An alternative to the “no germs” theory of ⬆️ respiratory infections: Over 80% of the population has now been exposed to Covid and it’s been shown you can be immunosuppressed months after infection. So our increased infection rate, may be due to our increased infection rate. 🤯
What’s the data in support of this theory? Cohorts of children born both before AND after peak pandemic shutdowns have been observed to have higher RSV admissions than those born during shutdowns. I.e. the risk correlate wasn’t lack of exposure to RSV, but exposure to Covid. 🤔
@JeromeAdamsMD Definitely. @fitterhappierAJ has been telling us all along.
@JeromeAdamsMD Keep in mind the data doesn't say the length of immunosuppression is just months(7 to 8 months on two recent studies). That was the length of follow up. With deliberate and forced reinfections we should assume this to be permanent. We have hypoimmunity at the population level.
@JeromeAdamsMD This, my friends, is how conspiracy theories get legs.
@JeromeAdamsMD Why would Covid have this effect yet not other Coronavirus infections? I get the effect on the elderly that get severe disease, immune storm etc often but the vast majority of young kids have exactly the same course as other Coronaviruses.
@JeromeAdamsMD Even if kids were exposed pre Covid, stopping respiratory disease exposures for 2 years could be creating immune debt as we often don’t keep high neutralizing Abs for resp illnesses (as we’ve seen with Covid reinfections).
@JeromeAdamsMD Pathoimmunology 101: anergy. Most ignore immunocompromise due to infections, because it is so prevalent: opportunistic secondary infxns (HSV). The shock-bow effect that leads to anergy is part of the reason we have evolutionarily redundant systems. See eg: ncbi.nlm.nih.gov/pmc/articles/P…