Maximilian Euler @ayudo

If you assume everything will work out in your favor, bizarrely, it probably will.

There's so much power in believing things will work out, even when you don't know how or when.

Night Sky Today @NightSkyToday

2 weeks ago

🚨: Neuroscientists discovered something shocking: your brain doesn't care if your thoughts are true... it just believes whatever you think on repeat

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I'm convinced that 99% of success is just the ability to outlast uncertainty. The one who can tolerate the most uncertainty is the one who will eventually win.

I'm in love with this sentence: "No matter how talented you are, if you’re in the wrong environment, you won’t be valued."

🚨 @Karpathy predicted the power of the "LLM Wiki." Google just formalized it. Meet Open Knowledge Format (OKF): a vendor-neutral standard for giving foundation models the curated context they need. I can genuinely see this replacing Notion, Obsidian, or traditional wikis for developer teams, and the reason comes down to bookkeeping. Traditional wikis fail because humans inevitably abandon the tedious work of updating them. As Andrej Karpathy pointed out recently, LLMs don't get bored. They don't forget to update a cross-reference, and they can touch 15 files in a single pass. OKF standardizes the interoperability layer so agents can actually do that heavy lifting autonomously. Because the format is minimally opinionated, it doesn't dictate what you write, it just dictates how it's structured. You get: → Human-readable documents that live right alongside your code in version control → Cross-links that map out complex entity relationships without needing a graph database → A system that survives moving between different tools and organizations There is no complex compression scheme. No central registry. If you can cat a file, you can read it. If you can git clone a repo, you can deploy it. This is how we stop rebuilding context pipelines from scratch every time a new model drops. Announcement + spec file in 🧵↓

Claude Code creator: "100% of our pull requests at Anrtopic are run by Claude Code. 80–90% of code review too. The feature I’m using the most today is /loops. I’m not prompting Claude anymore - I’m building loops" in 1-hour interview, Boris reveals his setup, which helps him build the #1 coding tool of this year. Worth more than a $500 vibe-coding course.

Codez @0xCodez

a week ago

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This has quietly been a miracle month in medicine. In the last 5 weeks we’ve got news on: - retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels - RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life - small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol - Mayo’s AI-assisted radiology showing vastly improved cancer detection - this new therapy for metastatic solid tumors This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

Crémieux @cremieuxrecueil

3 weeks ago

This is actually insane. 97% of people taking the standard of care for metastatic solid tumor got worse by seven years. But with lorlatinib, that number was only 45% in the same time! This is an ENORMOUS jump in the quality of cancer care.

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This is a super exciting release - Claude Fable 5 is the same underlying model as Mythos but with added safeguards. The benchmarks are great and it's SOTA on everything by a margin but I'll add that *qualitatively* also, this is a major-version-bump-deserving step change forward (imo of the same order as Claude 4.5 was in November), peaking especially for long problem-solving sessions on very difficult problems. You can give it a lot more ambitious tasks than what you're used to, the model "gets it" and it will just go, and it's never felt this tempting to stop looking at the code at all (but don't do this in prod!). The model still has quirks that people will run into and the safeguards are configured to be a little too trigger happy for launch, which can hopefully be tuned over time. I feel a lot of things changing as working software increasingly comes out on a tap. The Jevon's paradox kicks in and I feel my own demand for software growing substantially. You can ask for anything - explainers, visualizers, dashboards, bespoke single-use apps (e.g. a full wandb that is hyper-specific just for your project), you can 10X your test suite, auto-optimize code, run giant research projects with custom HTML for the results, anything! "Free your mind" (Matrix ref). Really looking forward to all the things people build!

Claude @claudeai

a week ago

Fable 5 is state-of-the-art on nearly all tested benchmarks, with exceptional performance in software engineering, knowledge work, scientific research, and vision. The longer and more complex the task, the larger Fable 5’s lead over our other models.

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The hottest new programming language is English

🇺🇸 VICE PRESIDENT JD VANCE: “BITCOIN WILL BECOME A STRATEGICALLY IMPORTANT ASSET FOR THE UNITED STATES.”

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🚨 JUST IN: Cybersecurity leaders led by former Facebook CSO Alex Stamos urge the Trump administration to reverse restrictions on Anthropic's Mythos model, per Axios. They argue it hurts defenders more than attackers.

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Ace advice from Fable 5, just before it got banned 🥹

Elon Musk predicts that our current global economy will be comparable to cavemen throwing sticks into a fire given what the future holds and its current trajectory Right now, global GDP is fundamentally bottlenecked by the limits of human labor. We fight over finite resources and celebrate fractional productivity gains But the moment you scale real-world AI and humanoid robotics, that bottleneck disappears completely. So when the cost of physical labor approaches near zero, the old rules of economics will break indefinitely

A guy built a system of 7 Claude agents on his MacBook. No assistant. No sales team. No office. Every day it scans Google Maps across 3 cities, finds small businesses with no website or one from 2014, builds a landing page mockup, renders a 10-second video of it, and sends a personalized cold message — before he wakes up. 47 clients a month. $400 each. $18,800/month. $480 in API costs. Traditional web agencies run 8-person teams for the same order flow. He runs it alone from a MacBook and an iPhone. When a positive reply comes in while he's in a taxi, his Mobile agent books the Zoom call. He taps "approve" and joins 10 minutes later. The only time the system wakes him is when a deal breaks $3,000 or the reply rate drops below 12%. Everything else runs without him. Here's the complete playbook for building such $10K/month passive income machine with AI ↓

Khairallah AL-Awady @eng_khairallah1

5 days ago

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THIS MAN HASN'T OPENED HIS TASK MANAGER IN A WEEK AND HIS ENTIRE LIFE IS STILL ON TRACK he drops everything into one folder before bed and closes the laptop Claude opus runs at 8pm. by morning every note is sorted, every stalled project is flagged, every task is assigned Obsidian holds the vault. NotebooklLM reads across it. nothing requires a decision and nothing gets lost his coworkers are still living in their inboxes Fable 5 would have run this even better - it just got blocked by the US government. Opus 4.8 is what's running now the stack: 📁 Claude ↳ claude.ai 📁 Obsidian ↳ obsidian.md 📁 NotebooklLM ↳ notebooklm.google.com

Mr. Buzzoni @polydao

2 months ago

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Elon Musk predicts that AI will bypass coding entirely by the end of 2026 - just creates the binary directly AI can create a much more efficient binary than can be done by any compiler So just say, "Create optimized binary for this particular outcome," and you actually bypass even traditional coding Current: Code → Compiler → Binary → Execute Future: Prompt → AI-generated Binary → Execute Grok Code is going to be state-of-the-art in 2–3 months Software development is about to fundamentally change

Watching people go back to Opus 4.8 because Fable and Mythos 5 are restricted.

Anthropic @AnthropicAI

6 days ago

The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees. The net effect of

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Social skills are becoming more important for job outcomes and pay. As AI handles more tasks, roles that rely on human interaction are seeing better returns. The economy is increasingly rewarding people with broad abilities—those who work well in teams, solve problems, communicate clearly, and think creatively. Chart from FT ft .com/content/5e2593a3-e834-4822-bbc8-7cb27086af24

@claudeai Don’t forget World of Claudecraft!! First Fable MMORPG: 6000 users in 10 hours

ZYZZ JOBS @maxpolaczuk

6 days ago

@claudeai Fable 5 just oneshot the first open-source MMORPG 🤯 Play it on worldofclaudecraft.com Contribute via github: github.com/levy-street/wo…

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