GiusTo Lab @GiusToLab
Assistant Professor of Neurology @ColumbiaMed #PopulationGenetics #Epidemiology #Neuroscience #Alzheimer #ENDALZ 🏳️🌈 neurology.columbia.edu/research/resea… New York, NY Joined October 2021-
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Check out our lab's latest software! 𝗦𝗔𝗚𝗔 runs 𝗴𝗲𝗻𝗼𝗺𝗲𝘄𝗶𝗱𝗲 𝗮𝘀𝘀𝗼𝗰𝗶𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗮𝗹𝘆𝘀𝗲𝘀 with a simple one-line command! Anyone can access complex genetic analyses 🙌 [developed by the talented Basilio Cieza] 📌biorxiv.org/content/10.110…
GiusTo Lab retweeted
Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!
GiusTo Lab retweeted
Presenting my preliminary results of APOE e4 and Ptau 217 over cognition in quechua and aymara population from GAPP study at #AAIC25 in Toronto. Thanks to @GiusToLab, @NiltonCustodio8 @marciosotoanari
GiusTo Lab retweeted
How does APOE status impact AD risk in Hispanics/Latinos? Research in A&D report APOE ε4 shows a heterogeneous effect on ADRD risk across Hispanic/Latino populations, with the strongest associations in Peruvians/Bolivians #AlzResearch alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
GiusTo Lab retweeted
What does heritability mean as measured multiple ways and what does it mean for our understanding of Alzheimer's? Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review medrxiv.org/content/10.110…
Took a minute (4+ years😅), but we made it! We studied the heterogeneity of APOE and Alzheimer's Disease risk using the largest collection of Hispanic/Latino studies - an amazing collective effort🎉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
v nice thread
I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A 🧵:
Congrats to our star clinical coordinator Jennifer Ortega Morales - she matched yesterday for the Internal Medicine Residency Program! #proudPI
a great collaboration with @NiltonCustodio8 @RosaMontesino18 @marciosotoanari
Finally out our paper on ptau217 and AD in Peruvian populations! A huge effort for the GAPP study, an exceptional cohort of participants from Lima, Arequipa and Puno with deep phenotyping, genetics, plasma and serum available for the scientific community! alzres.biomedcentral.com/articles/10.11…
Closing day at the Brain Ageing and Dementia in LMICs 2024 conference in Nairobi, Kenya 🇰🇪 Dr. @pericakvance taking the stage to present our @NIHAging funded DAWN study for which we have been recruiting thousands of seniors in US and Africa thedawnstudy.com
see you in Vienna! #ENDALZ 🗓️program here: adpd.kenes.com/scientific-pro…
come work with us! #HiringNow #postdoc #postdocappreciationweek #columbia #genetics #ENDALZ #Neuroscience ✏️linkedin.com/jobs/view/4032…
We now have a zebrafish model 🐟 to better dissect the genetics underpinning Fetal Alcohol Spectrum Disorders #FASD - thanks to @CaKizil @gaattagca @NIAAAnews preprint here 👇🏼 biorxiv.org/content/10.110…
A new project from our lab! Fascinating #admixture study on this underrepresented South African population and the risk profile for Fetal alcohol spectrum disorders #FASD. 1% to 5% of U.S. first graders have FASD! @NIAAAnews medrxiv.org/content/10.110…
Check out our poster #338 showing the performance of ptau-217 for #Alzheimer in a large South American cohort #AAIC2024 #biomarkers
Living our best life with AAIC boxed lunch 😂
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