Thomä Lab @LabThoma
We are a structural biology lab located both at EPFL in Lausanne and at the Friedrich Miescher Institute in Basel. thomalab.org Lausanne, Switzerland Joined January 2019-
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🔬 Join us at EPFL's School of Life Sciences as a Staff Scientist Expert in Cryo-EM! Work with cutting-edge facilities, collaborate with top researchers, and drive groundbreaking discoveries in structural biology. Apply now: ch.indeed.com/viewjob?jk=b45… #ScienceJobs #CryoEM #EPFL
📢📢📢 SAVE THE DATE! Join us for the @EMBO Workshop on "Ubiquitin and ubiquitin-like proteins in health and disease", 27th September – 1st October 2024, in Cavtat-Dubrovnik, Croatia. #emboubiquitin For more information and registration: meetings.embo.org/event/24-ubiqu… Please share 🙏
Congratulations Luke!
Hey hey, if you like cell biology, virology, and enjoy Swiss chocolate. Join me at @FMIscience by applying for the lab manager position👇👇😃
Hey hey, if you like cell biology, virology, and enjoy Swiss chocolate. Join me at @FMIscience by applying for the lab manager position👇👇😃
What an unforgettable week of celebrations! 🥳 I am beyond grateful to the @aaas, @ScienceMagazine, @scilifelab, and the Knut and Alice Wallenberg Foundation for your support of early career scientists through the Science & @scilifelabPrize!
Hura!!!
We are pleased to bring you the @CellCellPress paper of #FacesofCell Dr. Jacob Aguirre (@LabThoma), “Orphan quality control shapes network dynamics and gene expression” cell.com/cell/fulltext/…
Congratulations @zkozicka on this amazing accomplishment! We are excited to follow your work on #molecularglues in the next chapter of your career.
Congratulations @zkozicka on this amazing accomplishment! We are excited to follow your work on #molecularglues in the next chapter of your career.
NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! nowak-lab.com
Thrilled to announce the lineup of speakers and open applications for our symposium to mark the opening of @UoDCeTPD! It promises to be a wonderful occasion to celebrate our field. Having so much fun to work in this with @val_spiteri @CharlCrowe @CraigMCrews Brenda and team!
Thrilled to announce the lineup of speakers and open applications for our symposium to mark the opening of @UoDCeTPD! It promises to be a wonderful occasion to celebrate our field. Having so much fun to work in this with @val_spiteri @CharlCrowe @CraigMCrews Brenda and team!
Another exciting position @EPFL in Life Science Engineering, spanning the disciplines of: synthetic, systems and computational biology, cellular and tissue engineering, biomaterials, functional genomics, proteomics and metabolomics! Find the details here: epfl.ch/about/working/…
An excellent perspective on the personalities of #molecularglues, thanks for covering our work @Dereklowe!
An excellent perspective on the personalities of #molecularglues, thanks for covering our work @Dereklowe!
Don’t miss out on attending the Keystone Targeted Protein Degradation and Proximity Therapeutics, January 21-24, 2024 🧬⛷️👩💻 Abstract deadline is October 26. Targeted Protein Degradation lnkd.in/erkd5Yt4 Proximity Based Therapeutics lnkd.in/evkF59ga
Join us tomorrow at 11 am EST for a seminar focusing on UBR5, one of this summer's "hottest" ligases. Featuring speakers @jonathanMtsai, Jacob Aguirre, @KevinGMark, and @DurgaKolla427. Ebert Lab, @LabThoma, @RapeLab …afarbertargetedproteindegradation.org
To bid farewell to Nicolas Thomä and his group, we looked back at @LabThoma's work on ‘molecular glues’, which — by informing the development of molecules that target and destroy disease-causing proteins — may help researchers treat incurable conditions. fmi.ch/news-events/ar…
Thank you @fmi! It has been a pleasure to be part of the institute and we are very grateful for all of the support, from colleagues, friends, coworkers and the great facilities - especially Simone Cavadini @emcccava @georg_kempf and Lukas Kater
Thank you @fmi! It has been a pleasure to be part of the institute and we are very grateful for all of the support, from colleagues, friends, coworkers and the great facilities - especially Simone Cavadini @emcccava @georg_kempf and Lukas Kater
Thanks Jay!
After 17 wonderful years at @FMIscience, the Thomä lab is pleased to announce the start of a new chapter at @EPFL as the Paternot chair in translational oncology. Excited to continue working with current collaborators as well as new colleagues in Lausanne.
After 17 wonderful years at @FMIscience, the Thomä lab is pleased to announce the start of a new chapter at @EPFL as the Paternot chair in translational oncology. Excited to continue working with current collaborators as well as new colleagues in Lausanne.
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Congratulations J. Wade Harper of @harvardmed, newly inducted #NASmember! #NAS161 #biochemistry #cellbiology #microbiology
Master's thesis opportunity at @Empa & @EPFL! Perform high-throughput CO2 electrocatalysis experiments & work with machine learning experts to develop predictive models. Apply for Young Talents Fellowship: polybox.ethz.ch/index.php/s/3A… by 30/04/24. #MScThesis @NCCR_Catalysis
Next stop MSc thesis? 📣 Apply now for an #NCCRCatalysis Young Talents Fellowship to conduct your funded Master’s thesis project on sustainable chemistry & catalysis 🌱🧪🌍 within our member labs in 🇨🇭! ⏰ 30 April 2024 📑 More info bit.ly/2024YoungTalen… 🔁 Appreciated 🫶🏻
...and here is the correct link: uu.varbi.com/en/what:job/jo…
What a treat!!! Gwenn Hansen, CSO of @Nurix_Tx, teaching the #MolecularTherapeutics students of MCB220 at @UCBerkeley @berkeleyMCB the ins and outs of drug discovery - from finding your molecule to seeing it help patients in the clinic!
Great to see this story out - congrats to the team 🎉
Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome…
Farewell old FMI Building - we are moving for real to the other side of the Rhine #FMIMove
Thrilled to announce the Gallini lab (gallinilab.com) will open the door this October @epflSV. Excited to start this new chapter and eager to contribute to the stem cell and cancer biology fields with exciting new discoveries.
Happy International Women’s Day! Thankful to have the privilege to work with this group of amazing women in my lab in the past 4 years. 💐🎉👩🏻🔬🧑🔬@ZalaSekne @HochheiserInga @_helenyan_ (with picture this time)
Prof. Radosław P. Nowak hat die neue #Professur für „Immune Engineering and Drug Discovery“ am Institut für #Strukturbiologie des Universitätsklinikums #Bonn (UKB) angetreten. #ukbonn ukbnewsroom.de/experte-fuer-g…
Congratulations to Dr @kasim_waraich on a successful thesis defence. It was never in doubt. Thanks also to Ed Morris and @yorgomodis for taking the time to read and examine Kasim's thesis.
Don’t think I’ve ever seen an E3-Ubi complex primed to ligate to its target bound to a nucleosome before 🤯
🎉 We are thrilled to announce the release of the latest structure of the #cGAS complex in PDB as rcsb.org/structure/8OL1🌐✨Stay tuned for the full story in our upcoming paper, where we unveil the secrets behind cGAS transportation and its ultimate destiny. #Immunity
🎉 We are thrilled to announce the release of the latest structure of the #cGAS complex in PDB as rcsb.org/structure/8OL1🌐✨Stay tuned for the full story in our upcoming paper, where we unveil the secrets behind cGAS transportation and its ultimate destiny. #Immunity
Come join us at @HC2EM to do cutting-edge cryo-EM! We have a fantastic setup, amazing colleagues and a great research environment.
Roses are red Violets are blue If you love Cryogenic Electron Microscopy This job ad is for you: jobs.brassring.com/1033/ASP/TG/ci…
EPFL startups raised CHF 470 million in 2023 – a record figure if we exclude 2021, an exceptional year with three IPOs. A total of 23 startups were created in 2023, and over a third of them by women. go.epfl.ch/904c86
Proud to share our new paper with the Cramer lab (@mpgpresident) in @NatureSMB! Led by the wonderful @KokicGoran and @George_Yakoub_M with great collaborators. Elongation factor ELOF1 stably positions repair proteins on RNA polymerase II. nature.com/articles/s4159…
Woohoo! Really excited to present our discovery that stress response silencing is an active and regulated process that is tightly linked to neurodegenerative disease! @Nature @berkeleyMCB @UCBerkeley #MolecularTherapeutics nature.com/articles/s4158…
New from our amazing lab neighbours 🤩🤩🤩
Proud to share our latest work by the talented duo @AutomneNine and @ZalaSekne on the 2.7 Å structure of telomerase H/ACA RNP with new insights into disease mutations and pseudouridylation. Assisted by the newest lab member during revision. rdcu.be/dwUyY
👏📷Congrats to Andrei Zhauniarovich, winner of the Best Master Thesis Award 2024 @SNE_ChemBio for his work: “Exploring the Landscape of Tubulin Post-Translational Modifications: Interplay Between α-Tubulin Polyglutamylation and Detyrosination” @sciences_UNIGE @EPFL_en #chembio
I'm happy if somewhat shy to share my review on protein PTMs: the history of PTM research, key paradigms, chemical & mechanistic principles, and hypotheses re PTM evolution. I thought a unified narrative like this might be interesting to some readers. onlinelibrary.wiley.com/doi/full/10.10…
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