Mostoslavsky Lab @MostoslavskyLab
The Mostoslavsky lab at Harvard & Mass General Cancer Center. We study chromatin, cancer, metabolism, DNA repair, PTMs et al. Tweets are from anyone in the lab! mostoslavskylab.mgh.harvard.edu Boston, MA, USA Joined April 2018-
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Following478
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@jdelriopantoja @HarvardGSAS @MGHCancerCenter Excellent article Jose!! proud to have you in my lab!!
Thanks @HarvardGSAS for featuring my story going beyond the dogmas of life. Cannot wait to formally share with the world all the cool science we’re doing at the @MostoslavskyLab @MGHCancerCenter. gsas.harvard.edu/news/beyond-do…
We’re happy to share our new study out today @NatureCellBio We show that a chromatin factor, ZNF280A, is required for DNA double strand break repair, linking its absence to clinical features in 22q11.2 distal deletion syndrome. @MostoslavskyLab nature.com/articles/s4155…
Excited to share our new work on how DNAJB1-PRKACA drives cancer cell growth in Fibrolamellar Carcinoma. @CD_AACR Thanks to all our collaborators and funding support. @FibroFoundation @AICF_nyc @DonaBertarelli @ForbeckForums @AlexLemonade
Now online in @CD_AACR: DNAJB1-PRKACA Drives #Fibrolamellar Liver Cancer via Impaired SIK Signaling & CRTC2/p300-mediated Transcriptional Reprogramming - by @IlariaG32, @DoransRing6012, Taranjit Gujral, Nabeel Bardeesy, et al. doi.org/10.1158/2159-8… @fredhutch @MGHCancerCenter
New Research: Subcellular one carbon metabolism in cancer, aging and epigenetics frontiersin.org/articles/10.33… #FrontiersIn #Epigenetics #Epigenomics
Really happy to share our new mini Review on One Carbon Metabolism and chromatin (fantastic job by @Tiz_bernasocchi. Out in @FrontGenetics frontiersin.org/journals/epige…
New in @ScienceMagazine! Our study reveals how mutant IDH1 inhibition activates tumor immunity by inducing dsDNA sensing. Read more: science.org/doi/10.1126/sc… #CancerResearch #Cholangiocarcinoma #IDH1 1/n
Our lab does a little bit of everything centered around chromatin biology and metabolism. No previous research experience needed, but preferred!
This will be a full-time research technician position, roles will include assisting with basic science techniques, from standard molecular biology to advanced biochemistry, genetics, and in vivo work.
The Mostoslavsky Lab is looking for a highly motivated Research Technician interested in being part of our team for at least two years! Please share with your networks, and/or apply by sending an intro email with CV to: [email protected]
@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Ha ha! not sure I spoke about oncometabolites in the talk! :) We can chat about 2HG, probably the best oncometabolite example of how it affects chromatin by inhibiting all the a-KG dependent dyoxygenases.
Online now!! Really thrilled to share our latest work identifying a novel driver of metastasis, Gstt1, @NatureCellBio. A huge effort lead by Christina Ferrer and an incredible team of collaborators!! link.springer.com/article/10.103…
@NCIYaminiDalal @NatureCellBio @NCIResearchCtr @WeyemiLab It was a pleasure to see you all there!!
@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Thanks Yamini!!!!
@JAguirreGhiso @NatureCellBio Ehhh! Thanks Julio!! so happy it is out! You heard it long ago!
@Lloyd_Bod @NatureCellBio Thanks Lloyd!!
@sciqst @NatureCellBio Thanks Raffaele!!!
@FrezzaLab @NatureCellBio Thanks Christian!!
@FendtLab @NatureCellBio Thanks Sarah!!!
@BarakRotblat @NatureCellBio Thanks Barak!
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