CompCy Lab @ UNC @comp_cy

single-cell bioinformatics lab focusing on the immune system! PI: @natstann /in {@unccs,@compmedunc}. compcylab.squarespace.com UNC-Chapel Hill Joined February 2021

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CompCy Lab @ UNC @comp_cy

2 years ago

Congratulations to Sneha for presenting her poster at the celebration for undergraduate research yesterday!

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Exciting week! 🎉 Next Monday, Sneha will defend her honors thesis 'Deciphering the Microglia Transcriptome: Unraveling the Consequences of Early Life Stress and Aging'. Next Tuesday Haidong will defend his PhD 'Set-based modeling and applications in single-cell bioinformatics'.

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Maria Brbic @mariabrbic

2 years ago

Our 🪐SATURN method is now out in @naturemethods! SATURN paves the way for universal cell embeddings, enabling integration of datasets across different species 🐒🐁🧍🐟🐸 Using protein language models, we encode biological meaning of genes in scRNA-seq datasets.

Nature Methods @naturemethods

2 years ago

SATURN performs cross-species integration and analysis using both single-cell gene expression and protein representations generated by protein language models. @jure @YanayRosen @mariabrbic @yusufroohani nature.com/articles/s4159…

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CompCy Lab @ UNC @comp_cy

3 years ago

Congratulations to our two amazing rotons Luvna and Yu-Chen for great rotations and for getting the neuroimmune and microglia projects going in the lab! 🧠

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CompCy Lab @ UNC @comp_cy

3 years ago

@DhuviKarthikey1 @alecplot @JJMilnerLab Nice, thanks Dhuvi for the photo!

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CompCy Lab @ UNC @comp_cy

3 years ago

Congratulations @alecplot for winning a best poster award at data science day for work predicting CD8 T-cell fates with @JJMilnerLab :) Truthfully, this a picture from last week, but is the same poster. Great job Alec.

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Jolene Ranek @JoleneRanek

3 years ago

Super excited to introduce DELVE (github.com/jranek/delve), an unsupervised feature selection method for improving inference of developmental or disease trajectories from noisy single-cell data: biorxiv.org/content/10.110… 😊(1/8)

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CompCy Lab @ UNC @comp_cy

3 years ago

@TonyCulos It’s okay Tony. It’s more fun to be solving impactful problems 🤩

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CompCy Lab @ UNC @comp_cy

4 years ago

Cytocoarsening was accepted at #PSB23. Congratulations Chi-Jane and Emma. Importantly, we are going to Hawaii 🌊 :) biorxiv.org/content/10.110…

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Jolene Ranek @JoleneRanek

4 years ago

Have you ever wondered if you could leverage RNA velocity data to better resolve biological trajectories or disease phenotypes? Delighted to share that our benchmarking study is out today in @GenomeBiology! Biggest thank you to @natstann @purvislab 😊 genomebiology.biomedcentral.com/articles/10.11…

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Natalie Stanley @natstann

4 years ago

Very proud of @JoleneRanek as her task oriented benchmarking study for integrating RNA velocity and gene expression for trajectory inference and outcome prediction is out today in Genome Biology! genomebiology.biomedcentral.com/articles/10.11… . 🥳

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CompCy Lab @ UNC @comp_cy

4 years ago

.@haidyi1 and @JoleneRanek are in Chicago @acm_bcb to present their new papers! 🙂🎉 CytoEMD presented by @haidyi1 : dl.acm.org/doi/10.1145/35… Distribution-preserving sketching presented by @JoleneRanek : dl.acm.org/doi/10.1145/35…

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CompCy Lab @ UNC @comp_cy

4 years ago

Congratulations to Chi-Jane who led our new paper on graph coarsening approaches for single-cell data. We show that by shrinking the graph in a principled way, you can achieve similar performance in downstream bioinf tasks as if using the full graph. biorxiv.org/content/10.110…

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Natalie Stanley @natstann

4 years ago

Excited to share our new paper (to appear soon in ACM BCB!) about sketching single-cell data. 😀 Specifically, our sketches preserve cell population frequencies and of course rare populations ;), led by Vishal and @JoleneRanek arxiv.org/abs/2207.00584

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CompCy Lab @ UNC @comp_cy

4 years ago

Most recent lab photo a few weeks ago 😀 so lucky to work with the best students! 🥰

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Purvis Lab @purvislab

4 years ago

The influx of single-cell data is staggering—not just in volume but in its multiple modalities. How can we optimally combine these modalities to make biologically meaningful predictions? (1/7) biorxiv.org/content/10.110…

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CompCy Lab @ UNC @comp_cy

5 years ago

Happy to share our new work in collaboration with Junier Oliva and lead by Siyuan Shan on encoding and featurizing cellular landscapes with random Fourier features and kernel mean embeddings! ✨ arxiv.org/abs/2201.07322

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CompCy Lab @ UNC @comp_cy

5 years ago

Happy Holidays to all! Grateful for support from students, collaborators, colleagues and mentors in our first 11 months. :) Wishing you lots of CyTOF in 2022.