Beatriz Fernandez Fernandez @beaff26
Renal medicine, MD PhD, scientist-physician. Constantly moving forward, always learning .She/her. Joined February 2014-
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We are EuReCa-M: meet and join us at ERA Bodies booth inside the Members’ Networking Lounge (Hall 5 – Ground Level).Friday, June 5, from 9 to 10 BST , we are open for discussion, collaboration and science!
#ERA26 #OpenYourmind #AI in Healthcare How is artificial intelligence transforming hypertension and diabetes care? Let's hear 🪑🪑Espen Nordheim and Beatriz Fernández Fernández 1/9 🔰Machine learning tool: are the solution to accurate BP measurement and prediction of incident HT? 🗣️Claudia Torino 📍ABPM recommended but difficult in clinical practice Cuffless wearable devices 📍PPG 📍Newer tools integrated worn ML - less sensitive ti skin tone
¿Y si parte del beneficio cardiovascular de los GLP-1 ocurriera dentro de la placa? ➡️Reducen citoquinas (TNFα, IL-6, IL-1β) y moléculas de adhesión, suprimen el inflamasoma NLRP3 y favorecen el flujo de colesterol → placa más estable. Más allá de la glucosa y el peso 👇 🔗 frontiersin.org/journals/cardi…
3/ 📍More plant protein is linked to lower CKD risk, slower CKD progression, and lower mortality. 📍These benefits may reflect the overall plant-based dietary pattern, not plant protein alone. 📍Fiber improves metabolic and cardiovascular health and relieves constipation. 📍Fiber promotes a healthier gut microbiome, reducing uremic toxins and inflammation. 📍Small trials suggest fiber supplementation may lower uremic toxins and inflammatory markers #ERA26
2/ #ERA26 📍CKD potassium advice often overemphasizes fruits and vegetables while overlooking potassium additives and processed foods. 📍K burden depends on the food source, preparation, and overall dietary context. 📍Fiber, alkali, and glucose in plant foods may help buffer potassium rises. 📍Plant-rich diets provide benefits beyond potassium: fiber, alkali, healthier fats, antioxidants, and less absorbable phosphorus. 📍Focus on food quality and potassium source, not just potassium cont
Starting strong with controversies in nephroprotection #ERA26 @jjcarrero1 talking about potassium 🍌🥑 📍Plant-rich diets do not inherently cause protein deficiency in CKD. Plant phosphorus is less absorbable, so plant-based diets may ⬇️ phosphate burden despite similar phosphorus intake 📍The evidence supporting routine restriction of fruits and vegetables to prevent hyperkalemia is weaker than traditionally believed 📍Focus on food quality and individual risk, not automatic avoidance of plant foods.
⚠️AKI may be driven by a mtDNA–NETs vicious cycle. ⤵️ ALDH2 promotes SLC25A33-dependent mtDNA leakage, triggering ✅NET formation and ✅PANoptosis. 📌NETs then amplify ⤴️mtDNA release, perpetuating tubular injury⚡️ 📌ALDH2 activation (Alda-1) or NET inhibition (DNase-I) improved kidney injury in experimental models‼️ 💡Novel ALDH2–SLC25A33–mtDNA–NETs axis = potential therapeutic target in AKI. #ERA26 #AKI #KidneyResearch
Simultaneous publication during #ERA26 LBCT1 session have a look 👇👇👇
Presented today at #ERA2026 ⤵️ Atrasentan in patients with IgA nephropathy (ALIGN): final 2·5-year results from a randomised, double-blind, placebo-controlled, phase 3 trial 🔗 spkl.io/60117BZMB @ERAkidney
1/Biomarkers are emerging as a highly promising, non-invasive tool to accurately diagnose immune checkpoint inhibitor-related complications. 🎯#ERA26
4/ Enrollment #ERA26 ▪️1,458 randomized. ▪️Median follow-up: 1.7 years. ▪️Stopped early by DSMB. Baseline ▪️Age 63 years; 30% women. ▪️49% dialysis-dependent. ▪️78% had diabetes. ▪️Groups well balanced.
LBCT #ERA26 Nurandociguat phase 2 trial ALPINE 1 On RASi Titrate drug from 2.5 to 20 mg every two weeks Primary: Evaluate dose response of mean change in log UACR at 16 weeks Secondary: change in eGFR and UPCR for baseline to 16 wk
5/ eGFR slope #ERA26 👍Benefit extended to SGLT2i users despite small numbers (n=64) ⚖️Week 136 eGFR difference: +9.1 mL/min/1.73 m² vs placebo 📉Annual eGFR decline reduced by 83% in the SGLT2i stratum 👉Similar benefit in pooled analysis (+3.3 mL/min/1.73 m²; 41% slower decline)
Atrasentan in patients with IgA nephropathy (ALIGN): final 2·5-year results from a randomised, double-blind, placebo-controlled, phase 3 trial - The Lancet thelancet.com/journals/lance… #ERA26 @SENefrologia @SOMANEorg
Excited to see this being published
Chronic kidney disease (#CKD) affects 788–844 million adults worldwide — and is projected to become the fifth leading cause of death by 2040. A new Series, presented today at #ERA2026, examines what is needed to change this trajectory: spkl.io/6012765nY @ERAkidney
Los agonistas del receptor de GLP-1 no solo bajan glucosa y peso, cada vez hay más evidencia de un efecto antiinflamatorio directo en múltiples órganos. La inflamación crónica es el hilo que conecta diabetes, enfermedad cardiovascular, hígado y cerebro. Revisión de esta semana en JCEM 👇 🔗 pubmed.ncbi.nlm.nih.gov/42219869/
🫘Core curriculum de obesidad en Enfermedad Renal Crónica y su papel como el principal factor de riesgo (por prevalencia) para el desarrollo y la progresión de la ERC. doi.org/10.1053/j.ajkd…
NEW on the #AJKDBlog: @Maximal_Change interviews Jia Wei Teh and @MichelleOShaug3 about complement inhibition in Immunoglobulin A Nephropathy (IgAN): bit.ly/AJKDBlogTehINTV
Urinary rituximab loss and rate of treatment failure in membranous nephropathy
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長澤 将(Tasuku N... @RealTNagasawa
8K Followers 2K Following ###東北大学病院 腎臓内科 20年の臨床を、医学書24冊に凝縮 Antaa 178万閲覧・保存1万超(29本) 研修医と臨床判断を一緒に考える 🆕新刊『安い!早い!検尿のススメ腎臓診療に役立つ 尿』6/12発売(文光堂) https://t.co/8iXrEiqI0I
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Gabriela pierina Uzur... @uzuriaga_r6526
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Deimante @soyeimantecom
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Edgar V. Lerma 🇵�... @edgarvlermamd
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64K Followers 4K Following Saying the product of the kidneys is urine is like saying the product of a factory is pollution. Urine is a by-product. The product is homeostasis COI: link👇🏼
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90K Followers 305 Following #POCUS #MedEd education 📖 | by Abhilash Koratala MD @KoraAbhi, Nephrologist & Intensivist | @MCW_Nephrology I Founding Member @POCUSIAPN | X≠ medical advice
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15K Followers 163 Following Professor, Mayo Clinic, MN. 💯renal pathology. Use X to teach, clinical info changed=protect confidentiality. Be kind to animals. Love dogs. Views are mine.
CKJ @CKJsocial
16K Followers 4 Following Clinical Kidney Journal, an online open access journal of @ERAkidney published monthly by @OxfordJournals.
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3K Followers 783 Following Editorial board CardioRenal Medicine and Nefrología Journal
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35K Followers 670 Following Tweets from the eds of Nature Reviews Nephrology, a review journal covering the latest advances in the field.
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