Happy to share our findings from the GENISOS cohort, exploring associations between gastrointestinal and cardiac involvement in systemic sclerosis. We look forward to future studies investigating the mechanisms underlying this interaction.
#Scleroderma#Rheum#GI#Heart
New insights into the gut–heart axis in early systemic sclerosis: distinct GI patterns were associated with specific cardiac phenotypes. Findings represent a step toward an integrated, multiorgan approach in SSc
Arthritis Care & Research
doi.org/10.1002/acr.80…
Kaplan-Meier
🧪Anti-cytolethal distending toxin (CDT) antibodies were found in 18% of SSc patients and strongly associated with RNPC3, U1RNP & Scl-70. Linked to worse GI symptoms, they may mark post-infectious autoimmunity.
@RheumJnlacademic.oup.com/rheumatology/a…
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