Online now!📲 Inhibition of #autophagy-related protein 7 enhances anti-tumor #immuneresponse and improves efficacy of #immunecheckpointblockade in microsatellite instability #colorectalcancer Full text👇 jeccr.biomedcentral.com/articles/10.11… #Cholesterol #Microsatelliteinstability

DYK that you can talk to @RoussosTorres about her preclinical #CancerResearch investigating approaches to improve responses to #immuneCheckpointBlockade in #BreastCancer? #AACR24

Online!📲 Blood-based biomarkers in patients with #nonsmallcelllungcancer treated with #immunecheckpointblockade Full text⤵️ jeccr.biomedcentral.com/articles/10.11… #Liquidbiopsy #Immunotherapy

Gut bacteria strains could be the key to predicting cancer treatment success 🧬🔬🎯 news-medical.net/news/20240306/… #GutMicrobiota #CancerTherapy #ImmuneCheckpointBlockade #PredictiveMedicine #NatureMedicine #RareCancers #PersonalizedTreatment #Microbiome @NatureMedicine

When describing the results, @DrTomMarron (a co-author of the study) said, “Strikingly, we found that IL-4 blockade enhanced #LungCancer response to #ImmuneCheckpointBlockade in mice and in six lung cancer patients with treatment-resistant disease.” genengnews.com/topics/cancer/…

Using preclinical models in a study funded by our division, @ilaria_elia, @HaigisLab, et al. found that supplementing 1-carbon metabolism with formate during #ImmuneCheckpointBlockade enhances antitumor immunity @CD_AACR bit.ly/42glZHI.

Dr. Andrew Gentles (@askyperson) @StanfordMed #NCICSBC is using a #SystemsBiology approach to identify mechanisms driving response to #ImmuneCheckpointBlockade in clear cell #OvarianCancer and clear cell renal cell carcinoma (#ccRCC). cancer.gov/about-nci/orga…

How does #melanoma resist #ImmuneCheckpointBlockade? Researchers at @vib_ccb explored the role of TCF4 and cells in a #mesenchymal-like state. @jchrismarine @pozniak_joanna @DennisPedri 📃 @CellCellPress: bit.ly/3Sbg1Et ▶️: bit.ly/3SlDqTU

Dr. Michael Karin @UCSanDiego is presenting highly penetrant and immunogenic mouse models of non-viral #HepatocellularCarcinoma that enable the evaluation of #ImmuneCheckpointBlockade. #Models4CancerResearch

Happy to share our thoughts on what the future holds for oncolytic virotherapy. More data forthcoming in conjunction with #immunecheckpointblockade @MarkTysonMD @cgoncology science.org/content/articl…

Using preclinical models in a study supported by our division, @escobar_giulia, @Luca_Biasco, @AnaAndersonlab, et al. found that TCF1 plays an important role in anti-tumor T cell mediated immunity and responses to #ImmuneCheckpointBlockade @Cancer_Cell bit.ly/49ifDKU.

Online!📲 CD28/PD1 co-expression: dual impact on CD8+ T cells in peripheral blood and tumor tissue, and its significance in NSCLC patients' survival and ICB response Look here👇 jeccr.biomedcentral.com/articles/10.11… #Nonsmallcelllungcancer #ImmuneCheckpointBlockade @IREISGufficiale

In a study funded by @YaleMed #NCICSBC, @MarcusBosenberg et al. showed that targeting myeloid cells in combination with #ImmuneCheckpointBlockade overcomes #immunotherapy resistance in preclinical models of #melanoma @CIR_AACR bit.ly/3ZT9Gjj.

Dr. Andrew Gentles (@askyperson) @StanfordMed #NCICSBC is using a #SystemsBiology approach to identify mechanisms driving response to #ImmuneCheckpointBlockade in clear cell #OvarianCancer and clear cell renal cell carcinoma (#ccRCC). cancer.gov/about-nci/orga…

.@MSKLibrary feature: Novel Genetic Subtypes of Urothelial Carcinoma w/Differential Outcomes on #ImmuneCheckpointBlockade @MichalSarfaty @MSK_DeptOfMed @MSKPathology @AMRegazzi @MSKBiostats @illumina @bengrbm @DrRosenbergMSK @GeneCollector @JCO_ASCO dx.doi.org/10.1200/JCO.22…

In his answer, @yarmo111 said that his lab’s peptide-centric CARs are directed at the tumors that don't respond to #immunotherapies like #ImmuneCheckpointBlockade or vaccines that rely on a high mutational burden. nature.com/articles/s4158… #CMSSJI

He is sharing his work on rationally combining BiTE - T cell therapy & #immunecheckpointblockade. #CMSSJI #CancerMoonshotSeminar

Dr. Nina Bhardwaj (@BhardwajLab) @MountSinaiNYC is investigating myeloid cell-mediated resistance to #immunecheckpointblockade in #bladdercancer. labs.icahn.mssm.edu/bhardwajlab/ #CIM23 #Immune2Cancer

How do bacteria affect #ImmuneCheckpointBlockade? 🦠 Researchers at @GustaveRoussy investigated if bacteria that rebound after antibiotics are administered affect cancer treatment responses. @ScienceMagazine paper: bit.ly/3PB3gCe Discussion: bit.ly/3CKoohP

Using experimental models in a study supported by our division, @AlCharestLab @BIDMChealth et al. revealed that driver mutations play a role in the immune landscape and response to #immunecheckpointblockade in #glioblastoma @CIR_AACR bit.ly/3N9ZtZS. #CIM23 #Immune2Cancer