TILs Working Group @TILsWorkGroup
We are interested in the immune infiltrate in Breast cancer and what it means for treatment and prevention. tilsinbreastcancer.org All over the world Joined December 2017-
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Such a privilege to be part of the international TIL Working Group @TILsWorkGroup and to collaborate with Dr. Salgado on NeoTIL. #SABCS @muschollings @stolaney1 @OncBrothers @LoiSher
@TILsWorkGroup moves into our AI era #sabcs2025 #tils @OncoAlert
Amazing presentation by Roberto Salgado from @TILsWorkGroup TIL assessment of APHINITY using CASE45 AI model and manual TILs (great ICC) Combining AI and manual assessment is a better prognostic biomarker than either one of them
TILs matter in HER2+ BC! In ShortHER trial, mapping their spatial organization with AI assessing: 🔹Immune-tumor interaction 🔹Aggregates/TLS (Hotspots) further refines prognosis beyond manual evaluation PS2-08-11 at #Sabcs25 @UniPadova @iov_irccs @TILsWorkGroup
Tagging @TILsWorkGroup to amplify this great work
✨✨hot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention. 👏👏Thanks to @FAndreMD @DrChoueiri
✨✨hot off the press from the #loilab. We show here that pregnancy & breastfeeding is associated with increased T cells in the normal breast and protection against #tnbc #breastcancer moving the role of immunity from treatment to prevention. 👏👏Thanks to @FAndreMD @DrChoueiri @MyriamChalabi for the opportunity to present #ESMO25 @OncoAlert @myESMO @PeterMacRes @PeterMacCC @UniMelb thanks to our funders @BCRFcure @TheMarkFdn @NBCFAus @Nature Article is here: nature.com/articles/s4158…
Translational data shows that #breastfeeding helps personal immunity improving CD8+ T This work can help to understand better the immune system and breastfeeding mechanisms @LoiSher @OncoAlert #ESMO25 @FernandoOnco
The EU-funded MSCA Doctoral Network “Spatial Crosstalk in Immune-Oncology” (SpaXio) is now officially recruiting 14 PhD students to decipher the metastasis-promoting microenvironment of colon and breast cancer. More info here: tilsinbreastcancer.org/wp-content/upl…
😎if #TIL had been the prespecified biomarker, pembrolizumab might well be approved for this indication. PD-L1 IHC has real technical limitations- patients deserve multiple validated ways to identified immune enriched tumors. #TILs are simple, free & readily available- wait 🤔is that the problem? @oncoalert @TILsWorkGroup #bcsm
💫🌟Association of potential biomarkers with clinical outcomes in metastatic TNBC treated with pembrolizumab or chemotherapy 👉 nature.com/articles/s4152… @JavierCortesMD @ProfAnthoG @ASCOPres @Prof_Nadia_H @LoiSher 🧬 KEYNOTE-119 exploratory biomarker analysis 🔹 TILs ≥5% → ↑
Study across 45 institutions shows AI validity in TIL quantification for melanoma. Reproducible with prognostic validity and open-source. @tznaung 👉 jamanetwork.com/journals/jaman… #AIinPathology #Melanoma #ComputationalPathology
Some studies shows how we can reduce costs based on biomarkers SHORT-HER 9 weeks of trastuzumab is ✅ based TILS 20% or more @TILsWorkGroup @OncoAlert #oncoalertAF @JAMAOnc⤵️ jamanetwork.com/journals/jamao…
📄 Pitfalls in ML-based TIL assessment 🔗 doi.org/10.1002/path.6… 📄 Spatial analyses of immune infiltration in cancer 🔗 doi.org/10.1002/path.6… #ImmunoOncology #DigitalPathology #TILs
🎉 Thrilled to share that 2 @JPathol papers from the TILs Working Group ranked in the Top 10% most-viewed in 2023! 👏 Huge thanks to all collaborators, @JPathol & our readers for your support. 📎 Links in comments ⬇️ #TopViewedArticle #TILsinBreastCancer #pathology
Great slide highlighting not only are TILs predictive of pCR...it also translates to being prognostic beyond pCR for good outcome and DFS. Seems like we have a LOT of data on TILs now, why aren't they standardly provided on path reports???🧐 #SABCS24 @SABCSSanAntonio @OncoAlert
Celebrating 10yrs of #til in #BreastCancer #sabcs24
🤩🍾10th anniversary TILs-Working Group at @SABCSSanAntonio 2024 - everyone welcome! RSVP here: forms.office.com/Pages/Response…
The largest TILs-Workshop done so far! More than 100 pathologist, residents in training and medical students learning how to score TILs. Organized by the Narayana Medical College, India. Who follows? 💪🏼
Join us for the 2024 Peter Mac Breast Cancer Medical Oncology Education Day! 📅 On Friday, 11th October, dive into the latest in breast cancer care with experts at Peter Mac or via Zoom. Registrations: shorturl.at/fpr82 @PeterMacRes @PeterMacCC
🤩Check out latest article in @NatureRevCancer! #TILsInBreastCancer #Researchpaper
Towards targeting the breast cancer immune microenvironment dlvr.it/T9C7GF
Our latest review is out now on targeting #BreastCancer #Immunity #tme #trm #CancerResearch many thanks to @NatureRevCancer @PeterMacCC @PeterMacRes @TILsWorkGroup
Towards targeting the breast cancer immune microenvironment dlvr.it/T9C7GF
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