Cheyenne @booleanbio

Using ML and 'omics to power drug delivery solutions @ MilliporeSigma. Just here to bool sh*t ✨ ceziegler.com Joined September 2022

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Cheyenne @booleanbio

3 hours ago

@UrnovFyodor @carlzimmer Why so pessimistic? Shouldn’t families have the option to treat diseased embryos instead of discarding them?

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Cheyenne @booleanbio

4 hours ago

@TrevorCampbell_ Took me 5 minutes to explain this joke to my husband after he asked why I was laughing

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Trevor Campbell @TrevorCampbell_

a day ago

Bio red-teaming group called mCherry

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@DdelAlamo Hard to not be a pessimist about self-reported results, especially if the binding curves are not shown/reported. Even with open source work a lot of these affinities seem unreliable and we are seeing much different success rates for some networks than reported in their papers

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Cheyenne @booleanbio

2 weeks ago

@josiezayner To go niche is also viable, especially if you are integrating lab testing into the computational flow and pipelines. You can solve one very specific problem and do it well rather than try to build a “biological world model,” which requires much more compute and resources

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Cheyenne @booleanbio

3 weeks ago

@celinehalioua 100%. The world would literally need to end for me (or my future kids) to experience the same level of poverty. I guess the only question is how can we make sure our future progeny won’t feel acceleration induced FOMO and instead just focus on making a difference.

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Cheyenne @booleanbio

3 weeks ago

@parmita This is the right move. We’ll never learn to operate without mice if we never remove them from our processes.

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Cheyenne @booleanbio

3 weeks ago

@Jeffliu6068Liu @ycombinator @sklin_lite @LiYaoHuang2 Sent! We do custom formulations, AI-guided lipid design, and animal testing all in-house. Easy one stop shop for any startup with possibility to scale using our contract manufacturing org.

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Cheyenne @booleanbio

3 weeks ago

@CathyTie I think the parents living with these diseases are the most informed to make a decision about passing them down. Many families already ARE making these decisions, but we are limited to discarding precious embryos that still have potential to be a live birth.

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Cheyenne @booleanbio

a month ago

@TensorTwerker That’s gotta be one nasty keyboard. I’m imagining a Winnie the Pooh sort of situation

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Cheyenne @booleanbio

a month ago

@SimoneSyed My first instinct was to pick red, but then I realized if blue failed, I’d be stuck with all the other aholes that picked red and that sounded pretty terrible. Better to pick blue.

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Cheyenne @booleanbio

a month ago

@CathyTie Thank you Cathy for fighting for the people and patients this affects! Also a big thanks to the couple who spoke last night. To be in the thick of 3 years of IVF and stand in front of a bunch of people who happily deny you the care you desire, takes so much strength

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Cheyenne @booleanbio

2 months ago

@parmita Cell therapy will be one of the most effective anti aging treatments IMO

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Mgoes (bio/acc 🤖💉) @m_goes_distance

2 months ago

I interviewed @geochurch and learnt we're already gene editing humans. You just haven't noticed. 0:00 - Gene Editing Mammals → Humans 8:36 - Germline vs Somatic 14:56 - Modified Humans Are Already Here 18:50 - Enhancing Healthy Humans 25:00 - Aging Therapies vs Cognitive Enhancement 30:20 - Embryo Selection 38:10 - Is US Losing To UAE? 42:33 - Biotech Failures 49:31 - Next Dire Wolf Moment 54:21 - AI x Science 1:02:07 - Synthetizing Entire Genomes

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Cheyenne @booleanbio

2 months ago

@m_goes_distance Awesome episode. Watched it yesterday

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Cheyenne @booleanbio

2 months ago

@somewheresy Don’t leave once you succeed. Keep at it, keep winning.

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Cheyenne @booleanbio

2 months ago

We should give the average AI user the ability to run their own experiments, submit their own regulatory filings, etc, etc IMO this is an appeal to heaven scenario. People should be given agency over their own health and treatments, choosing how much risk they are willing to take on.