Kamran @onlykamran
usually tweeting about science or stocks. MSc. in Molecular Genetics from #UofT, Neuromuscular disorders 🧬 #biotech Toronto, Ontario Joined October 2010-
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Kamran retweeted
You would have to rip every single one of my fingernails out one by one before I admitted I spent $25k/yr on Doordash
I really find this stat hard to believe... just exported my #DoorDash data to confirm, and i spent $25K last year just on that... how is anyone living on $40K/yr ?
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@SaraNayeem Problem for some companies is that the best sites and clinicians will ask for appropriate compensation. Quit balking at the actual cost to run trials 😉
@aloktayi The MaRS Discovery District is a good place to check out bio startups and more advanced biotechs. Its home to BlueRock, Deep Genomics, Cyclica, CCRM and others.
@snicobio @titicreus The early papers swapped out the encased AAV to target different tissues/organ systems. Not sure if the approach changed in anyway since then but it’s possible.
@titicreus @snicobio my understanding is that despite the lipid shell, the AAVs keep their natural/targeted tropism.
@snicobio Innovation in manufacturing will be huge! Redosing will also be a challenge. Immune evasion for the capsid is one battle, immune evasion for the genetic payload delivered is another. Here’s one new approach: nature.com/articles/d4374…
@labratorytenant @NatHarooni yeah, IP stakes for individual donors is a non-starter for institutions, IMO.
@labratorytenant @NatHarooni I haven’t seen it at the individual level, takes a village for these deals to be made. Though some foundations have taken equity stakes. CF foundation made a couple Billion with Vertex. None goes back to donors but being less reliant on funding = more moonshots.
@labratorytenant @NatHarooni Nah this way you get to feel good even if it loses, even though half your “donation” paid institutional overhead instead since it’s now a for-profit venture 🤣
@AnthonyLepore7 @yaireinhorn Getting to the liver was never the issue with LNPs
@TeslaAndBitcoin @elonmusk MD Anderson already exists
@DRnotaDR @NatHarooni easily one of the toughest areas in bio for reproducibility
@j_power1 @VitusBBB Chip makers might prioritize Tesla because they know it'll sell through as well
@avidresearch I'd understand the low sentiment due to method (use of AAV) and stage of development/preclinical model (nude mice)
Kamran retweeted
Speechless. #WeTheNorth
Kamran retweeted
KAWHI DANCING RT FOR PROSPERITY FOR THE REST OF THE YEAR
@BettingBruiser @davidhyde2 @KirkTousaw @adam_greenblatt @MikePHager Lol, if you have to dress up in scrubs, have hair and beard nets, shoe covers, go through air showers to get into the grow facilities, banning phones is a no brainer and should have been implemented from the get-go.
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