Rhiana C Simon, PhD @mouse_braind
A.P. Giannini Postdoctoral fellow @ UCSF // Molecular profiling of the subcortical 🧠 San Francisco, CA Joined November 2017-
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A new study finds that both fear conditioning and antidepressant treatment stimulate new neuron growth in adult mouse brains, suggesting a possible adaptive response to stress-inducing experiences as well as elevated serotonin. scim.ag/4v59Hj7
Congratulations to Corey Harwell, PhD, on receiving a Neurobiology of Brain Disorders Award from the @McKnightFdn. His research explores how brain circuits develop and function, with implications for understanding neurodevelopmental disorders. #UCSFProud tiny.ucsf.edu/wu7qcH
Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🍽️ Very happy to share a major update in our work on the hippocampus and lateral septum in calibrating food consumption! 🍩 Major thanks to our lab/collaborators! ⭐️ cell.com/neuron/fulltex…
@muruganmalu @gstuber Thank you so much! So glad that it's officially wrapped up~
Thanks to @westonfleming for the ephys, @brandy_briones for the behavior help, @KenIshii1223 and Sam Golden for the lightsheet data, and everyone else who chipped in along the way. Finally, thanks to @gstuber for his guidance and support throughout this project!
Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇 cell.com/neuron/fulltex…
New paper on arousal in the brain! What controls the controller?
Want to compare social and nonsocial reward seeking behavior? On STAR Protocols, we provide instructions for the assembly of a 2 choice operant chamber with an easy to use GUI-based acquisition system. Low cost and fully automated @STARProtocols sciencedirect.com/science/articl…
I am thrilled to announce that I have been selected as an A.P. Giannini Postdoctoral Fellow! 🥳 Feeling fortunate to have received funding for my work on neurodevelopment of the lateral septum
Excited about our minisymposium at @SfNtweets ! Join us Wednesday afternoon to hear about the functional organization of lateral septum - from molecules to circuits and computations! Session details here: abstractsonline.com/pp8/#!/20433/s… #sfn2024
Excited to attend SfN and present our unpublished work about the lateral septum control of social interactions. Be brave and don’t miss this Wednesday afternoon symposium.
Chk out our newest collab paper co-led w/ @tpatriarchi, & others. We developed & characterized a nociceptin opioid peptide sensor. Congrats to Xuehan, @carriestineUW (student in my lab) who co-led effort. DM to try. @nimh @NIDAnews @NAPECenter Link: nature.com/articles/s4146…
Our new sensor for the neuropeptide #nociceptin is now out in @NatureComms Fantastic teamwork with the @mbruchas lab and many other super collabs! Very proud of our student Xuehan for her PhD work! Check it out: rdcu.be/dLO3m 😉
Incredibly thankful to have had an opportunity to work on this project. I learned so much from @SodenLab and had a great time picking apart the VTA! Check out this thread to learn more about input specific regulation of VTA cell types 👇
Our new sensor for the neuropeptide #nociceptin is now out in @NatureComms Fantastic teamwork with the @mbruchas lab and many other super collabs! Very proud of our student Xuehan for her PhD work! Check it out: rdcu.be/dLO3m 😉
Thrilled to show my recent work about the regulation of dorsolateral septum GLP-1R neurons on feeding behavior. In this work, we showed that dLS-GLP-1R neurons and the inhibitory pathway to LHA can regulate feeding behavior. biorxiv.org/content/10.110…
Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…
We sequenced ventral pallidum and found: - Neuronal heterogeneity (14 GABA subtypes, 2 glut, 1 chol) - Shared cell types with neighboring regions (accumbens, BNST, preoptic area) - Homology between mouse and rat - Transcriptional impact of high-fat diet biorxiv.org/content/10.110…
Please check our newest study on @biorxivpreprint - a tour de force led by the phenomenal @Chris_M_Reid, describing the diversity of neurons in the lateral septum in terms of transcriptomics, anatomical distribution, connectivity and electrophysiology: biorxiv.org/content/10.110…
Please apply to join my lab at Research Triangle Institute in North Carolina! We are seeking Ph.D. level scientists to join our team to work on mitochondrial mechanisms in substance use disorders. Apply here (or please RT/share): careers.rti.org/jobs/11456?lan…
We are currently hiring postdocs with experience in rodent models. Ephys and viral techniques a plus. Please DM me or email [email protected] if interested!
Pleased to share the first preprint from the Opendak Lab! We identified the infant lateral habenula as a site promoting developmental transitions in social behavior and a locus of dysfunction following early adversity. Congrats team!! biorxiv.org/content/10.110…
Excited to share that my graduate dissertation work is now finally live on bioarxiv! Take a look if you're interested in learning more about the lateral septum's role in opioid withdrawal: biorxiv.org/content/10.110…
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