Ginny Farias @ginny_farias
PI, Cell biologist loving neuronal morphology, organelle dynamics & inter-communication, polarized protein trafficking and more... cellbiology.science.uu.nl/research-group… Utrecht, Netherlands Joined May 2014-
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Excited to share our recent work ahead of publication. See👇
The main project of my PhD: "Spatiotemporal proteomics elucidates trafficking and localization of Neuroligins to the axon initial segment plasma membrane" is now on BioRxiv! Thanks to all collaborators🤝biorxiv.org/content/10.648…
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Paper from the lab 👇Team effort. The two first authors, Derk & Noortje, PhD students are now on the market for a postdoc position!
Our manuscript on the role of the calsyntenin adaptors in biosynthetic axonal transport is on BioRxiv now: biorxiv.org/content/10.648… It was a pleasure to work on this with my colleague and friend @DerkDraper . Special thanks to @JKlumperman and @ginny_farias for their support.
Ginny Farias retweeted
Our manuscript on the role of the calsyntenin adaptors in biosynthetic axonal transport is on BioRxiv now: biorxiv.org/content/10.648… It was a pleasure to work on this with my colleague and friend @DerkDraper . Special thanks to @JKlumperman and @ginny_farias for their support.
Ginny Farias retweeted
Secretome translation shaped by lysosomes and lunapark-marked ER junctions nature.com/articles/s4158…
Ginny Farias retweeted
Many thanks to Amelia Glazier and The Journal of Cell Science for including me in ‘First Persons’ through the decades – 100 years of notable scientists in The Journal of Cell Science journals.biologists.com/jcs/article/13… Happy to be in such great company!
Ginny Farias retweeted
Endoplasmic reticulum junctions serve as a platform for endosome-lysosome interactions through their stop-and-go motion switching | Science Advances science.org/doi/10.1126/sc…
Proud of my PhD student Ha Nguyen that presented a poster of her preprint and got 1st place :) Congrats, Ha!
New preprint from the lab. Amazing work from Ha Nguyen, PhD student in our lab. Thanks to collaborators! See thread 👇
Ginny Farias retweeted
This is going to be a very exciting meeting! Registration is now open. 🔬🌈🧫
Registration is now open to attend @J_Cell_Sci's meeting on Imaging Cell Dynamics, to be held in Spain in 2026 and organised by @Fran_Bottanelli, Guillaume Jacquemet, Giulia Zanetti & @DrMichaelWay. Find out more and apply to attend at biologists.com/meetings/jcsim… #JCSimaging
Ginny Farias retweeted
HOPS disruption impairs APP trafficking and processing, promoting exosomal secretion of APP-CTFs | bioRxiv biorxiv.org/content/10.110…
Check out our new preprint from the Farias & Klumperman labs about the role of HOPS in APP trafficking and processing. Thanks to collaborators! See 👇
I am happy to share our work on the role of the HOPS complex in APP trafficking and processing! 💫 Out now on bioRxiv: biorxiv.org/content/10.110…
New preprint from the lab. Amazing work from Ha Nguyen, PhD student in our lab. Thanks to collaborators! See thread 👇
Excited to share our preprint, now available online on BioRxiv! biorxiv.org/content/10.110…. We uncovered the coupling of translation and secretion machineries at the #axonalER to promote local delivery of axonal transmembrane proteins (TMPs) to the plasma membrane.
Ginny Farias retweeted
4Pi-SMS and pan-ExM reveal, in a close collaboration with the Rothman lab, a surprising tetraplex organization and self-assembly of rim golgins, which we believe can explain stack formation of the Golgi apparatus: biorxiv.org/content/10.110…
Ginny Farias retweeted
Target ALS is now accepting proposals for a new funding opportunity to accelerate the discovery of novel, biologically rational therapeutic targets for ALS. LOI due 6/17/25. Learn more and apply: bit.ly/4hTndPm #ALS #ALSResearch #FundingOpportunity
Ginny Farias retweeted
Really interesting plant work in @Dev_Cell examining ER sub-domains where peroxisomes and lipid droplets bud. cell.com/developmental-…
Ginny Farias retweeted
New study by Luján et al. from Vivek Malhotra's group @CRGenomica (rupress.org/jcb/article/22…) details the molecular mechanism of a rare illness that causes transient paralysis and dangerous arrhythmias. More in the news @elpaisinenglish: english.elpais.com/science-tech/2…
Happy to see our POTATOMap tool & story about biosynthetic LAMP trafficking published. Tool in addgene, proteomic raw data available. See 👇
nature.com/articles/s4146… POTATOMap is officially out today (even tho it says 2024-12-30)… long story 😂 Constructs are available on addgene and POTATOMap data is available on PRIDE repository. Thank you so much to everyone involved!!
Ginny Farias retweeted
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy biorxiv.org/content/10.110…
A nice story from @JKlumperman lab. Role of Vps41 in the recruitment of biosynthetic LAMP. Check out 👇
Sanzà, Klumperman et al. @UMCUtrecht reveal a novel role of VPS41 in cellular trafficking, showing that it recruits biosynthetic LAMP carriers in a process dependent on the small GTPase Arl8b. hubs.la/Q035q9D-0 #Organelles #Trafficking
Ginny Farias retweeted
Ataxin-2 polyglutamine expansions aberrantly sequester TDP-43 ribonucleoprotein condensates disrupting mRNA transport and local translation in neurons cell.com/developmental-…
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