Justin Sharim MD @JSharimMD
Cardiologist. App creator, @CardiacTrials Los Angeles, CA Joined September 2023-
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Following225
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HFpEF vs HFmrEF management 🏥 via #esc2023 #EBM 🔑 Clinical Trials: 🔹DELIVER (2022) and EMPEROR-Preserved (2021): SGLT2i in EF>40% 🔹PARAGON-HF (2019): ARNI vs ARB in EF>45% 🔹TOPCAT (2014): MRA in EF>45% 🔹CHARM-Preserved (2003): ARB in EF>40% App 🔗 apps.apple.com/us/app/cardiac…
Timeline of completed & ongoing LDL cholesterol lowering CV outcomes trials 📚 The data is overwhelming #Cardiotwitter #MedTwitter #ACC2024 #FOAMed #MedEd #cholesterol @Drlipid @ProfSNicholls
Life update: proud to say that I’ll be returning to my med school alma mater as a faculty member, accepting a position as attending cardiologist at UCLA @UCLAHealth Grateful for my mentors, especially Drs. Matthew Budoff @BudoffMd, Quang Bui, Priya Pillutla, and Sam Daneshvar
Ways to diagnose HFpEF ? 🫀 H2FPEF 🫀 HFA-PEFF 🔑 Both are useful, but neither is perfect #MedTwitter #CardioTwitter #ACC24
Which came first — the PVC or the cardiomyopathy? 🐓🥚 PVC-mediated cardiomyopathy vs cardiomyopathy-mediated PVCs 🤜🤛 JACC, 2019 ♥️
To see is to know
ASE Valvular Stenosis and Regurgitation Guidelines 📚 — summarized in just two infographics (for all 4 valves) #cardiology #echofirst #cardioX
🔑 2024 PRACTICE-CHANGING CLINICAL TRIALS this past week #recap ~~ a thread 🧵 ~~ 👇
There are some drugs that got a positive result with a composite endpoint. Digoxin would have met this criteria. And in a subgroup analysis you would see that the drive was reduced heart failure hospitalisation and not CV death. 🤔 You know what I mean?
There are some drugs that got a positive result with a composite endpoint. Digoxin would have met this criteria. And in a subgroup analysis you would see that the drive was reduced heart failure hospitalisation and not CV death. 🤔 You know what I mean?
In whom & why do I use Semaglutide? 💉T2DM 👉🏼 SUSTAIN-1 ⬇️ HBA1c 💉T2DM 👉🏼 SUSTAIN-6 ⬇️ MACE 💉Obs+HFpEF 👉🏼 STEP HFpEF ⬆️ QOL 💉Obesity+CVD 👉🏼 SELECT ⬇️ MACE 💉T2DM+CKD 👉🏼 FLOW* ⁉️ * Trial stopped early due to evidence of renal protection 🔗 SUSTAIN-1…
Non-statin LDL lowering therapies and % reduction via #ACC24 @CardiacTrials
Should statins be made available over the counter? A patient self-selection win
Should statins be made available over the counter? A patient self-selection win
#ACC24 LBT: DanGer Shock - 355 Danish/German/UK (79% male) patients post-AMI in cardiogenic shock were randomized to ImpellaCP+standard care vs. standard care only - Significant ⬇️ 1° endpt of death from any cause at 180d - But ⬆️ risk of bldg, RRT, sepsis @CardiacTrials
#ACC24 Late Breaking Trial: REDUCE-AMI - Approx 5000 patients who were post MI and had LVEF >= 50% were randomized to beta blocker vs. no blocker - Median follow-up of 3.5 years - No difference in primary endpoint of all-cause death or MI, or secondary endpoints! @CardiacTrials
#ACC24 ~~ Ultimate-DAPT Trial 🔑 In patients receiving PCI for ACS, Ticagrelor monotherapy after only 1 month of DAPT decreased bleeding WITHOUT a change in ischemic events when compared to traditional year-long DAPT 📸 via @JayShah_MD
PREVENT Trial #ACC2024 Preventative PCI + OMT to OMT alone for the treatment of non-flow limiting vulnerable plaques. Preventative PCI reduced composite risk of cardiac mortality, target vessel MI, ischemia-driven TVR, or hospitalization for angina at 2 years. @CardiacTrials
ULTIMATE DAPT via #ACC24! 🫀 Ticagrelor monotherapy after 1 month of DAPT post ACS w/ PCI non-inferior in regards to major adverse cardiac/cerebrovascular events w/ significant ⬇️⬇️⬇️ in major bleeding 🩸 Maybe time for guidelines to change regarding DAPT! @CardiacTrials
🔥Highlights from the Late breaking SMART trial studying Self-Expanding vs. Balloon-Expandable TAVR in patients with small aortic annuli - that enrolled 75% women! 🔥 #ACC24 @CardiacTrials
Our new paper on colchicine and plaque just published authors.elsevier.com/a/1itao7X7QCZC…
Gina Horton @HortonGina90532
0 Followers 80 Following
Alana Regen @AlanaRegen51033
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Andrew @DrewLinMD
94 Followers 132 Following Cardiology fellow @UCSDCardFellows. Interest in heart failure + electrophysiology. @ucsdim 2017. @IUSM 2013.
Alice @davis_erik7328
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R @nanziKSR
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Jonathan Brisbon @medbrisbon
2K Followers 3K Following Class of 2025 @RWJMS I Cancer Survivor I Mental Health Advocate I Masters of Biomedical Sciences from NJMS I Urology Match 2025
Alexander Phan, MD, M.. @alexanderphanmd
99 Followers 261 Following Chief Resident, powerlifter, speedcuber, pianist. Soon-to-be pulm/crit fellow @LLUHealth. Interests: IP, POCUS, and MedEd. @JohnsHopkins and @Georgetown grad.
Nikhilesh Bhatt, MD @N_Bhatt_
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Dana Momani @dana75173
254 Followers 888 Following MS4 @JUSTEDUJO • Student Ambassador @AMBOSSmed • Passionate about health equity and peer mentorship • 🏊♀️👩🍳📝
Manish Motwani @Doc_Tiger
3K Followers 4K Following Cardiologist. Doctor. Pioneer. Author. Philanthropist. Geek. Healer. Comedian. Joker. Class act. Survivor. Networker. NBD. Multimodality CVImaging.
Richard Ferraro @RichardAFerraro
3K Followers 662 Following Cardiology Fellow @hopkinsheart. Social Media Editor @JACCJournals. Contributor @cardionerds. Views my own, not medical advice
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Jerrie Mender @jerrie71149
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Dewi@1985 @Dewi62178205
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1ff4i2mgi259mu @102nqnwx2d9xt
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RB&HH Education @RBHHEducation
882 Followers 2K Following Your source of the latest information on education and training from the world’s leading experts in heart and lung care at Royal Brompton & Harefield hospitals.
Sophia_Onasy🇺🇸 @Sophia_Onasy
1K Followers 2K Following Love work, love food, have a sense of accomplishment, #patriotic🇺🇸...my pet...I stand my ground💪🏻
Mindy Ciskowski @MinCiskows
37 Followers 5K Following
Tyler Millhouse @Tmillhouse12
134 Followers 58 Following
Norman manuel Luna um.. @norman_umana
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umer bin shabir @Ubs__ubs
490 Followers 1K Following
sejal kotwani @KotwaniSejal
328 Followers 2K Following
Abdelhamid Hamdy @abdelhamed012
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Hamed @ABOKHADIGA20
5 Followers 32 Following
Kreps Law Firm @KrepsLawFirm_
4K Followers 4K Following Kreps Law Firm, L.L.C. Statewide Alabama Defense Attorneys - DUI, Traffic, Drug Crimes and Professional Board Defense. Call us TODAY! (866) 348-2889
Austin Saugstad @Saug13
574 Followers 555 Following Creighton University IM resident //////////////////// Follower of Christ
Laraine Bold @LaraiBol
51 Followers 5K Following
Katharine Yang @thekatyang
254 Followers 856 Following Cardiology fellow @ Harbor-UCLA, IM Residency @ LAC-USC, Baylor CoM & Rice alum 🦉
Michael DiCaro MD @MichaelDicaro
52 Followers 37 Following PGY2 Internal Medicine Resident at @UNLV | @cardiactrials Ambassador
Bobbye Discon @DiscBobby
73 Followers 5K Following
Dr. Shovan Kumar @ShovanKumar19
88 Followers 990 Following MD in Medicine Cardiology Resident at MKCG MEDICAL COLLEGE AND HOSPITAL
Colby Jordan @Colby_Jordan9
5 Followers 53 Following
Simon Manjooran @ManjooranS63995
0 Followers 27 Following
Rabbi Linda Goldstein.. @realrabbilinda
10K Followers 483 Following Chief Rabbi of #Gaza. #BDS #FreePalestine. I Stand with #Iran. #Trans Rights are Human Rights. Nude Yogi. I/P Commentary.
Talia Khan @TaliaKhan_MIT
4K Followers 119 Following MIT Graduate student in Mechanical Engineering ⚙️ | MIT Israel Alliance President 💙 | Fulbright Brazil Alumna 🌴
Andrew @DrewLinMD
94 Followers 132 Following Cardiology fellow @UCSDCardFellows. Interest in heart failure + electrophysiology. @ucsdim 2017. @IUSM 2013.
UCLA Health @UCLAHealth
46K Followers 4K Following Ranked as one of America's top hospitals and providing the best care at more than 270 locations throughout So Cal. Official UCLA Health account. #BestHospitals
Harbor-UCLA Medical C.. @HarborUCLA
1K Followers 168 Following Official Twitter account for Harbor-UCLA Medical Center
David Geffen School o.. @dgsomucla
6K Followers 1K Following Delivering leading-edge research, education, patient care, and community engagement. #DGSOMUCLA
Manish Motwani @Doc_Tiger
3K Followers 4K Following Cardiologist. Doctor. Pioneer. Author. Philanthropist. Geek. Healer. Comedian. Joker. Class act. Survivor. Networker. NBD. Multimodality CVImaging.
Ritchie Torres @RitchieTorres
193K Followers 9K Following A personal account in which I speak for myself rather than for the federal government. For official announcements, please follow @RepRitchie.
Shai Davidai @ShaiDavidai
94K Followers 1K Following Jewish Israeli. Father. Partner. Zionist. Assistant Professor @Columbia_Biz
Elica Le Bon الیک.. @elicalebon
81K Followers 306 Following Daughter of Iran // Attorney, activist, artist, and other such labels that belie the illimitable dimensions of human existence
Filippo Cademartiri @FCademartiri
2K Followers 180 Following The Art of Medicine & Imaging. Prevent diseases is my objective. HighTech/Clinical Rad. Photon Counting CT, #CCT, #CMR #PCCT #Radiology #imaging. @FTGM/CNR
UC San Diego Cardiolo.. @UCSDCardiology
524 Followers 129 Following Official Twitter account for the Division of Cardiovascular Medicine at UC San Diego School of Medicine
Katharine Yang @thekatyang
254 Followers 856 Following Cardiology fellow @ Harbor-UCLA, IM Residency @ LAC-USC, Baylor CoM & Rice alum 🦉
Alice Benedetti @AliceBen_90
342 Followers 355 Following MD | Interventional Cardiology Fellow | ZNA Middelheim Hospital 🇧🇪 | Cardiology @UniPadova 🇮🇹
Michael DiCaro MD @MichaelDicaro
52 Followers 37 Following PGY2 Internal Medicine Resident at @UNLV | @cardiactrials Ambassador
David Harmon MD @davidharmonMD
2K Followers 2K Following Cardiology Fellow @MayoClinicCV via @MayoMN_IMRES | Alum @TAMUmedicine @WheatonCollege | Live Tweeting🫀education and AI research | Tweets = mine.
Pedram Amini @pedramamini
7K Followers 809 Following CTO at @InQuest. Previously founded @theZDI. Investor, advisor, hacker. NYC born, Austin transplant. I tweet about infosec and general nerdery.
Jonathan Davis, MD, M.. @JonathanDavisHF
3K Followers 628 Following Director @sfhealthnetwork HF Program Zuckerberg SF General Hospital @zsfgcare @ucsfcardiology. New Dad x2! Alum @WUSTLmed⬅️ @UCSFmedicine⬅️ @cornell he/his/him
Robert Mentz, MD @robmentz
12K Followers 9K Following Editor-in-Chief @JCardFail | Chief of the HF Section @DukeHealth | Trialist @DCRInews | Father of 3
Siyab Panhwar, MD @DrSiyabMD
9K Followers 2K Following Interventional cardiologist. Country doc. Passionate abt heart disease prevention/education on social media (600k TikTok followers). Views own. 🇵🇰 🇶🇦 🇺🇸
Arjun Khadilkar, MD @akhadilkarMD
14K Followers 455 Following Cardiology fellow @IUcardsfellows 🫀| Interested in Prevention and Medical Education | Via @USFIMres @UToledoMed @cwru | Husband to @salonijairdn|
Sam Srivastava @samsrivastava77
276 Followers 188 Following Cardiologist • Multi-modality Cardiovascular imaging • Musician
Andrew J Sauer MD @AndrewJSauer
17K Followers 2K Following Cardiologist @MidAmericaHeart, building programs to implement therapies, advance discovery, and foster innovation for patients suffering from heart failure.
Allan L. Klein @AllanLKleinMD1
4K Followers 254 Following @ClevelandClinic Cardiologist, Director of Pericardial Center & Prof of Medicine | Past President ASE | President Elect NBE /Opinions expressed here are my own
Karan Desai MD FACC @karanpdesai
2K Followers 958 Following Asst Professor @hopkinsheart @hopkinsmedicine @jhhecho. Asst Program Director and proud alum of @bayviewmedicine IM.
Pasquale Paolisso @P_Paolisso
3K Followers 4K Following MD, PhD, FESC | Cardiovascular Center Aalst, Belgium 🇧🇪 | University Cardiology, IRCCS Galeazzi-Sant'Ambrogio Hospital, Milan, Italy 🇮🇹
Marat Fudim, MD MHS @FudimMarat
4K Followers 980 Following Duke Cardiology, 🇺🇦+🇩🇪+🇺🇸, #HeartFailure. Views expressed are my own and do not reflect the views or opinions of my employer.
Danielle Belardo, MD @DBelardoMD
77K Followers 3K Following Cardiologist obsessed with prevention & nutrition science
Jeff Hsu, MD, PhD @JeffHsuMD
3K Followers 936 Following Adv HF/Tx Cardiologist @UCLAHealth @LosAngelesVA | SoMe Editor #JACCBTS | Alum: @MIT @dgsomUCLA @UCSF | #SportsCardio #Mechanobiology #Calcification #LongCOVID
Ali Nsair, MD @AliNsairMD
2K Followers 921 Following Medical Director, Heart Transplantation and Mechanical Circulatory Support, UCLA. Interventional Cardiology. Director, UCLA Sports Cardiology.
Greg Marcus @gregorymmarcus
2K Followers 464 Following Professor of Medicine, Cardiac EP & Investigator at UCSF, father, husband, interested in promoting science and avoiding dogma to discover and disseminate truth
Amy West Pollak MD @DrAmyPollak
1K Followers 279 Following Heart health advocate, cardiologist at Mayo Clinic. Interests: PAD, women’s heart health, echo/cardiac MRI. Mom of curious kids, dog-lover. Opinions are my own.
Jeffrey Geske, MD @jeffreygeske
3K Followers 460 Following @MayoClinicCV cardiologist. #cvHCM, #cvVHD, #echofirst focus. #JACCIMG #SoMe editor, #EHJ editor. Professor of Med. #MayoCVBR co-director. Tweets=my own.
mandeep singh @mandeep_mayo
6K Followers 69 Following Interventional cardiologist with passion for aging research. Proud dad and husband. All opinions my own.
UCLA Biodesign @UCLABiodesign
306 Followers 213 Following UCLA Biodesign works with industry partners and the medical community to advance solutions that deliver improved value and outcomes to patients worldwide.
Andrew Lin @DrAndrewLin
1K Followers 853 Following Cardiologist & Postdoctoral Researcher trying to better understand coronary plaque through imaging, AI & data science | @CedarsSinai @BartsHospital @MonashHeart
Prashanth Venkatesh @PVenkateshMD
402 Followers 226 Following Adult Congenital cardiologist @CedarsSinaiMed
Darcy Wooten she/her @Darcy_ID_doc
6K Followers 2K Following Mom, Wife, Professor, ID/HIV doc, ID fellowship PD for @ucsd_idfellows, FIDSA @IDSAinfo, medical education enthusiast.
Ankeet S. Bhatt, MD, .. @ankeetbhatt
2K Followers 2K Following Crit. Care Cardiologist @kpnorcal @kpdor | Adjunct Prof. @StanfordMed | Prior @MassGenBrigham @IMresidencyDuke | Editor ImpSci @JCardFail | Tweets≠endorsement
Jonathan Hsu, MD @JonHsuMD
4K Followers 5K Following Heart rhythm cardiology doc (Electrophysiology/EP) and Researcher http://t.co/zWzFMTg1Gs at University of California, San Diego (UCSD- http://t.co/ykKkYsny1f)
Vas Panoulas @VPanoulas
2K Followers 163 Following Consultant Interventional Cardiologist at Harefield Hospital , Royal Brompton and Harefield hospitals, Guys and St Thomas' NHS Foundation Trust
Journal of Cardiac Fa.. @JCardFail
8K Followers 261 Following Original peer-reviewed research & reviews #HeartSuccess @HFSA @JHeartFailureS @ElsevierConnect EIC: @robmentz; DE: @dranulala YouTube: https://t.co/CZK2fadx45
Khurram Nasir @khurramn1
7K Followers 3K Following Husband, Father/ Preventive Cardiologist/Health Policy/ Social Justice & Health Equity/Big Data Applications
Marc Dewey @ProfDewey
958 Followers 635 Following Seeing through the human body as Heisenberg Professor of Radiology @ChariteBerlin • Publications @myesr • PI of the DISCHARGE trial • cv on website
Leila Haghighat, MD M.. @LeilaHaghighat
485 Followers 254 Following Structural echocardiography fellow @UCSFCardiology via @YaleIMed @UCSDMedSchool @Cambridge_Uni | Medical journalism
Daniel Pita, MD @danpita
1K Followers 1K Following Cardiologist🫀| #echofirst | @pulsarmanaus | Brazilian Society of Cardiology | Sharing health information🔊 | Living in Amazon Rain Forest | 🇧🇷
Timothy Fernandes, MD.. @DrTimFernandes
586 Followers 565 Following Pulmonary and Critical Care Physician. Director of Comprehensive Pulmonary Embolism Care @UCSDHealth. #PE, #CTEPH, and #PAH. @Browns & @Padres fan. @UCSDPCCM
Laith Alshawabkeh, MD.. @laithalsh
886 Followers 373 Following Director, Adult Congenital Heart Disease Program. @ucsd. Patient advocate. Personal views, not medical advice. RT are not endorsement.
Patrick Zakka, MD @PatrickZakka
2K Followers 386 Following UCLA Cardiology Chief Fellow @uclacvfellows. Emory Internal Medicine/Chief Resident @emoryimchiefs. AUB Medicine. Cardionerds Faculty @cardionerds.
Richard Ferraro @RichardAFerraro
3K Followers 662 Following Cardiology Fellow @hopkinsheart. Social Media Editor @JACCJournals. Contributor @cardionerds. Views my own, not medical adviceThe results of this trial were contemporarily corroborated by the ISCHEMIA Trial, published over a decade later
Improving mortality in coronary artery disease with PCI? This landmark trial was one of the first to suggest that in the absence of acute coronary syndrome, PCI improves symptoms alone — WITHOUT mortality benefit. COURAGE Trial, NEJM 2007 ♥️
So much for “peaceful protests” at Columbia University. Violence is not a bug but a feature of the pro-Hamas encampment movement, which has a deep rot of Anti-Americanism and AntiSemitism at its core.
I love this kid. He’s my new hero.
“Can I please go to class?” “We are UCLA students… I have my ID right here… you’re blocking me… my class is right there …will you let me in? Will you move?” (This morning) @UCLAchancellor why aren’t you protecting your students?!
HFpEF vs HFmrEF management 🏥 via #esc2023 #EBM 🔑 Clinical Trials: 🔹DELIVER (2022) and EMPEROR-Preserved (2021): SGLT2i in EF>40% 🔹PARAGON-HF (2019): ARNI vs ARB in EF>45% 🔹TOPCAT (2014): MRA in EF>45% 🔹CHARM-Preserved (2003): ARB in EF>40% App 🔗 apps.apple.com/us/app/cardiac…
MitraClip for mitral regurgitation? This landmark trial showed benefit in functional MR. Functional MR = MR not caused by a primary valvular pathology, but from a secondary cause (eg from papillary muscle tethering or annular dilation in HFrEF). COAPT Trial, NEJM 2018 ♥️
New LAC classification based on #3DEcho #TruVue @Philips as reliable as #Yessct Look at bend angle 📐 low risk morphology acute bend < 90° in proximal or middle part of dominant lobe 🐓wing can be low or high risk Windsock,cactus,cauliflower high risk bit.ly/3LHD9H
This should be done on every campus @persianjewess in every shopping mall, across all of America!
An anonymous group has funded and constructed a giant screen with loudspeakers outside the @UCLA Pro-Hamas Encampments showing footage of the October 7 Massacre on loop. Bravo to these geniuses. #StandWithIsrael
Lol @edenyadegar I’m flattered 🤣 These people need to get off the internet and start studying 📚
Congrats @TaliaKhan_MIT for making it on #Columbia sidechat - a cesspool of uninformed, antisemitic, anonymous keyboard warriors. I also worry for your well-being - because you’re surrounded by Hamas apologists and ignorant sheep at @MIT
Right now, Jews and Israelis have come into the anti-Israel encampment at @MIT . We brought some food including fresh Israeli watermelon to share with everyone and are singing songs of peace! ✌️ ☮️ 🕊️
An anonymous group has funded and constructed a giant screen with loudspeakers outside the @UCLA Pro-Hamas Encampments showing footage of the October 7 Massacre on loop. Bravo to these geniuses. #StandWithIsrael
A few thoughts on the @UCLA solidarity rally today. 1- We Jews have never been more united. One family. One destiny. We are alive and here to stay. 2- We Jews no matter where we live stand solidly with Israel. 3- We are truly blessed. Although at times it feels like the world is…
@drhungo @Drlipid @ProfSNicholls Nexlitol/Nexlizet uptake must be abysmal. Insurance coverage in the US is practically non-existent.
@RichardAFerraro Endocarditis in the most common presentation of chronic Q fever
Timeline of completed & ongoing LDL cholesterol lowering CV outcomes trials 📚 The data is overwhelming #Cardiotwitter #MedTwitter #ACC2024 #FOAMed #MedEd #cholesterol @Drlipid @ProfSNicholls
A starter breakdown for CABG vs PCI 🤜🤛 🔑 points: 1️⃣ PCI in stable CAD relieves symptoms, but does not improve survival or reduce risk of MI 2️⃣ CABG in stable CAD can improve survival and reduce risk of MI, but is dependent on the severity of CAD, EF and presence of diabetes
CABG vs PCI for multivessel CAD? We must be cognizant of when CABG may improve outcomes over PCI. A nuanced topic with several trials (🔑: BARI-2D, FREEDOM, BEST, EXCEL). Calculating a SYNTAX score stratifies patients by complexity multivessel disease. SYNTAX Trial, NEJM 2009 ♥️
After seeing everything on the news, I decided to go and see for myself what is happening at UCLA. I went in with the intention of having honest conversations to try and truly understand each others pain and suffering . However, no one would speak to me . The only thing they…
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