Alain Laederach @alaederach
RNA Folding Bioinformatics, Science, and a bright sunny day in the alps. ribosnitch.bio.unc.edu Chapel Hill, NC Joined April 2008-
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Data on Researchers’ Self-Reported Disability Status nexus.od.nih.gov/all/2022/12/13… Interesting read, I am glad to see @NIH highlighting this data!
RNA G-quadruplex rocks!Our exciting story is finally out! Novel insights on how plants adopt RG4 in response to cold. nature.com/articles/s4146… @JohnInnesCentre @ERC_Research @BBSRC @GEN_ISP_JIC @HaopengYu @XiaofeiYang14 @Ilexpurpurea @sduncan015 @kitkwok6
DNA uses thymine (T); RNA uses uracil (U) instead. Why?? Somehow I only recently learned the reasons and it’s quite neat. And as is typical in biology there are still open questions about it 🧵
@CorleyTwin2 I vote for 3 but I maybe a little biased in my opinion!
I enjoyed Wah Chiu’s talk here at #ncrna2022, his work in collaboration @RDasLab on L-21 group I intron structure brought back excellent memories of misfolding RNAs!
Excited to be at the #ncrna2022 meeting in person again, biggest turnout since this meeting started 25 years ago!
@ewang2323 @bio_eclipse Nevermind, I managed to find the original thread and find the link to your very nice Cellstemcell paper! And you did your due diligence and submitted to GEO at ncbi.nlm.nih.gov/geo/query/acc.…. One question, do you remember which GRC38 version you used?
@ewang2323 @bio_eclipse Hey @ewang2323 did you ever publish this work and is the an accession number for the ZFP36L2 eCLIP data in SRA/GEO?
Registration in open for the NC RNA 2022 tool and target meeting, with a great lineup of speakers. Please do consider registering at ncrna.web.unc.edu!!
RNA structure landscape of S. cerevisiae introns biorxiv.org/content/10.110… Very nice preprint by @RDasLab and @RiboHipster on pre-mRNA structure, glad to see we aren't the only ones thinking structure has got to be doing something in those introns!
Excited to attend @NC_RNA_Meeting October 13-14 in the triangle this fall. Check out ncrna.web.unc.edu for updates!
@peiferlabunc @alaederach Why that’s Microtubule Associated Protein Tau Expressed in brain, complex splicing gtexportal.org/home/gene/MAPT
Clearly the best way to get everyone in your lab to laugh is to make a joke at the expense of the PI! #science #RNA I think we are going to use this one on ribosnitch.bio.unc.edu
@mikelove @peiferlabunc Thanks Michael for clarifying my acronyms!
Our latest work on mRNA structure and splicing where Jaya Kumar in my lab predicted the footprint of the spliceosome on pre-mRNAs and used this in conjunction with endogenous structure probing to predict PSI in MAPT. elifesciences.org/articles/73888
@peiferlabunc @alaederach PSI = percent spliced in, a metric for how often a particular exon is included in the transcripts, for a given sample
@ChenRNAChen Yes, that is what the model predicts!
@FoxLabDuke @Sallen822 @UNC_Biology Very excited to have Scott come to UNC!!!
Scott Allen @Sallen822 is now Dr Scott Allen! Fantastic thesis defense today. Up next for Scott is a postdoc @UNC_Biology with @alaederach and Kevin Weeks.
Jeffrey Kieft @JeffreyKieft
3K Followers 636 Following Executive Director, NYSBC (@NYSBC_Science); RNA biochemist, biophysicist, structural biologist, and virologist. Go Army, Beat Navy! pronouns: he/him/his
Ronald Breaker @RonBreaker
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Yiliang Ding @YiliangDing
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Lior Pachter @lpachter
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Matt Disney @disney_lab
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Junjie Guo 郭俊傑 @guo_lab
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Nils Walter Lab @NilsWalterLab
2K Followers 214 Following We study cool RNAs - reaching unprecedented single molecule sensitivity with fancy microscopes and answering the question of how cellular life works
Igor Ulitsky @IgorUlitsky
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Das Lab @RDasLab
3K Followers 103 Following Our lab seeks an agile and predictive understanding of how RNAs structurally code for information processing and replication in living systems.
Silvi Rouskin @silvirouskin
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Elise White 🏳️�... @elisew00
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Bilingual Publishing ... @bilingual_pub
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The RNA Society @RNASociety
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Ronald Breaker @RonBreaker
4K Followers 109 Following Prof. Breaker is an RNA biochemist, Sterling Professor, and Chair of Molecular Biophysics and Biochemistry at Yale University, New Haven, CT.
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73K Followers 13K Following I science & try to make science open. Tweets do not represent my employer's views, but are always correct. My conflicts of interest https://t.co/77P0LDe6VR.
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671 Followers 78 Following I read that before the words 'download' and 'pdf' were invented.
Rebecca Robbins @RebeccaDRobbins
22K Followers 10K Following @nytimes reporter covering medicines [email protected] 714-478-4224 for calls, texts, Signal or WhatsApp
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