Cornerstone Medical Education @Cornerstone_CME
Transforming clinician performance. Optimizing patient outcomes. One educational activity at a time. Joined May 2023-
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Out in @JCO_ASCO NECTIN4 Amplification predicts Enfortumab Vedotin response in Urothelial Cancer #mUC 💊 96% response rate to EV therapy in amplified cases vs 32% in others (P < .001). ➡️Perhaps we need to look deeper than IHC for other ADCs too? 🤔 ascopubs.org/doi/full/10.12…
How have HF mortality rates changed from 1999-2021 in the US? From 1999-2012 ↘ : Decline by ~25% From 2012-2021 ↗ Reversals that have now undone ALL initial declines. 🚨HF mortality in 2021 > HF mortality in 1999 🚨 jamanetwork.com/journals/jamac… @FudimMarat @ASayedMD @HFSA
Original Article: Exagamglogene Autotemcel for Severe Sickle Cell Disease (CLIMB SCD-121) nej.md/3UvzPDT Editorial: Extending Gene Medicines to All in Need nej.md/3QjCLAS #Hematology
🔴 Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review sciencedirect.com/science/articl… #cardiotwitter #CardioEd #CAAKI #Epeeps #cardiotwitter #EHRA2024 #CardioEd #Cardiology #FOAMed #MedEd #MedEd #Cardiology #cardiotwitter #cardiotwitter #cardiotwiteros
🚨Stunning!🚨 REVERSAL in the decline of heart failure ☠️ in the US 1999-2021 1999-2005 ⬇️ ☠️ 2005-2012 ⬇️ ☠️ 2012-2019 ⬆️ ☠️ 2019-2021 ⬆️⬆️☠️ Age-adjusted HF related ☠️ rates higher in 2021 vs 1999! WT😱🆘 jamanetwork.com/journals/jamac… @JAMACardio @FudimMarat
Contemporary American and European heart failure guidelines jacc.org/doi/abs/10.101… @JACCJournals
#BalanceDHF Milestone❗️ First pts enrolled in #BalanceDHF RCT studying unique #MRmodulator balcinrenone in combo w #SGLT2i dapagliflozin Seeking to expand therapeutic options in HF+CKD across the full spectrum of LVEF! Long way to go, but 💪🏾 global team classic.clinicaltrials.gov/ct2/show/NCT06…
FDA granted accelerated approval to tovorafenib for patients with relapsed or refractory BRAF-altered pediatric low-grade glioma. fda.gov/drugs/resource… #OCENewsBurst
⭐️Antibody-drug conjugates in lung and breast cancer: Current evidence and future directions – a position statement from the ETOP IBCSG Partners Foundation - Annals of Oncology annalsofoncology.org/article/S0923-…
Out in @JCO_ASCO: Results from Tropion pan-tumor 01. In patients with advanced HR+ BC and TNBC, Dato-DXd (trop2 ADC) demonstrated promising clinical activity and a manageable safety profile. #bcsm @OncoAlert @ErikaHamilton9 Full text: ascopubs.org/doi/pdf/10.120…
Out in @JCO_ASCO: Results from Tropion pan-tumor 01. In patients with advanced HR+ BC and TNBC, Dato-DXd (trop2 ADC) demonstrated promising clinical activity and a manageable safety profile. #bcsm @OncoAlert @ErikaHamilton9 Full text: ascopubs.org/doi/pdf/10.120…
Do #SGLT2i have a role in #CardioOnc? This review article highlights the cardioprotective evidence and the anticancer potential of SGLT2i in cardio-oncology. bit.ly/4ccqRCd #JACCCardioOnc @Zordoky_Lab @MohamedDabour91 @MinaYGeorge13 @maryraphel22 @BlaesAnneMD
#BetaBlocker use in #HFpEF and #HFmrEF❓ In this month’s issue of #JACCHF, analysis of #DELIVER trial shows: ♥️ 4 out of 5 px were treated with #BB ♥️#BB use wasn't linked to #worseningHF or #CVdeath ♥️Benefits of #Dapagliflozin remained consistent regardless of #BB ➡️➡️…
FDA approves lutetium Lu 177 dotatate for pediatric patients 12 years and older with somatostatin receptor (SSTR)-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETS). fda.gov/drugs/resource… #OCENewsBurst
Rich pipeline of alternative approaches to safely block MR axis being investigated in heart & kidney disease 🔥 K+ lowering therapies 🔥 Nonsteroidal MRAs 🔥 MR modulators 🔥 Aldosterone synthase inhibitors 👀 this rapidly changing space—upcoming HF RCTs to likely report '24 👇🏾
Rich pipeline of alternative approaches to safely block MR axis being investigated in heart & kidney disease 🔥 K+ lowering therapies 🔥 Nonsteroidal MRAs 🔥 MR modulators 🔥 Aldosterone synthase inhibitors 👀 this rapidly changing space—upcoming HF RCTs to likely report '24 👇🏾 https://t.co/7I9fHriUJ1
.@JACCJournals reference pocket cards for contemporary global guideline recommendations for drugs & devices in HF across the LVEF spectrum.🗒️ jacc.org/doi/10.1016/j.…
Key clinical takeaway is that in contemporary breast cancer pathology, most ER-low (< 10%) tumors will require chemotherapy and endocrine therapy.
Key clinical takeaway is that in contemporary breast cancer pathology, most ER-low (< 10%) tumors will require chemotherapy and endocrine therapy.
⏳early registration for #ISA2024 ending soon. Virtual & in person, state of the art #amyloidosis Amyloidosis_ARC @AmyloidosisSupp @MayoAmyloid @BU_Amyloidosis @Amyloid_MUSC @MayoClinicCV @MKIttlesonMD @BrettSperryMD @MasriAhmadMD @maz_hanna cveducation.mayo.edu/store/internat…
🔴 The Therapy and Management of Heart Failure with Preserved Ejection Fraction: New Insights on Treatment #2024Review #openaccess cfrjournal.com/articles/thera… #CardioEd #CardioTwitter #cardiology
New report on the risk of radiation necrosis with concurrent ADCs + brain RT. Incidence of symptomatic radiation necrosis was 27% with concurrent vs. 11% with non-concurrent ADC/RT (p=0.014). Important to temporarily stop the ADC before pursuing brain RT. link.springer.com/article/10.100…
Stephani Parten @PartenStep32222
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Jena Barby @je_barb
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Pascal Meier,MD @DrPascalMeier
109K Followers 120K Following Cardiologist UK & CH - Editor-in-Chief @Open_HeartBMJ. News on #Cardiology #UkrainiansAreDyingWhileRepublicansAreLying #Ukraine #Ukranian
Nicky Zangl @NickyZangl42209
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Quinn Gallenstein @QGallenste37547
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Zordoky_Lab @Zordoky_Lab
255 Followers 321 Following The overall goal of the Zordoky lab is to prevent and/or reverse the cardiovascular complications of cancer treatment
Keshia Lave @KeshiaLave34643
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JTH @JTHjournal
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Kamala Carreker @CarrekerKa52152
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ᴄᴜʀᴛᴀɪɴ @ipadp59267421
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sourpuff @sourpuff270885
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Sheryl Wayne @sherylwayne154
196 Followers 7K Following GOD FIRST. FOREX ACCOUNT MANAGER 💻📊 EARN UP TO $50k WEEKLY 🔥 DM TO JOIN MY TRADING TEAM. BITCOIN IS THE FUTURE OF MONEY 💰 💯🚀
Irish Jacquemin @IrishJacquem
86 Followers 5K Following
Teisha Sailors @sail_teis
72 Followers 5K Following
C. Michael Gibson MD @CMichaelGibson
436K Followers 374K Following Non-Profit Founder/Leader | ❤️ Doc | Artist Scientist Educator | News Anchor https://t.co/7OIKCgMVAT | RT ≠ endorse | Disclaimer: https://t.co/bwmE2O3U5W
Keanu Reeves @keanuureeeves
245 Followers 7K Following PRIVATE PAGE. _ Actor, JW❤ musician, play guitar make sure you listen to our album somewhere between the power lines and palm trees ❤❤
Jesusgab @Jesusgab225013
60 Followers 116 Following I love kindness , I'm doctor breast cancer specialist & consultant
Anoof Peediyak.MD @anoofpp
153 Followers 1K Following Med Director ,Cheif Rheumatologist and Clinical immunologist @ dranoof'sRheumaCare,Sr Consultant Aster MIMS, Entrepreneur,foodie, Hotelier, loves travelling...
John P Erwin III MD F.. @HeartOTXHeartMD
38K Followers 29K Following #Husband #Father #BigPoppy #MayoClinic trained #Cardiologist. ✭ Highly Educated- seeking #Wisdom ✭ “A Cheerful #Heart is Good #Medicine “#Proverbs17:22 ✭🫀🏈
Albert Vilella @AlbertVilella
21K Followers 8K Following Next-Generation Sequencing, Single-Cell and Spatial Biology, Next-Generation Proteomics, Synthetic Biology, Compute Acceleration in Biotech.
Zordoky_Lab @Zordoky_Lab
255 Followers 321 Following The overall goal of the Zordoky lab is to prevent and/or reverse the cardiovascular complications of cancer treatment
Martha Grogan MD @MarthaGrogan1
5K Followers 1K Following Cardiologist at #MayoClinic, former junior #Musketeer. #amyloidosis and #echo. Tweets limited to medicine and #Xavier basketball: my own and not my employer’s.
JTH @JTHjournal
9K Followers 7K Following The official journal of the @ISTH. Twitter content edited by @DianvanderwalDr @thebenignclot
RPTH @RPTHjournal
11K Followers 6K Following Research and Practice in Thrombosis and Haemostasis (#RPTH). #OpenAccess journal of @ISTH. EiC @ProfMakris. Impact Factor 4.6
Penn Women in Cardiol.. @PennCVWomen
1K Followers 147 Following Women cardiologists' group at @PennCardiology • Advancing opportunities throughout #WIC careers
Katherine Creeper @KJClots
97 Followers 171 Following Haematologist. Lover of haemostasis, thrombosis and obstetrics. Ocean swimmer and amateur runner.
Corey Cutler @DrCCutler
3K Followers 367 Following Director, Stem Cell Transplant Program @DanaFarber Cancer Institute. President @ASTCT. Tweets are my own and not medical advice.
Duke Heart @DukeHeartCenter
4K Followers 133 Following Duke Heart Center collaborates with hospitals and health care providers across the globe to further the science and standards of cardiovascular care.
Cardinale B. Smith @cardismith
1K Followers 542 Following Medical oncologist, palliative medicine physician, health services researcher. Working to improve the quality of care for patients with cancer.
marianna fontana @dr_m_fontana
436 Followers 87 Following Proud Mum and Professor of Cardiology, University College London
Sharmila Dorbala @DorbalaSharmila
3K Followers 329 Following Cardiovascular imager, Professor of Radiology, Harvard Medical School. Past President American Society of Nuclear Cardiology 2020. #Amyloidosis
JAHA @JAHA_AHA
28K Followers 1K Following JAHA - Journal of the American Heart Association Tweets/RT are not medical advice. RT/follows do not imply endorsement.
Jill Feldman @jillfeldman4
8K Followers 4K Following Lung Cancer Patient and Advocate, Co-Founder @EGFRResisters, wife, mom of 4, #LCSM #lungcancer #HealthEquity #EndStigma #RockChalk
Erin D. Michos, M.D. @ErinMichos
31K Followers 10K Following Johns Hopkins, Cardiology. Co-Editor in Chief @AJPCardio. Director, #WomenHeartHealth. #Menopause #INOCA #CardioObstetrics #SCAD #cvPrev #lipids #echofirst.
Aditya Bardia, MD @dradityabardia
3K Followers 123 Following Medical Oncologist, UCLA. Passionate about accelerating innovative research and fostering academic mentorship to improve patient outcomes.
Alfonso Valle @ValleAlfonso
21K Followers 153 Following Jefe Servicio Cardiología. Hospital Denia (Alicante). Cardiólogo Hospital La Salud (Valencia)
Rajiv Agarwal MD, MS @AgarwalRajivMD
2K Followers 408 Following Kidney doc in Indiana. Also a clinical trialist, journal editor, biostatistician, photographer, and traveler.
Mazen Hanna @MazenHannaMD
93 Followers 12 Following Cardiology at Cleveland Clinic, opinions are my own
Stephen Heitner @HeitnerStephen
597 Followers 361 Following Passionate about treating (and curing) #HFrEF #HFpEF #HCM and #AMYLOIDOSIS. Research is the path forward. Opinions are my own entirely.
Azita Talasaz @AzitaTalasaz
270 Followers 212 Following Cardiology Pharmacist, PharmD, BCPS, BCCP, FCCP, FACC
Stephen V Liu, MD @StephenVLiu
24K Followers 3K Following Director of Thoracic Oncology & Developmental Therapeutics @Georgetown @LombardiCancer; Host @IASLC Podcast; Chair #DCLung24 #TexasLung24 #HereWeGo
Tara Lech PharmD, CAC.. @AnticoagPharmD
781 Followers 677 Following Systems Director of Anticoagulation Services, Beth Israel Lahey Health. NATF Medical Advisory Board & AC Forum ACE committee. Mom of 3 🧘🏻♀️Tweets are my own
Deborah Siegal @DebSiegal
2K Followers 1K Following Hematologist, Thrombosis doc and researcher @OttawaHospital @OttawasDofM @uottawa @canvector @thrombosiscan @AnticoagForum (she | her)
Infinite Strength @InfiniteMBC
408 Followers 254 Following Providing financial and emotional support to unserved single mothers living with MBC #lendyourstrength
Roberta Lombardi @Robertalom3
712 Followers 472 Following Founder of Infinite Strength, a nonprofit which provides recurring monthly funding to underserved single mothers with MBC. #lendyourstrength
Dr. Bishoy M. Faltas @FaltasLab
7K Followers 7K Following Physician-Scientist. Chief Research Officer @EngIPM. Gellert-John P. Leonard Scholar, Associate Professor @WeillCornell. Husband & father. RTs ≠ endorsements
Akl Fahed @aklfahed
2K Followers 3K Following Physician-scientist, Interventional Cardiologist @MGHMedicine @HarvardMed @BroadInstitute | genomics, coronary artery disease, healthcare innovation
Albert Vilella @AlbertVilella
21K Followers 8K Following Next-Generation Sequencing, Single-Cell and Spatial Biology, Next-Generation Proteomics, Synthetic Biology, Compute Acceleration in Biotech.
Niklas Klümper @niklas_kluemper
1K Followers 3K Following Uro-Oncologist, Interested in precision oncology for ADC! NECTIN4 in met.UC? 🎯 Clinician Scientist and PI @IEO_HolzelLab @UniklinikBonn Tweets are my own
Rana McKay @DrRanaMcKay
4K Followers 791 Following GU medical oncologist @UCSanDiego, mom, wife, avid runner. Kidney and prostate cancer research. Tweets are my own and not medical advice.
Sek Kathiresan MD @skathire
30K Followers 989 Following CEO @VerveTx $VERV; Imagine if a one-time treatment led to permanent lowering of LDL cholesterol: that’s what we are developing to treat heart attack
Thomas Flaig @TomFlaigMD
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UroToday.com @urotoday
26K Followers 6K Following Largest global online community of #urological medical professionals & patients. #bladdercancer #menshealth #prostatecancer #kidneycancer #Urology
Dr. Patrick Hwu @PatrickHwuMD
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Sunny Varshney, MD @SunnyVMD
2K Followers 2K Following Heart Failure, Cardiac Transplant, and Mechanical Support @Stanford_HF | Venture Advisor @ Broadview Ventures | Tweets/views my own
University of Kentuck.. @UKYurology
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Patrick Hensley, MD @pjhensley11
336 Followers 215 Following Urologic Oncologist at the University of Kentucky. Bladder cancer researcher. Husband and father x3.
JAMA Cardiology @JAMACardio
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Dr. Purvi Parwani @purviparwani
36K Followers 2K Following Cardiologist, Associate Prof of medicine , Director echo lab MMI #LLUH, tweets=myopinion #ACCImaging #whyCMR #Echofirst #YesCCT #WomenCVhealth🧘♀️ 🌱 🇮🇳 🇺🇸
Kiran Khush @KiranKhush1
2K Followers 334 Following Professor, Heart Failure Transplant Cardiologist at Stanford, clinical and translational investigator, Mom of 3 great kids, tweets are my own.
Anu Lala-Trindade @dranulala
11K Followers 5K Following Mother/wife/daughter. 💜Function cardiologist. Deputy Editor @JCardFail. HF Fellowship PD @MountSinaiNYC; DCC for @NHLBI CTSN; pursuing #SelfAwareness
Jason N. Katz @JasonKatzMD
8K Followers 3K Following NYU Cardiology, Associate Chief at Bellevue, Adv HF/Transplant PD, VAD Associate Director - Cardiovascular Critical Care - views my own, RT not endorsement
Rachna Kataria, MD @rachkataria
3K Followers 866 Following Asst Prof @BrownMedicine |Advanced Cardiomyopathy @RIHospital @TuftsMedicalCtr|Alum @MGHHeartHealth @MonteHeart| tMCS, #cardiogenicshock|RT≠endorsement|she/her
Eiran Gorodeski, MD, .. @EiranGorodeski
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Alexander Hajduczok, .. @AHajduczok
9K Followers 5K Following @TJHeartFellows Cards Fellow PGY-6 | Future @UCSDCardiology Adv HF Fellow | Remote Monitoring, Hemodynamics | @whoop | @JCardFail FIT editor | Go Bills
Srihari S. Naidu, MD @SrihariNaiduMD
10K Followers 2K Following Prof of Med (H39); Interv Card & HCM; Dir CCL; Brown U Trustee Emer; SCAI VP; NY ACC Pres; ACC BOG; NYS CAC; Comic Art Collector; Knicks fan; tweets=my opinionOut in @JCO_ASCO NECTIN4 Amplification predicts Enfortumab Vedotin response in Urothelial Cancer #mUC 💊 96% response rate to EV therapy in amplified cases vs 32% in others (P < .001). ➡️Perhaps we need to look deeper than IHC for other ADCs too? 🤔 ascopubs.org/doi/full/10.12…
How have HF mortality rates changed from 1999-2021 in the US? From 1999-2012 ↘ : Decline by ~25% From 2012-2021 ↗ Reversals that have now undone ALL initial declines. 🚨HF mortality in 2021 > HF mortality in 1999 🚨 jamanetwork.com/journals/jamac… @FudimMarat @ASayedMD @HFSA
Original Article: Exagamglogene Autotemcel for Severe Sickle Cell Disease (CLIMB SCD-121) nej.md/3UvzPDT Editorial: Extending Gene Medicines to All in Need nej.md/3QjCLAS #Hematology
How exercise promotes a healthy immune response, reduces inflammation, and may slow the aging process cell.com/cell-metabolis… @Cell_Metabolism @KentLangston
MYK-224 for #HFpEF Developed originally for #HCM Whether there will be further development in #HCM or not is unclear #CardioTwitter
🔴 Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review sciencedirect.com/science/articl… #cardiotwitter #CardioEd #CAAKI #Epeeps #cardiotwitter #EHRA2024 #CardioEd #Cardiology #FOAMed #MedEd #MedEd #Cardiology #cardiotwitter #cardiotwitter #cardiotwiteros
Looking forward to seeing the detailed #SEQUOIA trial results - aficamten in obstructive #HCM at #ESC #HFA2024
We're pleased to announce 3 late-breakers at the European Society of Cardiology's Heart Failure 2024 Congress including the primary results from SEQUOIA-HCM. #HeartFailure2024 #HCM bit.ly/3UyyGeM
🚨Stunning!🚨 REVERSAL in the decline of heart failure ☠️ in the US 1999-2021 1999-2005 ⬇️ ☠️ 2005-2012 ⬇️ ☠️ 2012-2019 ⬆️ ☠️ 2019-2021 ⬆️⬆️☠️ Age-adjusted HF related ☠️ rates higher in 2021 vs 1999! WT😱🆘 jamanetwork.com/journals/jamac… @JAMACardio @FudimMarat
Excited to share our publication of T-DXd vs. T-DM1 in pts with brain 🧠 mets from DB-03. ⭐️ PFS 15 months w/T-DXd vs. 3 months w/ T-DM1 Trastuzumab deruxtecan vs trastuzumab emtansine in brain metastases in DESTINY-Breast03 trial - ESMO Open esmoopen.com/article/S2059-…
Contemporary American and European heart failure guidelines jacc.org/doi/abs/10.101… @JACCJournals
Want to learn more about access to lipid lowering therapies in very high risk ASCVD, click the link the link for a session I moderated: pharmacytimes.com/peer-exchange/… @PharmacyTimesCE @UK_COP @accpcardprn @ACCinTouch #ACCCVT @AHAScience
#BalanceDHF Milestone❗️ First pts enrolled in #BalanceDHF RCT studying unique #MRmodulator balcinrenone in combo w #SGLT2i dapagliflozin Seeking to expand therapeutic options in HF+CKD across the full spectrum of LVEF! Long way to go, but 💪🏾 global team classic.clinicaltrials.gov/ct2/show/NCT06…
Impressive intracranial activity of both T-DXd (65%) and T-DM1 (34%) for HER2+ brain metastases. 🎙️ Don’t miss the accompanying podcast, where @curijoey and I had the opportunity to interview Sara Hurvitz and @nlinmd to discuss the results. Spotify Link: open.spotify.com/episode/2JO8wQ…
Out in @ESMO_Open the intracranial activity of T-DXd vs T-DM1 in the DESTINY-Breast03 phase 3 trial. Among patients with active brain mets, IC-ORR was 65.7% with T-DXd vs 34.3% with T-DM1. Accompanied by a podcast 🎙️ & an editorial by @drsarahsam @nlinmd. esmoopen.com/article/S2059-…
FDA granted accelerated approval to tovorafenib for patients with relapsed or refractory BRAF-altered pediatric low-grade glioma. fda.gov/drugs/resource… #OCENewsBurst
We're proud to make @JCardFail the home for this important work! @robmentz @dranulala @AndrewJSauer @DrMarthaGulati @jilliannec @QuentinYoumans @AshishCorrea @beaverspharmd @vbluml @heartofthemater @HFSA
Excited to share our paper exploring successes and opportunities for growth in #palliativecare education in #cardiology fellowships. Grateful for the thoughtful contributions of our all-star team! @SarahChuzi @DrDamluji @haiderwarraich @Gwen_Bernacki @steiner_md
⭐️Antibody-drug conjugates in lung and breast cancer: Current evidence and future directions – a position statement from the ETOP IBCSG Partners Foundation - Annals of Oncology annalsofoncology.org/article/S0923-…
Out in @JCO_ASCO: Results from Tropion pan-tumor 01. In patients with advanced HR+ BC and TNBC, Dato-DXd (trop2 ADC) demonstrated promising clinical activity and a manageable safety profile. #bcsm @OncoAlert @ErikaHamilton9 Full text: ascopubs.org/doi/pdf/10.120…
The rising wave of DXd-charged anybody-drug conjugates 🌊 #DESTINY01 #TROPION01
Contemporary American and European Guidelines for Heart Failure Management: #JACC: #HeartFailure Guideline Comparison @ACCinTouch @escardio @mvaduganathan @BiykemB jacc.org/doi/full/10.10…
.@JACCJournals reference pocket cards for contemporary global guideline recommendations for drugs & devices in HF across the LVEF spectrum.🗒️ jacc.org/doi/10.1016/j.…
Do #SGLT2i have a role in #CardioOnc? This review article highlights the cardioprotective evidence and the anticancer potential of SGLT2i in cardio-oncology. bit.ly/4ccqRCd #JACCCardioOnc @Zordoky_Lab @MohamedDabour91 @MinaYGeorge13 @maryraphel22 @BlaesAnneMD
👏🏽👏🏽👏🏽 @MattFeinsteinMD - important opportunity to better define the role of inflammation in #CVD @AHAScience @American_Heart @NUFeinbergMed @NMCardioVasc @HFpEF
🙏 to @AHAScience @American_Heart @NUFeinbergMed @NMCardioVasc & collab w/ @CSUPharmacy. Excited for the work ahead w/ @thorplab @HFpEF Kiarri Kershaw Bill Grobman @MCarnethon @dmljmd @SusanQuaggin @NMHheartdoc @KeybrdBiologist @HeartDocSadiya @RBPatelMD @ShainaAlxndria & more!
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