Jonathan Schertzer (SchertzerLab) @SchertzerLab
Immunometabolism research: Diet, microbes, drugs and hormones McMaster University Joined December 2012-
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Advancing precision health discovery in a genetically diverse health system cell.com/cell/fulltext/…
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Distinctive DNA sequence features define epigenetic longevity of inflammatory memory science.org/doi/10.1126/sc…
Jonathan Schertzer (SchertzerLab) retweeted
Take a short break to review today's Mini-Review #ArticleinPress, Immunometabolism of IRF4 in Adipose, #Muscle, and Immune Cells Influences #Obesity and MASLD (Daniel Marko and Jonathan Schertzer @McMasterU): ow.ly/BCin50Yyghs
Genomic atlas of Bifidobacterium infantis and B. longum informs infant probiotic design cell.com/cell/fulltext/…
Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis cell.com/cell/fulltext/…
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma cell.com/cell-host-micr…
Jonathan Schertzer (SchertzerLab) retweeted
TRIPping anti-tumour immunity through lactylation dlvr.it/TRHR2b
Preprint: CRY-NLRP3 complexes define a circadian checkpoint controlling inflammasome activation biorxiv.org/content/10.648…
Targeting microbiota-generated acetaldehyde to prevent progression of metabolic dysfunction-associated steatotic liver disease cell.com/cell-metabolis…
Jonathan Schertzer (SchertzerLab) retweeted
Insulin and adipocyte IRF4 promote fat retention over muscle preservation during intermittent fasting in obesity dlvr.it/TR7qyl
Insulin and adipocyte IRF4 promote fat retention over muscle preservation during intermittent fasting in obesity cell.com/cell-reports/f…
Jonathan Schertzer (SchertzerLab) retweeted
New! Online now: Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis dlvr.it/TR6mSR
Hepatic adaptation to chronic metabolic stress primes tumorigenesis: Cell cell.com/cell/fulltext/…
Jonathan Schertzer (SchertzerLab) retweeted
In humans nighttime metabolic dysfunction is a hallmark of #MASLD with multiple pathogenic pathways upregulated at night, including hepatic and peripheral insulin resistance, DNL, and systemic NEFA exposure cell.com/cell-metabolis… #circadian
Jonathan Schertzer (SchertzerLab) retweeted
Jonathan Schertzer (SchertzerLab) retweeted
Great time at the #NeurIPS2025, especially the chance to discuss our collaborative work with the @SchertzerLab and @Ali_Etemad1 and to connect with AI experts pushing time-series methods for health. I really enjoyed catching up with friends and colleagues: @Zjahed, @JWangnano
Jonathan Schertzer (SchertzerLab) retweeted
Previously shared: Let’s GIV a NOD(2) to gut homeostasis Here, Pradipta Ghosh & team @UCSanDiego find a critical interaction between GIV and NOD2 in gut macrophages, revealing their importance in maintaining gut health and preventing inflammatory bowel diseases (#IBD): doi.org/10.1172/JCI190… The TEM images show phagolysosomal fusion events in infected macrophages from WT mice but not those from those lacking GIV.
T cell cholesterol transport links intestinal immune responses to dietary lipid absorption science.org/doi/10.1126/sc…
Jonathan Schertzer (SchertzerLab) retweeted
Inflammation is a key driver of the pathophysiology of cardiometabolic disorders #obesity #T2D and new metabolic medicines based on GLP-1 action exert their magic in part by reducing inflammation. A new review from Professor Donath summarizes the field sciencedirect.com/science/articl…
A salute to innovation: exenatide in diabetes and obesity drug development at Amylin Pharmaceuticals nature.com/articles/s4225…
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