ChenLabToledo @Turfee
Cell biologist and Associate Professor @utoledo studies the role of actin cytoskeleton and calcium signaling during cytokinesis. Alumnus of @UTAustin @PKU1898 chenqianfj.wixsite.com/chenlabtoledo Ohio, USA Joined February 2009-
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ChenLabToledo retweeted
🔬 Cell-type-specific GCaMP6 miniscope imaging of a freely-behaving mouse brain. ~1,200 excitatory CA1 hippocampal neurons were imaged during active behavior over months. Courtesy of the Schnitzer Lab, Stanford. #MicroscopyMonday #Neuroscience #Lifescience
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@foodskop @UWMadison @uwgenetics @UW_LSC @UWMadisonarts Congratulations!
ChenLabToledo retweeted
In the latest issue! Calcium signaling in plants: Universal and unique paradigms dlvr.it/TR7bm8
ChenLabToledo retweeted
Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells @STARProtocols #bps2026 hubs.ly/Q04482qB0
ChenLabToledo retweeted
Step-by-step protocol and reproducibility Generate iPSC-derived 3D neurospheres for neuron–glia studies. Date: March 25 | Time: 12:00 pm ET Free Register: ascb.org/ascb-meetings/…
ChenLabToledo retweeted
Cell Bio 2026 is built by scientists, for scientists—and it starts with your ideas. Submit a scientific session proposal and help shape the program. 🗓 Deadline: February 22, 2026 Submit Now: ascb.org/cellbio2026/
ChenLabToledo retweeted
.@richa_rikhy lab @IISERPune show Drosophila Missing-in-Metastasis (DMIM) (also called MTSS1) promotes Rac1 mediated branched actin network formation & endocytosis to drive rapid, cyclical plasma membrane remodeling during embryonic syncytial divisions hubs.la/Q040wrqn0
ChenLabToledo retweeted
AlphaGenome is out in @Nature today along with model weights! 🧬 📄 Paper: nature.com/articles/s4158… 💻 Weights: github.com/google-deepmin… Getting here wasn’t a straight path. We sat down @GoogleDeepMind to discuss the story behind the model, paper & API: youtu.be/V8lhUqKqzUc
ChenLabToledo retweeted
Cell biology for a sustainable future – a call to action from Camila Costa, Eliott Flaum, Delfina Hlashwayo @DHlashwayo, Marie Jacobovitz, Guillermina Kubaczka, Samuel Lovat, Eliya Milshtein, Hanna Szafranska @HannaSzafransk1 and Soraya Zwahlen. journals.biologists.com/jcs/article/13…
ChenLabToledo retweeted
Review: Siqi Deng, Zhiqiang Yan et al. @hkust summarize the physiological functions and structural basis of OSCA/TMEM63 proteins, positioning them within a mechanosensitive ion channel superfamily. hubs.la/Q03ZL0yH0 #Physiology #Neuroscience #Mechanobiology #IonChannels
ChenLabToledo retweeted
New research from Lee, Higgs et al. @GeiselMed shows how #INF2, a key #actin regulator, is activated by calcium-calmodulin and free actin monomers. Actin-binding proteins like profilin and thymosin aren't just helpers - they directly tune INF2 activity. hubs.la/Q03ZT5_k0
ChenLabToledo retweeted
This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. elifesciences.org/reviewed-prepr…
ChenLabToledo retweeted
@NIH has launched the nation’s first dedicated Organoid Development Center to accelerate human-based research and to complement animal models. The center will support new 3D tissue models to study disease, drug response, and human biology. bit.ly/4pBYT9T
ChenLabToledo retweeted
Spotlight: Ivan Radin discusses new work from Ryken et al. (hubs.la/Q03YtQV90) which shows how localization and function of autoinhibitory calcium ATPases maintains the strength of the tip-focus Ca2²⁺ gradient during polarized plant growth. hubs.la/Q03YtTq30
ChenLabToledo retweeted
This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. elifesciences.org/reviewed-prepr…
ChenLabToledo retweeted
From MBoC... Tired of hand-annotating cell images? Ajit Joglekar and colleagues introduce Cell-APP, a tool that automates creating training data for cell-segmentation models—speeding up workflows and helping labs build models that fit their needs. 🔗 molbiolcell.org/doi/10.1091/mb…
ChenLabToledo retweeted
Leanna Owen, Margot Riggi, David Drubin, Janet Iwasa and Yidi Sun use molecular animation to depict the full progression of CME in budding yeast, with an accompanying Cell Science at a Glance article and poster. journals.biologists.com/jcs/article/13…
ChenLabToledo retweeted
KJ Muldoon, at less than a year old, was the first known person to receive a personalised CRISPR-based genome-editing therapy He is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/48Jm1M4
ChenLabToledo retweeted
Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction nature.com/articles/s4155…
ChenLabToledo retweeted
.@ElMossadeq, Dumont et al. show that an interkinetic envelope surrounds chromosomes between #meiosis I and II in #Celegans oocytes. hubs.la/Q03V-Xb20 📕 From The Year In Cell Biology: hubs.la/Q03V-VvW0 #CellBio2025
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