Kendra Marcus @Little_Machines
Postdoc at UC Berkeley/Vanderbilt. Lady scientist. Enthusiast of tiny things. Enthusiast of humanity. Berkeley, CA Joined December 2020-
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We made the cover of @cellsystems! Elementary landscapes for two fitness functions reveal that combining them creates a more rugged landscape. This highlights the demand on a DNA-binding domain to evolve affinity for distinct half-sites @Jackson_Lab tinyurl.com/yc2web9a
Happy to share that our latest paper led by @chrfrohlich and @AdrianBunzel is out @NatureCatalysis. If you like protein evolution and epistasis, this paper will give you interesting insights; Shifting the rate-limiting step can cause strong epistasis. nature.com/articles/s4192…
Happy to share the preprint of my first research paper from grad school on how the epigenetic silencer PRC2 is inhibited by histone modifications found at actively transcribed genes - check out the thread for more details!
Happy to share the preprint of my first research paper from grad school on how the epigenetic silencer PRC2 is inhibited by histone modifications found at actively transcribed genes - check out the thread for more details!
Thank you for featuring our work, @VUBasicSciences! medschool.vanderbilt.edu/basic-sciences…
Looking for useful hacks for brand new labs (biochem focused) 🧬🔬⚗️
scholpp_lab @scholpp@.. @scholpp_lab
1K Followers 3K Following Gonzo Scientists are interested in cell-cell signalling and cell migration in zebrafish development and diseases. You find us also @[email protected]Brandon. @ProfBrando369
78 Followers 508 FollowingStephanie Rusew @SteRusew
6 Followers 84 Following Neuroscience PhD student at USP. Neuroendocrinology research on food intake, energy balance, reproduction and stress. She/herNational Technology A.. @NTA_360
3K Followers 5K Following We expedite the economic and societal impacts of government and commercial investments in innovative technologies. Join us.Philippe Djientcheu @DjientcheuP
25 Followers 118 Following PhD student 🧠 Neuroscientist at University of Yaoundé I, T2D-related brain complications (cognitive and locomotor disorders), Brain-bone crosstalk in T2DGonzalo Moratorio @gonzamoratorio
41K Followers 3K Following Evolutionary&Molecular Virologist doing Science from SouthAmerica🇺🇾/ Featured @Nature's10:Shaping Science 2020/GroupLeader @IPMontevideo /Assoc.Prof @UdelaruyHossein GHAF @HosseinGhaf
1K Followers 246 Following Atheist, Biologist, Fighting against Islamic apartheid in Iran and couple of other things.Molamin drammeh ✝�.. @DarboeFakk90452
136 Followers 4K Following The Lord makes poor and makes rich; he brings low and he exalts.Lu Chen @luchenlab_FCCC
564 Followers 1K Following Assistant Professor https://t.co/C1RcAPDAyY @foxchasecancer @CeiFccc studying RNA biology in diseases; trainings @ScienceStowers and @Stanford.Sharon Lewis @SharonLewi20942
3 Followers 159 FollowingFardin Nabizadeh @fardin_nb
178 Followers 417 Following Dementia Researcher| Neurobiology | Neuroimaging 🧠 IUMSKarolinekiddine @Oranahca
678 Followers 3K Following Social Justice, Spirituality, Agriculture, Communication, Psychology, Problem Solving, Community, Philosophy, Gardening, Family, Education, WritingKonduru Ashok Kumar R.. @Ashokkumarrajuk
21 Followers 544 Following Ph.D Research Scholar, Materials Science & Engineering (Biomaterials), Asst. Professor, Mechanical Engg. Dept., JNTUA, Philosopher, Motivator, CriticTravis Millard @millard_tr3567
37 Followers 499 Following Orthopedic surgeon doctor working on high sea with the engineersYuliana Castañeda @bioyunita
215 Followers 2K Following Biologist @FCienciasUNALco - MSc. Biotechnology @UNALmedellin, 🇨🇴 #ConservationGenetics #eDNA @inst_humboldt #MolecularMicrobiology #GodfollowerSandeep Kumar @Sandeepkum20492
27 Followers 97 Following Ph.D. #Himalayan river @ HNBGU. Hydropower impacts#benthic diatoms#macroinvertebrate#ichthyofauna. https://t.co/ZShfomy1KNMapleleaf @Mapleleaf123676
0 Followers 22 FollowingTarjani Thaker @tarjanithaker
163 Followers 362 Following Assistant Professor in @Biochem_Chem @uarizona. #StructuralBiology and #MembraneProtein fanatic! Former @JuraLab_UCSF Postdoc, #Vanderbilt PhD. We're #hiring!Thomas Allen @thomas_all41494
76 Followers 1K Followingdodie salma @dodiesalma
6 Followers 88 FollowingCorynne Adanho @AdanhoCory30912
15 Followers 533 Followingbridget (Briggie ) bo.. @BridgetBoba
125 Followers 491 Following Entomologist (Insect pollinators: Bees, butterflies and beetles)/ Chemical Ecologist/ One Health30-50 Farrell Dobbs @PSolidarity08
2K Followers 2K Following Colombian 🇨🇴 Teamster ✊ Marx was right.ANIK KUMAR DEY @ANIKKUMARDEY6
49 Followers 3K Followingarathi @nayerarathi
1 Followers 4 FollowingNelson Abarca @NelsonRAbarca
118 Followers 645 Following Neurology Research Technician at MGH | FIU BS in BME 21' My opinions are my own. #blacklivesstillmatterBioInspired Syracuse @SUBioInspired
537 Followers 459 Following BioInspired Syracuse supports research into complex biological systems to address global challenges in health, medicine, and materials innovation.Ritika Saxena 🩸(I .. @RitikaSxn
717 Followers 2K Following 👩🏻🔬🇦🇺PhD @unimelb 🧫 Stem Cells/Blood @AndrewElefanty @MCRI_for_kids @reNEW_global 💸 Scholar ArrowBMT 🎤Conversations @StemCellsUoM 🌼 DEI @ISEHSocietyMythily @Mythilyvasudeva
19 Followers 539 Following Project assistant at National Brain Research Centre,Manesar# Neurobiology.Fatemeh Baghban @FatemehBaghban2
31 Followers 202 Following Master’s in Medical Biotechnology, I’m interested in Cancer Biology,Genetics and BioinformaticsJennifer Dowling @DowlingJK83
751 Followers 560 Following Lecturer and PI @RCSIPharmBioMol @FutureNeuro_ie Working to understand the NeuroImmune axis & inflammation in the brain @BrainInflamIEhussain @hussainzahrani3
75 Followers 510 Following a researcher, answering mini research questions in translational/applied sciences, neurosciences*, and neurobiological research,ephysiological modificationxx @dadadasod
2 Followers 49 FollowingRENATO | REGENERATION @RENAT0dosSANT0S
65 Followers 334 Following #Scientist sharing the latest advancements and raising awareness in Regenerative medicine. ⁉️Curiosities 💉Treatments 📰Articles 🧬ServicesTumpa Mahanty @MahantyTumpa
51 Followers 423 Following IIT Ropar|| Master's in Chemistry || Summer Intern @ IISER Kolkata || BHU AlumniJulianna Mendez @mariejulianna_
352 Followers 899 Following PhD student with @HokeCSU | 👩🏻🔬🧠 🐁🐸🐍 | studying communication in tropical frogsNoah Hull, PhD, MPH @NoahHull_PhD
747 Followers 1K Following Public health practitioner 👨🔬 | UAB 🐲 | UW 🤠 | Global Health | Expressed views are mine and do not represent the views of my employer. RT =/= endorsementYuri Malina @ymalina
834 Followers 575 Following Former entrepreneur @design4america and @SwipeSense. Budding scientist at the Meyer Lab at UC Berkeley.Anubhav Dhar @anubhav_dhar
319 Followers 896 Following Grad Student @IISc Bengaluru. BS-MS with major in Biology @IISER Tirupati. Interested in science, sports, politics and everything else that is interesting.Zachary Taylor @ZTaylor7220
58 Followers 111 FollowingSeoyeonLee @seoyeonlee_
55 Followers 433 FollowingJose Alex Rodrigues, .. @JoseARodrigues8
924 Followers 3K Following PSTDP Intern @KidsAtColumbia, @CheAndamMicro and @Manning_Lab Alum, Microbial Genomics, Eco, Evo, Epi, @A_P_S_A Past Prez. Proud Dog Dad! Views are my own.Hemanathan @Hemanat83470597
1 Followers 255 Following In the face of impossible we all are inspired.New PI Slack @NewPI_Slack
13K Followers 1 Following A community of new science PIs helping each other survive & thrive. To join: https://t.co/LD14QPvfz2 Photo by NASA/JPL/University of Arizonascholpp_lab @scholpp@.. @scholpp_lab
1K Followers 3K Following Gonzo Scientists are interested in cell-cell signalling and cell migration in zebrafish development and diseases. You find us also @[email protected]Antje Schaefer @AntjeSchaeferZ
362 Followers 530 Following Research Assistant Professor @UNC_Lineberger @unc_PHCO @derlabunc 🇺🇸 | PhD @mpimoph 🇩🇪 | RHO & RAS #GTPase signaling in #cancer (gastric, pancreatic, lung…)Sebastian S. Cocioba�.. @ATinyGreenCell
24K Followers 8K Following Amateur 🌿 Biologist • Aspiring 🌺 Designer Researcher at Binomica Labs • Degreeless Heathen • Petunia Breeder • Open Lab Notebook: https://t.co/umYTLluuuwWorking Mass @DSAWorkingMass
5K Followers 2K Following Working class news, analysis, and commentary written by Massachusetts DSA members🌹 DM us pitches and tips 📝 RTs ≠ endorsementsJeannette Tenthorey @JTenthorey
1K Followers 173 Following UCSF Assistant Professor and HHMI Hanna Gray fellow studying host-virus interactions and evolut, with a side of backpacking and some plain old-fashioned nerderyPhilippe Djientcheu @DjientcheuP
25 Followers 118 Following PhD student 🧠 Neuroscientist at University of Yaoundé I, T2D-related brain complications (cognitive and locomotor disorders), Brain-bone crosstalk in T2DGonzalo Moratorio @gonzamoratorio
41K Followers 3K Following Evolutionary&Molecular Virologist doing Science from SouthAmerica🇺🇾/ Featured @Nature's10:Shaping Science 2020/GroupLeader @IPMontevideo /Assoc.Prof @UdelaruyKim Reynolds @kimreynolds_lab
654 Followers 302 Following Asst prof in Systems Biology and Biophysics, UTSW, Dallas. Not the gov of Iowa. Interested in gene-phenotype relationships, protein engineering and synth bio.Michael C. Jewett @MichaelCJewett
7K Followers 483 Following Professor of Bioengineering, Stanford UniversityColin Jackson @Jackson_Lab
2K Followers 920 Following Protein Engineering and Evolution. Views my own.Cori Fain @Cori_Fain
2K Followers 4K Following 👩🏽🔬 @MayoGradSchool | Mom | Scientist 15+ years |🧠 #NativeinSTEM #firstgen #Neuroimmunology #WomenInNeuroIMM #NSPeepsDr. Sabrina Green, Ph.. @MotherOfPhage
13K Followers 8K Following #Phage scientist at @KU_Leuven 🇧🇪 | #Science communicator | Advocate for phage therapy for patientsPatricia L. Clark @ndbiochemist
818 Followers 700 Following NIH Director’s Pioneer Award | Figuring out how proteins fold in the cell | Prof of Biochem & Biophys @NotreDame | Assoc VP @UNDResearch | SciArt, yarn.Tarjani Thaker @tarjanithaker
163 Followers 362 Following Assistant Professor in @Biochem_Chem @uarizona. #StructuralBiology and #MembraneProtein fanatic! Former @JuraLab_UCSF Postdoc, #Vanderbilt PhD. We're #hiring!30-50 Farrell Dobbs @PSolidarity08
2K Followers 2K Following Colombian 🇨🇴 Teamster ✊ Marx was right.arathi @nayerarathi
1 Followers 4 FollowingVignuzziLab @VignuzziLab
16K Followers 9K Following viruses-evolution-Singapore-fitness! @idlabs_astar. #PrideInSTEM 🏳️🌈 #DiversityInSTEM 🇸🇬🇮🇹🇨🇦🇫🇷🇺🇸🇸🇦🇬🇧🇭🇺🇲🇾Michael Poulsen @michaeltpoulsen
2K Followers 3K Following Professor in Evolution of Microbial Symbiosis at the Department of Biology, University of Copenhagen. Follow my group @socsymevo. Views are my own he/him 🏳️🌈Jose Alex Rodrigues, .. @JoseARodrigues8
924 Followers 3K Following PSTDP Intern @KidsAtColumbia, @CheAndamMicro and @Manning_Lab Alum, Microbial Genomics, Eco, Evo, Epi, @A_P_S_A Past Prez. Proud Dog Dad! Views are my own.Craig Kaplan @TriggerLoop
5K Followers 979 Following Professor, Department of Biological Sciences, University of PittsburghQuang Nguyen 🌈💡.. @QNNDuke
1K Followers 5K Following @NDMOxford DPhil| Erasmus Vaccinology MSc| @DukeU BS| @ArtisVentures Fellow, Computational vaccinology enthusiast 👾 SLO CD8 T cell diversityDr. Michael D. L. Joh.. @blacksciblog
15K Followers 5K Following Assoc Prof @ImmunobiologyUA | Metal Meets Microbes | Killin' it with Copper | https://t.co/HqpWlw2ifx #NSURP2024 @NSURPorg https://t.co/y2BGIGFtaOKushol Gupta @GuptaPenn
2K Followers 4K Following Research Assistant Professor of Biochemistry and Biophysics | Director, Johnson Foundation Biophysics and Structural Biology Core Facility | Univ of PA | he/himPhillip McCown @pjlmac
471 Followers 1K Following University of Michigan computational biologist and RNA jock who is working to help end kidney diseaseLu Chen @luchenlab_FCCC
564 Followers 1K Following Assistant Professor https://t.co/C1RcAPDAyY @foxchasecancer @CeiFccc studying RNA biology in diseases; trainings @ScienceStowers and @Stanford.María Angélica Brav.. @MariangeBravo
2K Followers 967 Following HHMI Hanna Gray Fellow at @MCB_Harvard studying chromosome segregation | Incoming Assistant Professor @CornellMBG | PhD @ScienceStowers | she/her | 🇲🇽Krishna Mudumbi @KrishnaMudumbi
1K Followers 1K Following Dad, biophysicist, nerd, political junky | Postdoc @Yale studying membrane protein signaling using #SingleMolecule #Microscopy | @theNCI Early K99 Fellow.Harvard Cryo-EM Cente.. @HC2EM
1K Followers 2K Following Consortium formed by Harvard Medical School, Dana-Farber Cancer Institute, Boston Children’s Hospital, & Massachusetts General Hospital. @harvardmed 🟦☁️ @HC2EMDoug Kojetin @DougKojetin
1K Followers 3K Following Structural biologist & molecular pharmacologist | #nuclearreceptors | #NMR | @VanderbiltU @VUBasicSciences @VandyBiochem @VanderbiltCSBTJ McCorvie (@alloste.. @allostericstate
1K Followers 2K Following Revealing the hidden world of shape shifting enzymes using Cryo-EM. Senior research associate at Newcastle University, UK.Mosasaurus (revived) @mosasaurus27
46 Followers 227 Following Studying biochemistry and immunology. Working in synthetic biology, hope to develop vaccines and therapeutics. I write down my ideas, they’re probably flawed.Ashwin Nair @Ashwin_KNair
143 Followers 152 Following Previously, Biologist@NCBS. Currently, Post-Doc@ NIH. Views are personal. Exploring Viruses.Keith Slotkin @Slotkin_Lab
3K Followers 3K Following Scientist @DanforthCenter & @MizzouBiology studying mobile DNA called Transposable Elements in plant genomes. Father, foodie & political junkie.notslar @notslar
265 Followers 2K Following PhD in something tech, Esq. Paying attention for the next gen.Ryan @Ryan_Gill2
29 Followers 127 Following Cell Imaging and Analysis Specialist at Thermo Fisher ScientificKasper Planeta Kepp @KasperKepp
7K Followers 659 Following Computational biochemistry & biomedicine; protein evolution, disease modeling. Ph.D. Lund; Postdoc Yale & Stanford.Elia Salibi @EliaSalibi
102 Followers 384 Following Engineers cells with chromatin regulators. Currently postdoc at MIT (Del Vecchio). PhD at TU Dortmund University (Mutschler). MSc at University of Pavia (Magni)Frank Santoriello @fsantoriello
3K Followers 1K Following Postdoc with Bonnie Bassler @PrincetonMolBio | @CUAnschutz Micro PhD | Lover of microbes | Fermenter of foods | Occasional maker of art | he/himAdrian Liston @LabListon
10K Followers 5K Following 🇦🇺🇧🇪🇬🇧👨🔬🌈 Professor of Pathology at @CamPathology @Cambridge_Uni. @ImmunolCellBiol Editor-in-Chief. DaddyHeather Snell, PhD @HeatherDSnell
6K Followers 5K Following Neuro. Cerebellum. Assistant Professor @YaleNeuro, @AllenInstitute Next Gen Leader, Board Member of @Tribeswaliga. My words. She/hermarsa @Andromedasoup
298 Followers 71 Following Slightly optimistic as a nondeterministic turing machine operating on a dysfunctional nervous system *Requires a steady diet of synchronicité to thrive. (human)Harmit S. Malik @HarmitMalik
44K Followers 8K Following Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). @HutchBasicSci @fredhutch @HHMINEWS He/himUMass Amherst @UMassAmherst
60K Followers 498 Following #UMassAmherst is the largest public research university in New England distinguished by top-ranked academics, innovative research, and programs.Ivan @chaperones4life
461 Followers 624 Following Chaperones. Guide people. Assemble nucleosomes. Fold proteins. Tweeting as a structural biochemist with a love for chaperones and chromatin. Views are my own.Eli Fritz McDonald @EliFritzMcD
240 Followers 312 Following Vanderbilt PhD Candidate | Chemical Biologist, Structural Biologist, Chemical Engineer | @MeilerLab and @Plate_Lab | membrane proteins, chaperones, drug bindingMona Wu Orr @_pseudo_mona
2K Followers 2K Following Microbiologist studying small proteins. Fermentation enthusiast. Would like to pet your dog. She/Her. Views are my own & do not reflect Amherst College's.carl soderstrom @soderstromcarl9
39 Followers 87 Following Amherst College '24 He/him Biochemistry/Biophysics and French majorIt was a real adventure working on this over the last few years, I'm really happy for it to be out. There's so much we can do now from measuring/engineering CO2/O2 specificity, catalytic rate or even plant rubiscos!
What limits rubisco function? Is it the chemical mechanism? Evolution? In an updated pre-print @prywes et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7)
@Little_Machines @kimreynolds_lab We haven’t diy’ed them - it would be really nice to have multiple chambers tho to do growths in parallel
@Little_Machines @kimreynolds_lab pioreactor.com we’ve played with this a bit @protostasis was fiddling for awhile with them - they are a low cost way to begin to see if it makes sense
Physical protein interactions constrain interface sequence. But what about non-binding "biochemical" interactions in metabolism? We used deep mutational scanning to map sequence constraints for two enzymes that catalyze consecutive metabolic reactions: rdcu.be/dE7xl
A new kind of @ASAPbio_ ? 🤔 ncbi.nlm.nih.gov/gene/50807
We made the cover of @cellsystems! Elementary landscapes for two fitness functions reveal that combining them creates a more rugged landscape. This highlights the demand on a DNA-binding domain to evolve affinity for distinct half-sites @Jackson_Lab tinyurl.com/yc2web9a
Epic thread by @MoezDawood but this has been a long time in the works with @ee_reh_neh (and many others)! tldr There are massive disparities in genomic medicine for non-European ancestry groups. Unbiased saturation mutagenesis can potentially eliminate classification disparities!
Excited to announce our preprint using MAVEs to reduce variant classification disparities in underrepresented populations and demonstrating AI bias in computational predictors for variant classification! (medrxiv.org/content/10.110…) Tweetorial below! (1/25)
How do we interpret molecular mechanisms of protein allostery from deep mut scan experiments? We have built a generalized thermodynamic model to infer and predict how mutations impact inter-and-intradomain allostery. Great collab with Qiang Cui BU @eLife doi.org/10.7554/eLife.…
Spring 🌸 (and labor) is finally in the air! Get together, enjoy the spring weather, and socialize with labor movement folks from across the East Bay at our picnic on 4/28 from 3-6 at Snow Park! We’ll also hear a report back from the Labor Notes Conference in Chicago
Go ahead and read our new microtubule pre-print available on @biorxivpreprint! Congratulations to @Juanmabertoldi1 and everyone who was parte of this study. 🧵available in Juan's post.
Happy to announce that my most recent PhD work from the @NogalesLab @UCBerkeley is out on @biorxivpreprint! We teamed up with @Yildiz_Lab to explore how HURP and Kif18A work together to make sure chromosomes are properly aligned during cell division.🧵⬇️ biorxiv.org/content/10.110…
@Little_Machines Love the lab. Share the science. Hard to explain to people who haven't worked in a lab the rush of encountering a finding/result that is known to no one else - ever. Good luck!
@Little_Machines Apropos of nothing, I followed because your original post tickled my funny bone for some reason. Could be because I legit get to say "There is trouble down at the lab" at least once a month! Congrats on your new laboratory!
@Little_Machines I’ll repost when you make the announcement
@Little_Machines I have no idea what that is, but I do enjoy biochemistry so I’m here for whatever it is you do. 😀👍🧬🧪🥼🔬
Experiment. Educate non-specialists as well as specialists. Repeat.
Thank you all!! Update- I have more than like zero followers now!!
@Little_Machines I’ve been following since before it was cool!