Michael J. Lee @TheLeeLab
A Laboratory of Systems Pharmacology umassmed.edu/lee-lab/ UMass Med School Joined September 2013-
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Our MEDUSA paper was published today in @nchembio! This is an approach for identifying death-regulatory genes, which we used to clarify different ways cells die following DNA damage. Congrats to @meganhoneywell @UMassChanGSBS and to the other authors! rdcu.be/dA4uj
Registration is open for the @FASEBorg meeting on Cell Signaling in Cancer, which will be held in Tucson, AZ June 16-20. Should be an awesome meeting at an exciting venue. Come join us!
Undergraduates looking for a summer research experience, you still have time to apply for the @UMassChan Summer Research Program in Quantitative Biology.
2nd Annual UMass Skiing and Science retreat!! “Ski it if you Chan!” @PitarresiLab @game_of_chroms @Marcus_Ruscetti @TheLeeLab
Seeking scientist volunteers! Want to practice science communication and help author a ✨comic✨ about your research? I need collaborators for this spring's cohort of SciComm & Comics art students! Please share widely. #STEMeducation #Science #sciart
Scott Dixon (@SJD956 ) and I wrote a short guide summarizing issues that affect evaluation of cell death💀Should be of interest to anyone that is exploring mechanisms of drug action, drug resistance, or those aiming to get deeper insights about death regulation. Please read!
Scott Dixon (@SJD956 ) and I wrote a short guide summarizing issues that affect evaluation of cell death💀Should be of interest to anyone that is exploring mechanisms of drug action, drug resistance, or those aiming to get deeper insights about death regulation. Please read!
New paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times. In @NatureCancer at rdcu.be/drhs0 by @HaeunHwangbo @SC_Patterson @PlanaDeborah 1/6
Congrats 🎈 🎉 Nicholas Harper on receiving a prestigious Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship from @theNCI. Harper is researching into cell death and #CancerTherapy at @UMassChan's @TheLeeLab. bit.ly/3P97KhB
Congrats again to Nick Harper on his F31 award through the NCI! umassmed.edu/news/news-arch…
➡️Join us at the next BCDI meeting on Monday Sept 11th at 3PM on the Harvard Med Quad (Goldenson 122) for exciting discussions led by @TheLeeLab on cell death in response to transcription blockade and @OylerYanivLab on cell death in infections. More info: BostonCellDeath.org
Junior investigators (grad students, postdocs, & early faculty) can register to attend #NCIJI2023. This meeting of #BDSTEP, #CCBIR, #NCICSBC, #NCIIMAT, #NCIITCR, #NCIMetNet, #NCIPDMC, #PSON, #NCISynBio & #CancerTEC will be Aug. 17-18. events.cancer.gov/dcb/ji-meeting…
What's the biggest mistake that I see pre-tenure assistant professors making? It looks like this: #AcademicTwitter #TenureTrack #AssistantProfessor #OnTrackforTenure
Excited to share our new preprint on estimating the rates of 3' end pre-mRNA cleavage, the result of a long labor of love by @LeslieTorresU (and contributions from @Ezecalvo)! (1/6) biorxiv.org/content/10.110…
Our preprint on how p53 controls the mechanism of DNA damage-induced cell death is out! Many thanks to the wonderful people in the Lee, Spinelli, Guertin, and Sarosiek labs for helping to make this paper everything I envisioned (and more) 🙂🧬
Our preprint on how p53 controls the mechanism of DNA damage-induced cell death is out! Many thanks to the wonderful people in the Lee, Spinelli, Guertin, and Sarosiek labs for helping to make this paper everything I envisioned (and more) 🙂🧬
Arjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12Juan Fuxman Bass @fuxmanlab
1K Followers 796 Following Scientist. Associate Professor at Boston University. Systems Biology, gene regulation, immunology, cancer. He/him 🏳️🌈UMass Chan Medical Sc.. @UMassChan
14K Followers 4K Following Official X home of UMass Chan Medical School: pioneering education, research and health care delivery. See how we are advancing medicine together.Joe Magrino @joemagrino0528
270 Followers 245 Following UMASS MED graduate student. Traveling to a city near you. #sciencetwitter 🏳️🌈 (he/him).Kate Fitzgerald @FitzgeraldKate
5K Followers 1K Following Innate Immunologist and Cytokine biologist 🇮🇪 UMass Chan Medical School. Opinions are my own.PitarresiPhD @PitarresiLab
1K Followers 2K Following Jason R. Pitarresi. Father. Assistant Professor @UMassChan Med School studying pancreatic cancer, cellular plasticity/metastasis, and tumor-host interactions.Michael Francis Lab @FrancisLab4
610 Followers 740 Following Our laboratory investigates molecular pathways that sculpt the connectivity of circuits, alter their performance, and shape behavior. @UmassMedicalRichard Sever @cshperspectives
21K Followers 1K Following Assistant Director of Cold Spring Harbor Laboratory Press, bioRxiv & medRxiv Co-FounderEric H. Baehrecke @BaehreckeLab
798 Followers 319 FollowingMichael Baym @baym
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2K Followers 833 Following Professor studying DNA replication and role in cancer, chemoresistance, and developmental diseasesMadeleine Oudin @MadeleineOudin
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3K Followers 457 Following Physician-scientist @DanaFarber @harvardmed. President, Society for Functional Precision Medicine @theSFPM. You probably should be BH3 profiling.Mary Munson @mary_munson4
4K Followers 5K Following Multidisciplinary research at UMass Chan focused on membrane trafficking. Opinions are mine (she/her)Elizabeth McKenna @ElizSMcKenna
16K Followers 5K Following Executive Editor of Cancer Discovery @CD_AACR, published by @AACR. @BBS_Harvard/@DanaFarber alum. Native New Yorker. Views/likes/RTs are my own. She/herHeidi Hehnly-Chang @LovelessRadio
2K Followers 2K Following Mom, Associate Professor at Syracuse University, Cell Biologist, music appreciator, novel reader, amateur equestrian, and budding artist.maureen hester @voM0cytosis
1K Followers 3K Following I like my dogs & not finishing knitting projects. I study immunology and fungi~ UMass Med Infectious Disease. Doin my absolute best to make #myCOOLogy happen.Clement Chow @ClementYChow
17K Followers 5K Following henfluencer - geriatric millennial - #stopasianhate - don’t call me Clem - emotional eater™️- he/him- @chowlabPrachee Avasthi @PracheeAC
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10 Followers 335 Following Gathеrеd on thе sitе of girls from all US statеs 😜 Thеy arе rеady to mееt Somе havе nakеd profilе photos! Watching this https://t.co/SdZlsTQNAhFrontiers - Bioinform.. @FrontBioinf
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355 Followers 321 Following Assistant Professor @Metabolcenter. Faculty Adjunct Assistant Professor @ProgMolMed.Sharron Whelchel @WhelcSharr
36 Followers 5K FollowingSidrah Zavala @ZavaSidr
31 Followers 5K FollowingMaxim Tsenkov @mitsenkov
368 Followers 790 Following Structural bioinformatician working at AlphaFold DB in the PDBe. Enriching protein structure models and implementing new tools.Perii Kızı🦋 @Perii88
341 Followers 360 FollowingAllyson Evans @metabolism_ally
233 Followers 86 Following Scientist, Editor-in-Chief, @Cell_Metabolism, metabolism, aging, mitochondria (views are my own)E_mma @Emma55733485981
3 Followers 352 FollowingSammy Tse @tse_elegans
128 Followers 213 Following Graduate student at UMass Chan studying intestinal innate immunity in C. elegans.Hotesheas @hotesheas5622
172 Followers 1K Following I'm new to Twitter accounts so I tried the messaging feature and it's great to meet you.Satoa @Satoa117957
7 Followers 370 Followingk @kknmkm
208 Followers 410 FollowingMorgan Phillips @morgan_neuro
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8 Followers 151 Following Postdoctoral Fellow @TheCrick @LabVousden, UK Former PhD Candidate @dukenus, Singapore Cancer metabolism & Signaling transduction 🇰🇷🇸🇬🇬🇧W Yenjai @Proteoentist
35 Followers 995 Following Student at @MahidolU working on target deconvolution. #CellDeath #Ferroptosis Views are my own.Kamyar Hadian @HadianKamyar
563 Followers 1K Following Research Group Leader @HelmholtzMunich | #Ferroptosis #Ubiquitin #CellSignaling #CellDeath #ChemicalBiology #DrugDiscovery | Proud Dad, Husband to @M_VincendeauTriona Ní Chonghaile @NiTriona
1K Followers 874 Following Cancer Biologist that likes killing cells - cancer cells. A Senior Lecturer at the Royal College of Surgeons in Ireland. Comments are my own.Collin Heer, Ph.D. @HeerCollin
375 Followers 2K Following K00 Fellow in @ranjitbindra lab @Yale. Studying electron movement in biological systems w/ focus on tumor cell NAD metabolism.Isaac Harris @isaac_s_harris
3K Followers 3K Following Assistant Professor @UR_med @Wilmot_Cancer. The Harris Lab works to understand the roles of #antioxidants in disease. Views are my own.Abolfazl Arab @abe_bio
254 Followers 869 Following Incoming PhD candidate @UCSF • Now: @arcinstitute • Past: @UCSF @HarvardDBMI • B.S. M.S. @UnivOfTehranSimone Alvarez @SimoneAlva49328
92 Followers 3K FollowingMai Ceesay (she/her) @MaiCeesayx
249 Followers 1K Following 🇸🇳 🇬🇲 PhD student @UmassChan - Views are 💯 mine إني معي ربي سيهدين 🙏Tigist Tamir @TigistTamir
652 Followers 955 Following Postdoc @kochinstitute @MITBPG|| Metabolism & cell signaling: I'm about omics,☕, 💃🏾, & TT|| PhD: @UNCBBSP @UNCIMSD|| @Edges_and_Nodes| 🤳🏾My opinionsSarah @sarah58pedigo
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5 Followers 117 Following Don't want to overdo it. It's good to be modest and reserved.Özen Leylek @leylek_ozenn
16 Followers 346 Following Postdoctoral Researcher | Barts Cancer InstitutePatrick Bhola @bholapat
92 Followers 192 FollowingSungJin Park @Sungjin2619
15 Followers 50 Following Postdoc, Greer lab, U of Mass Chan Medical School olfaction, neural wiring, behaviors, and cancerIan Cannell @IanGCannell
3 Followers 24 FollowingFrontiers in Systems .. @FrontSystemsBio
478 Followers 329 Following We've moved! Please follow our new account @FrontBioinf for updates on Frontiers in Systems Biology.Eleanor Sheekey @EleanorSheekey
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140K Followers 1K Following Don't be fooled by the rocks that I got, I'm still Oded from the block. TED: https://t.co/rcOm9TSTf5 Huberman Lab Podcast: https://t.co/xZTNlx9nbiArjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1Anne Carpenter, PhD @DrAnneCarpenter
22K Followers 2K Following Discovery in images. Enthralled by science. 5 kids. She. SAB Recursion, Quiver. Founder SyzOnc. https://t.co/CQCHnSAc9MHarmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/himJuan Fuxman Bass @fuxmanlab
1K Followers 796 Following Scientist. Associate Professor at Boston University. Systems Biology, gene regulation, immunology, cancer. He/him 🏳️🌈UMass Chan Medical Sc.. @UMassChan
14K Followers 4K Following Official X home of UMass Chan Medical School: pioneering education, research and health care delivery. See how we are advancing medicine together.NCI Systems Biology @NCIsysbio
4K Followers 43 Following @NCICancerBio Programs, including #NCICSBC & #NCIMetNet, using systems approaches to advance #CancerResearch. Privacy Policy: https://t.co/gKgYC5QgNuJoe Magrino @joemagrino0528
270 Followers 245 Following UMASS MED graduate student. Traveling to a city near you. #sciencetwitter 🏳️🌈 (he/him).Kate Fitzgerald @FitzgeraldKate
5K Followers 1K Following Innate Immunologist and Cytokine biologist 🇮🇪 UMass Chan Medical School. Opinions are my own.PitarresiPhD @PitarresiLab
1K Followers 2K Following Jason R. Pitarresi. Father. Assistant Professor @UMassChan Med School studying pancreatic cancer, cellular plasticity/metastasis, and tumor-host interactions.Michael Francis Lab @FrancisLab4
610 Followers 740 Following Our laboratory investigates molecular pathways that sculpt the connectivity of circuits, alter their performance, and shape behavior. @UmassMedicalDrug Monkey @drugmonkeyblog
9K Followers 240 FollowingRichard Sever @cshperspectives
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44K Followers 2K Following Bren Professor of Computational Biology @caltech. Blog at https://t.co/FFQzhEsmhi. Tweets represent my views, not my employer's. #methodsmatterItai Yanai 💔 @ItaiYanai
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10K Followers 212 Following The Man Behind the Maps: Legendary Ski Artist James NiehuesFrontiers - Bioinform.. @FrontBioinf
1K Followers 540 Following Research and updates from all @FrontiersIn journals in the field of bioinformatics and systems biology. #openaccessSki NH @SkiNewHampshire
10K Followers 332 Following 30 ski resorts, one stop. https://t.co/OkNc0Z0vl8Nezar Abdennur @nv1ctus
571 Followers 425 Following computational biologist / biological computer / asst prof @UMassChan / phd @MIT / https://t.co/Sv8B6sBfokMarie Sophie Lykke Is.. @Marie_Isidor
355 Followers 321 Following Assistant Professor @Metabolcenter. Faculty Adjunct Assistant Professor @ProgMolMed.Sugarbush, Vermont @Sugarbush_VT
22K Followers 2K Following Best Ski Town in the East – Outside Magazine; USA Today - Best Ski Resort, #1 in the East, and #2 in North AmericaFASEB @FASEBorg
11K Followers 885 Following FASEB — advancing health and well-being in the life sciences through collaborative advocacy. We are the voice of biological/biomedical researchers.Smugglers' Notch @Smugglers_Notch
15K Followers 1K Following America's Family Resort, a year-round vacation destination in Vermont's beautiful Green Mountains. The best vacation value for family fun! #smuggsloveSugarloaf Mountain @SugarloafMaine
37K Followers 881 Following Keep up to date on all of the latest news from Sugarloaf, the largest ski and snowboard resort in the East.Stratton Mountain @StrattonResort
18K Followers 2K Following A Bold Mountain Community Cultivating Extraordinary Experiences. Stratton, VT Tag your Stratton adventures with #StrattonMountainWachusett Mountain @Wachusett
8K Followers 579 Following The most accessible ski resort in the East! Tag your photos #Whychusett Terrain Park updates: @wachusettparksSammy Tse @tse_elegans
128 Followers 213 Following Graduate student at UMass Chan studying intestinal innate immunity in C. elegans.Craig Crews @CraigMCrews
9K Followers 1K Following Yale Professor, Founder of @ArvinasInc, https://t.co/YoR6Yo3d3u Mastodon account: @[email protected]OpenAI @OpenAI
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156 Followers 117 Following Beginner on Twitter, Assistant Professor at @dankook_int #Cancer researcher, #Cancer metabolism, #Ferroptosis, #Nutrient metabolism, #Toxic metaboliteJason Kelce @JasonKelce
588K Followers 48 Following Authenticity is hard to find, come get your dose of real. Posts are indicative of my values, opinions, and stories. @newheightshow @underdog_phlIan Cannell @IanGCannell
3 Followers 24 FollowingKamyar Hadian @HadianKamyar
563 Followers 1K Following Research Group Leader @HelmholtzMunich | #Ferroptosis #Ubiquitin #CellSignaling #CellDeath #ChemicalBiology #DrugDiscovery | Proud Dad, Husband to @M_VincendeauSean Rudd @Rudd_SG
681 Followers 1K Following Group Leader @karolinskainst @scilifelab | @GDSC_sussex alumnus | Focused upon improving cancer treatment | [email protected]University of Washing.. @UW
187K Followers 2K Following University of Washington students, faculty and staff believe in boundless opportunities. Do you dare to Be Boundless? At the UW, you can.Triona Ní Chonghaile @NiTriona
1K Followers 874 Following Cancer Biologist that likes killing cells - cancer cells. A Senior Lecturer at the Royal College of Surgeons in Ireland. Comments are my own.Zhe Wang @ZheWang_NCB
389 Followers 29 Following Senior Editor @NatureCellBio ([email protected]) | #cancerresearch #immunology #celldeath | My own viewsIsaac Harris @isaac_s_harris
3K Followers 3K Following Assistant Professor @UR_med @Wilmot_Cancer. The Harris Lab works to understand the roles of #antioxidants in disease. Views are my own.The Night Science Pod.. @nightsciencepod
3K Followers 46 Following The Night Science podcast explores the untold story of the scientific creative process, with your hosts @ItaiYanai and @MartinJLercherStevens Pass @StevensPass
37K Followers 525 Following Epic snow, exciting terrain, & excellent community since 1937.Washington Football @UW_Football
217K Followers 813 Following *infinite* PAC 12 CHAMPIONS 🏆 x2 National Champions 📈 x18 Conference Champions #PurpleReign ☔️Ku-Lung Hsu @Hsu_Lab_UVa
873 Followers 375 Following Ku-Lung (Ken) Hsu is an Associate Professor of Chemistry at the University of Texas AustinMarraffini Lab @MarraffiniLab
2K Followers 39 Following News from the Marraffini Lab @RockefellerUnivPostdoc Brewing @postdocbrewing
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92 Followers 192 FollowingFrontiers in Systems .. @FrontSystemsBio
478 Followers 329 Following We've moved! Please follow our new account @FrontBioinf for updates on Frontiers in Systems Biology.Ryan Logan 🧠 21. @wickedneuro
3K Followers 4K Following Professor | Sleep, Circadian Rhythms & Psychiatric Disorders | @UMassChan @UMassPsychiatry @NeurobioUMassScott Leighow @ScottLeighow
98 Followers 210 Following Postdoc in the Pritchard Lab at Penn State | Research in synthetic and systems biology of anticancer drug resistance | 2006 Times Person of the YearWorcester Red Sox @WooSox
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10K Followers 268 Following The proud home of the @WooSox, located in the Canal District of Worcester, MA.Steven Salzberg 💙�.. @StevenSalzberg1
19K Followers 235 Following Bloomberg Distinguished Professor of BME, CS, and Biostats at Johns Hopkins University, tennis player, blogger at Forbes: https://t.co/7SZhlbYPtn…Peter Bruno @petes_tweets0
194 Followers 160 FollowingIconic Sonics @Iconic_sonics
3K Followers 558 Following Sharing stories of the SuperSonics and Seattle hoops. Presented by Truth + Media (@truthplusmedia) #BringBackOurSonics 💚💛Kahlilia Morris-Blanc.. @MorrisBLab
410 Followers 387 Following Assistant Professor @PennCDB @PennEpiInst Neuroscientist who loves #epigenetics and #mitochondrialbiology Researching ways to prevent brain damage after strokeTigist Tamir @TigistTamir
652 Followers 955 Following Postdoc @kochinstitute @MITBPG|| Metabolism & cell signaling: I'm about omics,☕, 💃🏾, & TT|| PhD: @UNCBBSP @UNCIMSD|| @Edges_and_Nodes| 🤳🏾My opinionsEmily Lowry @emily_lowry23
40 Followers 15 FollowingClaus Jorgensen 🇪�.. @claus_jorgensen
2K Followers 2K Following Group Leader @CRUK_MI 🇬🇧. Focus on tumour stroma, cell signaling and pancreatic cancer. My opinion etc etcThe PI's contribution to the paper
Our new paper on “synpoptosis” circuits, led by the amazing @ShiyuXia, is now out: sciencedirect.com/science/articl… (1/3)
Check out our new work on GEFMAP which predicts metabolic flux in bells from transcriptional measurements using geometric deep learning! presented @RECOMBconf today!! Lead by Holly Steach and Siddharth Viswanath! github.com/KrishnaswamyLa…
R01 funded. Exhale. Normalizing rejection: Submitted 1st R01 in Feb 2019 & then nearly every cycle after. 6 unique proposals & lots of resubmissions. More scores in 30s than I can remember. Funded R01 was 6th submission of idea. I cried when I saw 2nd percentile Lessons learned:
Dear students, Learn to code. This is the best way to know exactly what happens to your data. It allows you to pursue your creative ideas and to implement the analysis you want to do.
Exited to share our new paper by Gang Du @ , Liam @L_Heals, Liron David @LironDavid2 and others on GSDMD palmitoylation. “ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D” in Nature nature.com/articles/s4158…. Even full-length GSDMD can form pores!
@arjunrajlab @baym Ok I’m really sorry to do this but I have what the kids refer to as receipts
New and improved response in my Annual Faculty Report to what I find fulfilling in my work life: I find all aspects of my work life fulfilling except for filling out bureaucratic paperwork and walking through metal detectors to get to my laboratory.
say it together #bringbackoursonics
Defense Days are the BEST!! To no ones surprise, @UMassChan @UMassMDPhD student @tse_elegans successfully defended her 3 first author paper, 350-page thesis. She is such a ⭐️!! Our lab’s 5th PhD defense in the last 5 years! #ProudPI
Well, this is exciting. Grateful to @UMassChan for being such a wonderful place to work.
Our paper on functional discovery of protein degradation and stabilization effectors with proteome-scale induced proximity screens is out in its final version! 1/ nature.com/articles/s4158… rdcu.be/dBUju
I'm shocked the guy who thought Dean Phillips would win Michigan finds @elonmusk's propaganda video credible Here are some arguments, Bill: 1) It is illegal for non-citizens to vote in federal elections, and they don't, because you need a license or SSN to register 2) All…
I find this credible. What are the best arguments one can make against the case the video makes?
Just received the NoA for the lab's 1st R01! On top of this we were fortunate enough to be converted to an R37, giving us 2 extra years of funding. Could not have done this without great mentors, collaborators, and our team. Feels unbelievable to know we are funded through 2031!
Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome…
@TheLeeLab @nchembio @meganhoneywell @UMassChanGSBS Congratulations @TheLeeLab and @meganhoneywell for publishing this beautiful work!
Congrats @meganhoneywell and @TheLeeLab 👏 Thanks for including me in this great project.
Our MEDUSA paper was published today in @nchembio! This is an approach for identifying death-regulatory genes, which we used to clarify different ways cells die following DNA damage. Congrats to @meganhoneywell @UMassChanGSBS and to the other authors! rdcu.be/dA4uj