Michael Eadon @EadonLab
Joined February 2021-
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@NIDDKgov @NatureComms @KPMProject Great to see this work in print. Thanks to the NIDDK and KPMP for their support. @WUNephrology @IUKidney @AshkarLab
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@NephJC So in this study both adaptive and maladaptive go under an umbrella. Other labs refer to these cell states as successful or failed repair.
@NephJC A lot of people find the adaptive maladaptive thing confusing. The essential part is that when cells start down an injury path (like epithelial to mesenchymal transition), it is unclear if their repair will succeed or fail.
Michael Eadon retweeted
Kudos to @ricmelof ….
Michael Eadon retweeted
🆕Clinical, histopathologic & molecular features of idiopathic & diabetic nodular mesangial sclerosis in humans 📸An example of ING (A) & diabetic glomerulosclerosis (B) on periodic acid–Schiff staining of paraffin-embedded sections are given ➡️ow.ly/zGdz50Ds09h @KPMProject
Check our latest work deconvoluting the renal interstitial gene signature. @ScienceAdvances @KPMProject
Very excited to share this work just out in Science Advances form the @KPMProject , that uncovers the molecular signature of the kidney interstitium (the "dark matter"). Molecular characterization of the human kidney interstitium in health and disease advances.sciencemag.org/content/7/7/ea…
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