anon GP at your favorite multi-stage VC // OS intel for the private markets
Reiichiro Nakano @reiinakano
7K Followers 991 Following i like building awesome things with awesome people 🇵🇭 🇯🇵
Michael Figurnov @mfigurnov
4K Followers 961 Following Senior Staff Research Scientist @ Google Deepmind
Jorge Bravo Abad @bravo_abad
11K Followers 9K Following AI for Science | Prof. of Physics @UAM_Madrid. Author of "IA y Física": https://t.co/Nxue94kfOG & "Ciencia 5.0": https://t.co/Y3rBUU7Xzg
Tony Kulesa @kulesatony
10K Followers 2K Following biotech startups @pillar_vc, ai for science @encode_pillarvc founding team @EdisonSci Prior: @petribio @MIT, @BroadInstitute
tbepler @tbepler1
645 Followers 152 Following Scientist and Group Leader of the Simons Machine Learning Center @SEMC_NYSBC. Co-founder and CEO of https://t.co/YcCw0bpHZo. Opinions are my own.
Algae Foundation @AlgaeFoundation
259 Followers 58 Following We see a future that embraces algae as an essential solution for a sustainable and healthy planet.
Eric Matzner @EricCO2Removal
1K Followers 1K Following Using plants to mine nickel, while removing carbon through enhanced rock weathering at @MetalplantCDR | Fmr. Founded Project Vesta, @Nootroo
MetalplantCDR @MetalplantCDR
31 Followers 12 Following
Simone Reber @SimoneReber
988 Followers 349 Following Scientist. Interested in complexity, organisational principles, quantitative biology, frogs & coffee. Tweets here are my own. @simonereber.bsky.social
Nathan C. Frey @nc_frey
5K Followers 2K Following on the Second Quest @AnthropicAI | previously CTO & Co-Founder @CoefficientBio (acq. by @AnthropicAI) | ex-@Genentech | @MIT @Penn
Weilong Chen @vollon3
108 Followers 1K Following PhD Student @TU_Muenchen Previous @TheDPTechnology | @chalmersuniv | @VolvoGroup | BSc. NUDT 18'
Kevin Wood @KevinWoodUM
1K Followers 3K Following Associate Prof at UMich. We study microbial dynamics w/ models and expts inspired by physics. Papa, husband, IPA drinker, NBA/Kentucky bball fan. he/him/his
American Physical Soc... @APSphysics
256K Followers 266 Following Fostering a vibrant, inclusive, and global community dedicated to science and society. Join us: https://t.co/Jvs055fiDM
Helen Yu @Hypat1aYu
644 Followers 1K Following currently visiting @stanford| Cadet @42SiliconValley | gamer | #Caltech PhD in #Chemistry| #Calbear | Deshaies lab |#nerdftw | proof #fangirl
Diana Cai @dianarycai
5K Followers 650 Following Machine learning & statistics researcher. Research fellow @FlatironCCM. Posts on probabilistic ML, Bayesian statistics, decision making, and AI/ML for science.
Mariusz Czarnocki-Cie... @MariuszCzC
278 Followers 321 Following structural biologist in the Nowotny lab at IIMCB Warsaw
Ziyang Zhang @bignerdzzy
1K Followers 366 FollowingTrends for United States
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