Enzyme Overflow @EnzymeOverflow
Questions and Answers for Science Startups. Powered by @axialxyz reddit.com/r/EnzymeOverfl… Joined March 2022-
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What’s the best & lowest cost way for a startup to file patent?
Which biobanks are the easiest to work with?
Which companies are developing oral biologics?
What online tools exist to find antibody binders (high & low) from a list of sequences?
Small molecule modulators of IL-17 Inventors: Kevin Neil Dack, Xifu Liang, Mogens Larsen, Mark Andrews, Alan Stuart Jessiman, Mia Nørreskov Burhardt, Patrick Stephen Johnson, Peter Andersen, Lars Jørgensen Current Assignee: Leo Pharma A/S
Actio Biosciences raised $55M co-led by Canaan Partners & DROIA Ventures. To advance their pipeline of drug candidates, with the idea to bridge from rare diseases to more common ones.
Walgreen's and Pearl Health announced a partnership to connect the former's capabilities in prescriptions & diagnostics to Pearl's value-based care product offering
Glyphic Biotechnologies @GlyphicBio, founded in 2021, is building a protein sequencing platform to discover & measure proteoforms. Which are a specific molecular form of a protein encoded by gene. Arising from SNPs/CNVs, alternative splicing, and/or PTMs
Self-Inactivating Targeted DNA Nucleases For Gene Therapy invented by David Schaffer …chtransfer.universityofcalifornia.edu/NCD/25333.html
Worth a Read: 'Biotech Models: Virtual Reality vs Virtual Mythology' lifescivc.com/2011/11/virtua…
Are there any good discount codes for biotech reagents/services?
Compromised antigen binding and signaling interfere with bispecific CD19 and CD79a chimeric antigen receptor function Develops bispecific CAR-T cells that target CD19 & CD79a or CD79b. These CAR T cells were designed to overcome the limitations of single-antigen targeting
SIM-PAL: proteome wide identification of small molecule binding sites invented by Christina Woo otd.harvard.edu/explore-innova… Applications: map out a protein/small molecule interactome in a cell versus in vitro
PipeBio @pipe_bio is a cloud-based bioinformatics platform for biologics discovery. It allows wet lab scientists to easily analyze antibody and peptide sequences with functional assay data, and bioinformaticians to deploy their own code and run workflows
Worth a Read: 'Large Language Models in Molecular Biology' towardsdatascience.com/large-language…
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells led by Yogesh Goyal @yogeshgoyallab from the Arjun Raj @arjunrajlab lab
HyTEC: Hybrid Tissue Engineering Construct invented by Seyedsina Moeinzadeh & Peter Yunzhi Yang techfinder.stanford.edu/technology/hyt…
MicroRNA, autoantibody and protein markers for diagnosis of neuronal injury Inventors: Kevin Wang, Zhiqun Zhang, Ming-Cheng Liu, Ronald Hayes, Jitendra Dave Current Assignee: Banyan Biomarkers, US Army
How are DNA-encoded libraries created? DNA-encoded libraries (DELs) are created by covalently attaching a unique DNA barcode to each compound in a library. Which is then incubated with the target protein, and the bound compounds are eluted and amplified.
Raji Shyam PhD (she/h.. @ShyamRaji
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64K Followers 58K Following ㈱ウィズコーポレーション代表取締役。当社は、清須市・あま市をはじめ愛知県西尾張地域をメイン商圏とする不動産会社です。私自身は、明るく、元気で、お馬鹿なキャラクター。堅苦しいことは好みません。目指すは「日本一楽しい不動産会社」。“利他の心”をベースに社員一丸、必ず成し遂げてやります! 学習院大学経済学部卒。盛和塾卒塾。Rylan Drake @rylan_drak83826
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39K Followers 38K Following مرحبًا👋 بك في أكـاديمية النـوابـغ ✍️ حيث يتم تقديم خدمات احترافية في مجال إعداد الأبحاث العلمية، رسائل الماجستير و الدكتوراه، ومشاريع التخرج والأبحاث الجامعيةHeinlein Society @HeinleinSociety
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41 Followers 162 FollowingHeidi Anderson @HeidiAnder87400
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398 Followers 3K FollowingGloria @white_gloria81
159 Followers 3K FollowingMaaHir Afridi @maahirafridii
2K Followers 2K Following зоолог /PTI Social media warrior/Civil Engineer/Construction Manager / Freelancer / Pashtun/Insafian / Travelerふぁんとむ🌙 @Phantom_kiseki
5K Followers 5K Following 呼び方は『ふぁんちゃん、でお願いします』 面白そうな人だなって思ったらフォローしてね✨おはポス1回、夜ポスト1回が基本スタイル✨ももこ先生と博衣こよりちゃんが好き✨相互100@FB💯 @restaurant1031
4K Followers 4K Following 2024/01/21外国人のフリするとフォローバックされない⁇実験終了。拡散アカに転生するかぁ。もう一度フォロー申請するけど気付かないだろうなぁ。皆さん。Jimbo @JimGagnon6
38K Followers 27K Following Son of the King, Protagonist, Trump Supporter, Husband, Father, Grandfather #ImpeachRINOs #MAGA #KAG #1A #2Aمتابعة @__6cv
538K Followers 465K Following ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀ いつも日本の平和を守っていただきありがとうございます(^_^)/それ 💞💞では本題の好 ふぉろーありがーとっ ふぉろばするねっ! ⠀ ⠀ ⠀⠀ٍFermata神戸三宮�.. @fermata4649
6K Followers 5K Following 神戸三宮にあるリラクゼーションサロンFermataです。厳選された美女達がお出迎え致します。ご予約、ご来店心よりお待ち致しております。#三宮メンズエステ #神戸メンズエステ #リラクゼーションサロン #プライベートサロン💀𝕏._.🅳🅰�.. @DanyalSharif_0
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61K Followers 62K Following US Army retired, originally from NW PA, living on the West Coast. Knowledge is Power. God Bless America. One Nation Under God. PATRIOT.......IFBAPDaily Observer @Dailyobserve
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15K Followers 16K Following كاتب وتربوي واعلامي سابق رد المتابعة مضمون غزة عزتنا وكرامتنا في زمن الخنوع لكل من يمقت حربائية الرؤى لكل من يتشح بلون الكرامة في زمن السقوطイタリア街路樹.. @xxtaketomyxx
101K Followers 90K Following **⃝¨*•YouTube.•**⃝ https://t.co/VSNMSCSn4r **⃝¨*•TikTok.•**⃝ https://t.co/BPUXfNz0Xe ヨーロッパをお届け!! 日常から世界遺産まで時折✨Live✨ ⛔NO DM⛔ FollowBack💯Adria Pagel @AdriaP16309
65 Followers 5K FollowingTHINK UNLIMITED @shw490490
935 Followers 1K Following FOLLOW FOR FOLLOW BACK 🔙💯. Inspiring curiosity. Welcome to Think Unlimited! Join us on a thought-provoking journey as we challenge norms and explore endlessShahwar Hassan Waraic.. @WaraichShahwar
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4K Followers 8K Following 私は、絵描きを、、めざしています。54の、オッサンです。きにいってくれましたら、フォロー、お願いします。#イラスト#イラストレーター#絵描き I am aiming to become a painter. I'm a 54 year old man. If you go, please follow me.Tech Informer.org @TechInformerOrg
465 Followers 2K Following Dive into the latest tech breakthroughs, trends, from quantum leaps to AI advancements. ~ Follow us for the latest tech news🔔Ayesha Yousafzai PTI @AKY804
3K Followers 6K Following MS Student of Biomedical Sciences at University of Copenhagen DenmarkWanda @wanda92corvino
203 Followers 3K FollowingChristopher Antoniou @ChristosA89
325 Followers 448 Following NATURE LOVER I explore Colne Valley Regional Park's biodiversity SCROLL DOWN FOR WILDLIFE I DOCUMENTMarie @marie_curtis_
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15K Followers 14K Following 🇺🇸 Conservative #MAGA patriot and AI artist! Followed by @catturd2 🇺🇸 Sharing my views with a little satire 🦅 My pronouns are: UN/VAC/CI/NAT/ED 💉Collectibulldogs @collectibulldog
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3K Followers 2K Following Scientist, engineer, professor, inventor of 36 issued patents, conservative, duckSun♒ @aftabkayani85
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65K Followers 774 Following Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)Carolyn Bertozzi @CarolynBertozzi
77K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈Prof. Akiko Iwasaki @VirusesImmunity
220K Followers 2K Following We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAIScientist to Founder @sci2founder
3K Followers 10 Following Empowering talent to build enduring businesses. Powered by @axialxyzBioBuilders Jobs Boar.. @BioBuilderJobs
1K Followers 10 Following An ecosystem for scientists, inventors, engineers, executives, and operators to find new opportunities and jobs. Powered by @axialxyzStandard Biology @StandardBiology
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3K Followers 10 Following Open sourcing information to activate more talent in science. Powered by @axialxyzDNA Tie Club @dnatieclub
6K Followers 10 Following Shining light on great inventors and founders. Powered by @axialxyzJoshua Elkington @elkingtonxy
25K Followers 4K Following Founder and General Partner at Axial @axialxyzSoil microbiota transplanted from more stressful environmental conditions, such as drought or excessive heat or cold, can enhance tree tolerance to changing climates, researchers reported last year in Science. Learn more on #ArborDay: scim.ag/6K5
Happy to share the final version of our work describing computational filters for selecting functional ML-generated enzymes in @NatureBiotech! This was a distributed and remote collab with @TrichomeDoctor @Xiaozhi_Fu and other members of @AZelezniak's group. Global Science!
Our computational filter for enriching functional AI-generated enzymes is finally out. nature.com/articles/s4158… Many thanks to @TrichomeDoctor @KevinKaichuang @Xiaozhi_Fu et al. for the fantastic collaboration!
In Science, researchers present a strong, heat-resistant plastic completely derivable from renewable plant material that can be easily broken down in methanol. Learn more: scim.ag/6G1
Features derived from AF2 structures can predict in-vivo protein properties and phylogenetics. @mjstam @doyarzunrod @nadanai263 @ChrisWellsWood biorxiv.org/content/10.110…
That's my designed protein on the cover of Science! Achievement unlocked!
Researchers in Science present a next-generation protein structure prediction and design tool, #RoseTTAFold All-Atom, that can accept a wide range of ligands and covalent amino acid modifications. Learn more in this week's issue: scim.ag/6Ea
Nature research paper: Machine learning reveals the control mechanics of an insect wing hinge go.nature.com/4atT0DD
In a new @SciImmunology Review, scientists discuss how resident tissue #macrophages go beyond immunity to keep organs thriving. scim.ag/6Cv
A pioneering ‘connectomics’ collaboration has successfully reconstructed one cubic millimetre of brain tissue, but researchers are still just scratching the surface of the complexity it contains go.nature.com/3Q4sSH8
Detection, regulation, and functions of RNA N6-methyladenosine modification in plants hubs.li/Q02s3qTB0 #PlantCommunications highlight @MPlantPCom
Directed Evolution of Antibodies with Doug Chapnick @ChapnickDoug Excited to have a conversation with Doug, the Co-Founder & CEO of BioLoomics @bioloomics. A platform company using directed evolution to discover antibody therapeutics. Combining synbio, ML, and imaging
Transforming biomanufacturing using software with Martin Permin @purrmin Excited to have a conversation with Martin Permin, Founder and CEO of Invert. The company is on a mission to transform biomanufacturing through advanced software and data analytics
Viruses living in the gut could play a role in regulating stress, according to a mouse model study published in @NatureMicrobiol. go.nature.com/3wmOxU6
This paper is wild! Mutations in CRB1 cause retinal degeneration that lead to vision loss. CRB1 is expressed in the retina and studies have focused on its role in retinal cell proliferation, cell-cell junctions, adhesion, and endosome recycling /1
Now online! CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut dlvr.it/T3HNMM
What’s the best & lowest cost way for a startup to file patent?
Which biobanks are the easiest to work with?
The work heralded @Nature as ‘On the genetic basis of tail-loss evolution in humans’ nature.com/articles/s4158… has a number of issues that question the headline and make the conclusion misleading 1/n
Exciting new work from Nathanael Gray’s lab @Stanford_ChEMH published @ACSCentSci, covalent inhibitors with two electrophilic warheads subvert resistance due to single mutations in kinase targets pubs.acs.org/doi/10.1021/ac…
Which companies are developing oral biologics?
I don't get paid by @BioRender, but I am so excited about the biorender + powerpoint joint. We can now update our biorender images in powerpoint with just one click, no more exporting, copying and pasting 🔄
Let the Best Drug Win with Errik Anderson youtu.be/lZl9GwhOyYs Errik is the CEO and Founder of Alloy Therapeutics. Founded in 2017, Alloy democratizes access to drug discovery platforms and services. In our conversation, we discuss Alloy's product offering and story