Simon John Lab @SimonJohnLab
Our lab investigates molecular features of #glaucoma @Columbia . Tweets from members of the lab. simonjohnlab.org New York, NY Joined September 2020-
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New Nature Communications paper: Elevated IOP causes vein-specific BRB breakdown in glaucoma, associated with MFSD2A loss and increased endothelial transcytosis. Stabilizing endothelial β-catenin reduced leakage and mitigated neurodegeneration. nature.com/articles/s4146…
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🧐New study: pyruvate and related metabolites may boost resilience to glaucoma in individuals with high genetic risk. Read the article here: elifesciences.org/reviewed-prepr…
This article was just published in Nature Communications. Congrats, @cubical and @SimonJohnLab! Hard work pays off! nature.com/articles/s4146…
👁️Our latest preprint is out! We reveal an exciting, previously overlooked mechanism contributing to glaucoma pathogenesis: IOP-induced blood-retinal barrier breakdown. Check it out here: biorxiv.org/content/10.110…
🚨📜Check out our latest preprint: "TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma" biorxiv.org/content/10.110…
Simon John Lab retweeted
Paper Alert- new preprint dropped- awesome collab with @LadyGlaucoma and @SimonJohnLab - multimodal sequence profiling of the mouse #Schlemmscanal and more-tweetorial to follow!! biorxiv.org/content/10.110…
The Department of Ophthalmology is seeking a Staff Associate to work in a dynamic experimental genetics laboratory at Columbia University with duties at the Manhattanville campus. The laboratory focuses on the genetics, pathophysi…lnkd.in/eYxyTKyx lnkd.in/eDxYBV6Z
I’m #hiring. Know anyone who might be interested? lnkd.in/eU7zDsWE
The John Lab is #hiring ! Check out our Research Associate I posting and come work with us at Columbia University: opportunities.columbia.edu/en-us/job/5165… Please RT
The John Lab is #hiring ! Check out our *updated* Research Associate posting and come work for us at Columbia University: opportunities.columbia.edu/en-us/job/5137… Please RT.
The John Lab is #hiring ! Check out our *updated* Colony Manager posting and come work for us at Columbia University: opportunities.columbia.edu/en-us/job/5137… Please RT.
@Asim10885531 Asim, I would love to hear from you. Please apply at opportunities.columbia.edu/en-us/job/5120…
The John lab is hiring! 2 Research Associate positions available. Come work with us in Columbia University. For more info, to apply: opportunities.columbia.edu/en-us/job/5122… . opportunities.columbia.edu/en-us/job/5121… Please RT.
What we do: Cool glaucoma research. What we need: Dedicated and motivated applicants. What we offer: A competitive salary, training, mentorship, and a boost to your career.
The John lab is hiring a mouse colony manager! Come work for us at Columbia in vibrant NYC. The position will provide exposure and training in areas including mammalian genetics, neuroscience, molecular biology, and physiology! For more info, to apply: opportunities.columbia.edu/en-us/job/5120…
Another recent publication: dmm.biologists.org/content/early/… Study led by Nick Tolman identifies differential vulnerability to glaucoma in Lmx1b mutant mice.
Highlighting recent publications from our lab: pubmed.ncbi.nlm.nih.gov/33318177/ An excellent study led by @pete_the_teapot and Jeff Harder on disturbed metabolism in glaucoma and protection by rapamycin.
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