Nazish Sayed MD, MS, PhD @Nazish_Sayed
Associate Professor @StanfordCVI @stanfordvasc @StanfordSurgery interested in #Endothelial & #Vascular Biology, #CardioOncology, and Reg Med. #Cancer survivor profiles.stanford.edu/nazish-sayed Stanford, CA Joined February 2015-
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Nazish Sayed MD, MS, PhD retweeted
When Blood Vessels Trigger Heart Failure Researchers at CVI have identified a new mechanism driving LMNA cardiomyopathy: endothelial cells undergo a dramatic identity change that promotes cardiac fibrosis and dysfunction. @Nazish_Sayed Read more here: med.stanford.edu/cvi/mission/ne…
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Folks, our new study in European Heart Journal @ESC_Journals @ehj_ed RUNX1-driven endothelial-to-mesenchymal transition contributes to remodelling in LMNA cardiomyopathy academic.oup.com/eurheartj/arti… Team effort @StanfordCVI @StanfordSurgery @StanfordVasc @stanfordctsurg
@NickLeeper78 @StanfordVasc Thank you Nick for all the support.
Nazish Sayed MD, MS, PhD retweeted
The ion channel protein #PIEZO1 protects against cardiac injury during #cancer treatment with tyrosine kinase inhibitor #TKI #sunitinib, according to a new study in mice and patient-derived #endothelial cells. @StanfordMed scim.ag/4pGBFPv
Excited 2 start 2026 with a review in @VMJ_SVM on #iPSC based #NAMs (#Vascular #Organoids, #multiomics) for rare vascular disease. Thx 2 Lu Liu David Wu PhilTsao @NickLeeper78 for Collab & @Joseph_C_Wu @maryhawn @StanfordSurgery 4 support. #RareDisease journals.sagepub.com/doi/10.1177/13….
Nazish Sayed MD, MS, PhD retweeted
#Sunitinib is an effective cancer treatment, but exposure can result in #hypertension & #HeartFailure. Dr. @Nazish_Sayed's lab at @StanfordCVI restored #PIEZO1 expression to reverse sunitinib-induced #endothelial dysfunction. 🔖 bit.ly/4s9xrBG 🗨️ bit.ly/4pOTLib
Nazish Sayed MD, MS, PhD retweeted
In this new @ScienceTM study from the lab of Dr. @Nazish_Sayed at @StanfordCVI, researchers identify a role for PIEZO1, a mechanically activated ion channel, in tyrosine kinase inhibitor-induced #cardiotoxicity and present a potential avenue for prevention. 🔗 bit.ly/4s9xrBG
Nazish Sayed MD, MS, PhD retweeted
When life-saving cancer drugs put the heart at risk New research from @StanfordCVI reveals how TKI sunitinib disrupts blood vessels’ ability to sense blood flow, driving hypertension & heart damage. Read more: med.stanford.edu/cvi//mission/n… @Nazish_Sayed, @StanfordSurgery, @ScienceTM
Thx to collaborators @amitmanhas07, Yu Liu, Noishiki, David Wu, Tripathi, Sarah Mirza, @iDilipThomas, Lu Liu, @avirupguha , Nguyen, Chen, Chitalia, Cheng, @dannysayed, @melindatelli, Karim Sallam, @Joseph_C_Wu Thx @Amanda_J_Chase for this amazing write up. cvi.stanford.edu/mission/news_c…
Excited 2 share our new paper @ScienceTM. V show how a cancer drug disrupts blood-vessel #mechanosensing via #PIEZO1, driving #hypertension & #cardiac dysfunction & how restoring #endothelial function protects🫀 @Joseph_C_Wu @maryhawn @StanfordSurgery science.org/doi/10.1126/sc…
Nazish Sayed MD, MS, PhD retweeted
Baszucki Research Day 2025 ✨ We welcomed Dr. Ulf Hedin from Karolinska Institute as our Baszucki Visiting Professor. From dinner with faculty & residents to a keynote on precision medicine, Biobank tour, & Grand Rounds on biobanking—what a week of innovation & collaboration! 🔬
Nazish Sayed MD, MS, PhD retweeted
Stanford researchers led by Drs. @NickLeeper78, @Nazish_Sayed, & @EriFukayaMD have developed an induced pluripotent stem cell (iPSC) line from a patient with varicose veins — paving the way for in vitro modeling of venous disease. 🔗: brnw.ch/21wWImM
Sharing our recent review @JMCCardiology We discuss how #LongCOVID drives cardiovascular complications & highlight the promise of #NAMs, #iPSC, #organoids & #AI in advancing diagnostics & therapies. @iDilipThomas @Joseph_C_Wu @StanfordCVI @StanfordSurgery jmcc-online.com/article/S0022-…
Came home to this beautiful surprise — truly touched by the kindness and support 🌸 Grateful to @StanfordVasc @StanfordSurgery @StanfordCVI @maryhawn @Joseph_C_Wu @RLDalmanMD for supporting this promotion! Thx #Sayed Lab and friends @iDilipThomas @amitmanhas07 @chun_liu_86
@StanfordDeptMed @StanfordMed Congratulations Karim. So well deserved.
Nazish Sayed MD, MS, PhD retweeted
🧬 iPSCs shed light on vascular Ehlers-Danlos syndrome—Dr. Lu Liu brings new insights from endothelial cell modeling. @Nazish_Sayed #Holman25
Thank you @CircAHA for highlighting our recent paper on LMNA-related Dilated Cardiomyopathy. Need more studies that repurpose already FDA approved drugs for existing cardiac diseases @StanfordCVI @StanfordSurgery @SeanM_Wu @Joseph_C_Wu @josephahill @heshamasadek @American_Heart
Olmesartan may provide targeted, mutation-specific therapy for HF patients with an LMNA mutation @SeanM_Wu @Nazish_Sayed @SJovinge ahajournals.org/doi/full/10.11…
"Teaching old drugs new tricks! Folks, our paper in @CircAHA explores repurposing olmesartan for LMNA-DCM using #iPSC-derived CMs and leveraging NIH funded @LINCSProgram data. @Joseph_C_Wu @SeanM_Wu @chun_liu_86 @maryhawn ahajournals.org/doi/10.1161/CI…
Congrats 🥂 to @StanfordCVI researcher @Nazish_Sayed on a @CircAHA paper identify a #DrugRepurposing candidate for treating heart disease, found by analyzing gene expression in diseased hearts med.stanford.edu/cvi/mission/ne… @StanfordMed @StanfordSurgery @StanfordVasc @StanfordDeptMed
@ArunSharmaPhD @CSRegenMedicine Awesome. Congrats Arun.
Great lab and great mentor.
Yin lab is recruiting for positions at the University of Arizona, College of Medicine, Phoenix. If you’re interested in coronary microcirculation in diabetes and Heart Failure, please join us! Researcher/Scientist - arizona.csod.com/ux/ats/careers… Postdoc - arizona.csod.com/ux/ats/careers…
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