‼️New preprint‼️ 🔗Led by PhD student @SEMastenbroek, we unveil three different progression patterns of Lewy body pathology. Disease progression modeling of: * Postmortem Lewy-type α-synuclein data from 10 🧠 regions * N=814 donors 👇👇👇 biorxiv.org/content/10.110…
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1⃣ The aggregation of α-synuclein into Lewy bodies (LB) is a hallmark pathology of LB disease. Pioneering prior work has sought to define progression patterns of LB pathology based on postmortem data.