PAPER ALERT Thread! "Dorsal Hippocampus to Nucleus Accumbens Projections to Drive Reinforcement Via Activation Of Accumbal Dynorphin Neurons" Excited to see my work with @MassalyNiko in @jomoronc Lab published in @NatureComms! rdcu.be/dxcni
Thank you to all authors without whom this work would not have been possible @kristineyoon @_loroco @Aljo2545 @SidneyBWilliams @yuwayway @superkash and @robgereau – and twitterless Rob Heuermann, Sulan Pathiranage, Tania Lintz, Azra Zec, & Ashley Park.
Using excitatory opsin we found that dHPC stimulation drives reinforcing behavior. Despite the well-defined role of dHPC in memory formation and maintenance, this behavior is independent of CS+ and self-stimulation seeking directly stopped when US+ was not paired with the CS+.
@khairunisa_ibk @kristineyoon @_loroco @Aljo2545 @SidneyBWilliams @yuwayway @robgereau congrats Nisa and team, this is great!