Prof. Haryana Dhillon @hagsie
Psycho-oncology (living with cancer) researcher. Despite imminent collapse of civilisation & mass extinction, trying to help. Moving to: @hagsie.bsky.social Sydney, Australia Joined October 2010-
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@oncology_bg Thanks for making time to chat over breakfast @oncology_bg, especially after just getting back from a trip yourself! Looking forward lots of ongoing collaborations!
‘Shared Decision Making is about what makes sense for THIS patient; it is a method of care; it is NOT an extra thing to do. We need to create the conditions for care to occur in our health systems.’ Fantastic insights by Prof Victor Montori at @LHSCCanada
Consistency of physical activity is key in reducing incidence and mortality from digestive cancers. Optimal dose of consistent physical activity to reduce DCS risk and mortality at ~17 MET-hours/week more than doubles the recommended guidelines. jamanetwork.com/journals/jamao…
Register for the Lecture using this link: forms.office.com/pages/response…
I will join Prof Wendy Lam & Mr Glynn Chambers to talk about the certainty and uncertainty of living with a #cancer diagnosis #PsyOnc @POCOG1 @Sydney_Science #SuppOnc #SurvOnc #FCR #PsychoOncology #OzOnc linkedin.com/posts/psycho-o…
For me, one of the biggest surprises was how few oncologists use resource-stratified guidelines. Indian oncologists mainly seem to prefer the main NCCN/ASCO/ESMO guidelines and not the resource-stratified versions. bmjoncology.bmj.com/content/4/1/e0…
About 3-5% of us have a little raised line between the lower end of the vulva and the anus. This perfectly normal feature is called a raphe. It's pronounced "ray-fee", not like the name of the actor Mr Fiennes.
With all due respect, @MerriamWebster, I am far from optional—at least for those who favor civilization over confusion, chaos, and anarchy.
The Oxford comma (also known as the ‘serial comma’) is the comma that separates the second to last item in a list from a final item that is introduced by ‘and’ or ‘or.’ It is optional...but be aware that not using the serial comma can result in some ambiguity.
Really hot off the press. As hot as it can get. Right from the oven. 😊 bmjoncology.bmj.com/content/4/1/e0…
Just published in @BMJOncology #openaccess led by @HealthCommunic2 and with @SirohiBhawna and other colleagues in India. Results from a qualitative study of Indian oncologists on their perceptions regarding FDA approval and different guidelines. 🧵 bmjoncology.bmj.com/content/4/1/e0…
🏳️🌈 New Report: Advancing# LGBTQ+ Inclusion in #Cancer #ClinicalTrials provides insights into current data collection practices & addresses systemic issues faced by patients, clinicians, & researchers regarding sexuality and gender disclosure. @POCOG1 linkedin.com/posts/psycho-o…
Plasma. The golden gift that keeps on giving. Packed with powerful elements, plasma helps treat a wide range of serious conditions - from immune disorders to chronic illnesses, emergency care to protecting unborn babies. #lifebloodau
I'll have my take on the most important trials from #ESMO25 soon on my regular ESMO roundup video, so stay tuned. In the meantime, please consider these general points before you start claiming every trial with a P < 0.05 is the new standard of care. You don't need to think critically to claim that everything is practice-changing. 1. Prognostic biomarker is not the same as predictive biomarker. A good prognostic marker alone doesn't make a good surrogate. I'm talking path CR rates and ctDNA. They are good prognostic markers but not predictive or a surrogate. thelancet.com/journals/eclin… 2. Perioperative trials! We need to know the contribution of components. We are overtreating our patients. Having fatal AEs or life-altering AEs in a curative setting is not "acceptable" or "well tolerated". Even 1 additional cycle is too much if it's not adding any benefit. nature.com/articles/s4157… 3. Don't inflate benefit by quoting relative risk reduction when absolute risk reduction is dismal or baseline (control arm) risk is pretty low to begin with. 4. When we are running 1000s of trials of immunotherapies, of course, we will get many false positives (we wouldn't know which one). Slicing an individual trial data further into dozens of subgroups further intensifies this risk of seeing things where there is nothing to see. So don't make any clincal inference based on these subgroup analysis.
Saying this again louder for the #ESMO25 audience. If OS couldn’t be shown due to crossover, the correct interpretation is that the drug can be reserved at the next line without compromising outcomes.
@oncology_bg @oncodaily @TheLancetOncol @SamuelXStevens @lateuwen Thanks. So much good stuff in there but here is one of the most important: crossover. If crossover contaminates OS then it simply tells you there is no OS value in bringing the drug earlier or combining with earlier line treatment - you could and should just use it sequentially.
Read @POCOG1's post sharing a new study exploring #BrainTumour related personality and behaviour change in adults with #BTSM - it is not much talked about and carers and families are dealing with it as best they can. #SuppOnc #PsyOnc linkedin.com/posts/psycho-o…
@oncology_bg @oncodaily @TheLancetOncol @SamuelXStevens @lateuwen Trial design to get a dodgy drug registered: - no crossover - substandard control - no access to post study Rx - don’t look in mirror Want to improve OS, patient well-being, do the right thing? - allow crossover - best comparator - best post-study treatment - assess sequencing
@oncology_bg @oncodaily @TheLancetOncol @SamuelXStevens @lateuwen Thanks. So much good stuff in there but here is one of the most important: crossover. If crossover contaminates OS then it simply tells you there is no OS value in bringing the drug earlier or combining with earlier line treatment - you could and should just use it sequentially.
New The Lancet Oncology Paper on FDA Guidance for OS in Cancer Trials - Bishal Gyawali (@oncology_bg) @TheLancetOncol @SamuelXStevens @lateuwen oncodaily.com/voices/bishal-… #OncoDaily #Oncology #Cancer #Health #Medicine #MedTwitter #MedEd #MedOnc #MedNews #ESMO #ESMO25 #ESMO2025
🚨New paper🚨 We identified how #carers & #HCP define & describe #BTSM #BrainTumour related personality & behaviour changes. They are nuanced & complex. Grief, isolation & safety concerns are experienced by carers. #Aggression is a major concern. link.springer.com/10.1007/s00520…
Conference highlights from #anzup25 @ANZUPtrials in Sydney! @declangmurphy catches up with a bunch of delegates. Supported by our Conference Highlights Partner, Bayer China youtu.be/OgtKDhASzy0?si…
Louise Sharpe @LSharpeUSYD
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Australian Museum Eur... @eurekaprizes
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