Circulation: Genomic and Precision Medicine @Circ_Gen
We seek studies in genomics and precision medicine with relevance to human CV biology. RT/follows do not imply endorsement ahajournals.org/journal/circgen Joined November 2017-
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As part of our #cardioinformatics series: @IrisJaffeLab + team: Development and Implementation of an Integrated Preclinical Atherosclerosis Database ahajournals.org/doi/10.1161/CI… @AHAScience #AHAjournals #CardioTwitter #Genetics 📽️@hj_tadros
From Souter + Benn + team: Reproductive Carrier Screening: Identifying Families at Risk for Familial Hypercholesterolemia in the United States ahajournals.org/doi/10.1161/CI… @AHAScience #AHAjournals #CardioTwitter #Genetics @NateraGenetics 📽️@hj_tadros
From Krysov + @vnparikh + team: Regional Variation in Cardiovascular Genes Enables a Tractable Genome Editing Strategy ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics @euanashley 📽️@hj_tadros
Curious about JAHA? Come meet Associate Editor Tiffany Powell-Wiley at #EPILifestyle24! Tuesday, March 19, from 5-6pm CDT at the Hilton Chicago (Room: Astoria, 3rd floor). We'll see you there! #ahajournals
🔴 Imagenetics for Precision Medicine in Dilated Cardiomyopathy @CircAHA #CardioEd #Cardiology
📰Check out our latest paper about RRAGD, a new gene to consider in DCM with AD inheritance🧬 @Circ_Gen @hbellvitge
I think the field needs more of these kinds of studies - canvassing the impact of many variants, many previously unknown, to determine the influence on heritable CV disease. @Circ_Gen @AHAScience #HCM @4hcm #CardioTwitter
From Ravi Shah + @ryden_mikael + @venkmurthy + team: Targeted proteomics reveals functional targets for early diabetes susceptibility in young adults ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics 📽️@hj_tadros 🎙️@AnwarChahal @SharafGhaith
From @COpbergen @MarioDelmar3 @marina_cerrone + team: AAV-Mediated Delivery of PKP2a Arrests Progression of ARVC in Murine Hearts: Preclinical Evidence Supporting Gene Therapy in Humans ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics 📽️@hj_tadros
Very proud to see our paper on #genetherapy in #PKP2 #ARVC online @Circ_Gen. A great collaboration and new hopes for #arrhythmias and #cardiomyopathy. @MarioDelmar3 @COpbergen @nyulangone @NYULHCVRC @nyugrossman
From Hasbani + de Vries+ team: Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis ahajournals.org/doi/10.1161/CI… @AHAScience #AHAjournals #CardioTwitter #Genetics @VibhuParcha
A/Prof Jodie Ingles @jodieingles27
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Michael J. Ackerman M.. @MJAckermanMDPhD
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Victoria Parikh, MD @vnparikh
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Ahmad Masri @MasriAhmadMD
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Andrew Landstrom, MD,.. @APLandstrom
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Emanuele Monda @MondaEmanuele
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John Giacona, PhD, PA.. @GiaconaJohn
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Marianna Daibes, MD @mariannadaibes
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janna @jan_nahlinke
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Santosh Mohan @theycallmeMohan
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A/Prof Jodie Ingles @jodieingles27
8K Followers 3K Following Head, Clinical Genomics Lab | Program Director, Genomics & Inherited Disease @GarvanInstitute | Cardiac Genetic Counsellor | Swiftie | Opinions my own
Pradeep Natarajan @pnatarajanmd
23K Followers 819 Following Dir of Preventive Cardiology @MassGeneralNews | Assoc Dir of Personalized Medicine @MassGenBrigham | Assoc Prof @harvardmed | Assoc Mem @broadinstitute
Michael J. Ackerman M.. @MJAckermanMDPhD
7K Followers 950 Following Mayo Clinic Genetic Cardiologist; Love taking care of families w/ #genetic #heart #diseases like #LQTS, #CPVT, & #HCM & researching their conditions.
Victoria Parikh, MD @vnparikh
2K Followers 606 Following Director, Stanford Center for Inherited Cardiovascular Disease (#SCICD). Study translational genetics in the lab to bring better therapies to our patients.
JACC Journals @JACCJournals
105K Followers 1K Following Official account representing the ACC's #JACCJournals, one of the most widely read & most impactful CV journal programs in the world. @ACCinTouch #JACC
Ahmad Masri @MasriAhmadMD
8K Followers 1K Following @OHSUCardio | #HCM #Amyloid #Fabry #LVH #Cardiomyopathies #Cardiogenetics #Echofirst #WhyCMR #CVNuc #RCTs | Views are mine & not medical advice
Silvia Castelletti @SilCastelletti
8K Followers 3K Following Cardiology - #EAPC_ESC #sports cardiology chair-elect - #genetic & #whyCMR- @escardio & @esc_journals SoMe Editor - #EJPC #EHJCR @Open_HeartBMJ Editorial Board
Andrew Landstrom, MD,.. @APLandstrom
1K Followers 411 Following Pediatrician, cardiologist, scientist, giant nerd passionate about caring for children with heritable arrhythmias & cardiomyopathies. Tweets are my own
MarkELindsay @MarkELindsay
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euan ashley @euanashley
6K Followers 749 Following Stanford Associate Dean | Author of The Genome Odyssey
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2K Followers 356 Following Professor of Cardiovascular Medicine, Consultant Cardiologist and Electrophysiologist researching sudden death, genetics and genomics.
Adam Butterworth @aidanbutty
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American Heart Associ.. @American_Heart
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10K Followers 2K Following Prof of Med (H39); Interv Card & HCM; Dir CCL; Brown U Trustee Emer; SCAI VP; NY ACC Pres; ACC BOG; NYS CAC; Comic Art Collector; Knicks fan; tweets=my opinion
John Giudicessi MD, P.. @JohnGiudicessi
368 Followers 238 Following Physician | scientist | husband | father of two | genetic cardiologist @MayoClinic and @MayoClinicCV | tweets = my own
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Julie De Backer @judbacke
1K Followers 503 Following Genetic Cardiologist @uzgent @ugent | Interest in #ACHD and #Marfan | FESC @escardio
Luis Lopes @LuisRLopesDr
830 Followers 861 Following Consultant Cardiologist and Associate Professor - Inherited Cardiac Disease and Cardiac MRI- Barts Heart Centre/University College London
Yuanyuan Wu @YuanyuanWu124
76 Followers 170 Following Postdoc @UCSF former postdoc @UConn PhD @UCAS1978. Investigating immunology, genetics, metabolism, neuroscience. Lover of plants.🌻🌳🍀
Tom Hays @txhays
234 Followers 759 Following https://t.co/vymfdy0cP3 Assistant Prof at Columbia-NYP NICU, husband, father, friend. Studying genomic neonatology.
Cardiomyopathy Associ.. @cmaa_aust
127 Followers 707 Following Cardiomyopathy Association of Australia is a registered, voluntary, charitable organisation supporting people with all forms of cardiomyopathy & their families.
Rachel M Bond, MD @DrRachelMBond
3K Followers 2K Following •Board-Certified👩🏽⚕️Cardiologist🫀 •Dog Lover •Writer •Spokesperson •Women's Heart & Prevention Specialist •Pioneer & Course Director: @whvsymposium
Dr Jacinta Kalisch-Sm.. @jkalism
246 Followers 589 Following BHF-CRE Intermediate Transition Fellow Oxford IDRM. Developmental biologist. Heart and placental biologist. From Brisbane, Australia.
Karen Flores @kpflores28
492 Followers 743 Following AHFTC Fellow @DukeCardiology/@UTSW IM Residency/@UWMadison Grad/#boricua🇵🇷/Interested in HF and Transplant, cardiomyopathies, and health disparities.
Kate Huang @katehuang_
220 Followers 582 Following PhD student @UBC @HLIStPauls | stem cell-derived cardiomyocytes | coffee lover 🫀☕️🏳️🌈
Julia Karady @KaradyJ
202 Followers 443 Following MD PhD @Semmelweishu, MPH candidate @HarvardChanSPH, Instructor @harvardmed, CVimager @CIRC_MGH |🇭🇺
Josh Saef @jsaef1
467 Followers 2K Following #ACHD Doc @JDCHospital - Tweets/Retweets not endorsements, medical advice, or reflective of my employer
Sara Cherny (she/her) @Sara_Cherny
989 Followers 809 Following Cardiovascular Genetic Counselor & Asst Prof at Lurie Children's. Chicago denizen. All tweets are my own. She/her. BLM. Love is love. Abortion is healthcare.
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francesca graziani_FG @FGraziani_Grace
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420 Followers 105 Following NIH R01-funded researcher, Assistant Professor @Columbia, Harvard-trained cardiologist, specialized in hypertrophic cardiomyopathy. Alma mater: Univ. of Tokyo🏀
Kaycee Carbone @KayceeCarbone
275 Followers 510 Following General Pediatrics & Vascular Anomalies GC | MGH IHP Genetic Counseling ‘23 🧬 | former 🥎 player | she/her
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Stroke AHA/ASA @StrokeAHA_ASA
35K Followers 2K Following Stroke publishes peer-reviewed research on cerebral circulation and its diseases. Tweets/RT are not medical advice. RT/follows do not imply endorsement.
Brigham & Women's CV .. @BrighamFellows
4K Followers 514 Following Cardiovascular Disease Fellowship @BrighamWomens @harvardmed @MassGenBrigham
Linea Christine Truds.. @LineaChristine
32 Followers 85 Following PhD student in group of Cardiac Genetics at @BiomedUCPH, @uni_copenhagen 🧬🫀👩🏽💻
Robert Giugliano @rgiugliano
561 Followers 184 Following Physician, Cardiovascular Medicine Brigham and Women's Hospital, Professor Harvard Medical School
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BIDMC CVI @BidmcCvi
2K Followers 2K Following The CardioVascular Institute at BIDMC includes specialists in Cardiovascular Medicine, Cardiac Surgery, Vascular & Endovascular Surgery. RTs ≠ Endorsements
SADS Foundation @SADSFoundation
3K Followers 2K Following The SADS (Sudden Arrhythmia Death Syndromes) Foundation saves lives and supports families of children and young adults who are predisposed to sudden death.
@MTome @DrMaiteTome
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Jon Cunningham @JonWCunningham
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Robert Mentz, MD @robmentz
12K Followers 9K Following Editor-in-Chief @JCardFail | Chief of the HF Section @DukeHealth | Trialist @DCRInews | Father of 3
Cheyanne Bell @CheyanneMBell
56 Followers 311 Following Clinical Research Assistant in Cardiovascular Medicine | Biology & Genetics Student at Arizona State University 🧬👩🏽🔬 Psalm 23:4 | Boy Mom
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860 Followers 816 Following Physician-scientist interested in the Heart, Stem Cells, CRISPR, CHIP, and Cardio-oncology @cityofhope
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Hearts in Rhythm Orga.. @HeartsInRhythm
2K Followers 2K Following HiRO | cardiogenetics experts, researchers, genetic counsellors, nurses & families | improving detection & care of inherited arrhythmias & cardiomyopathies 🇨🇦
Dr Alex Butters @alexbutters25
338 Followers 385 Following Lab Manager, Clinical Genomics Laboratory @GarvanInstitute | MPH PhD | Health Disparities in Genetic Heart Disease and SCD
Vibhu Parcha @VibhuParcha
448 Followers 1K Following 'Every New Discovery is a Reminder that We are All Small and Stupid' 🫀Inherited Heart Diseases 🧬 | #SoMe Editor @Circ_Gen | @UABHeersink | RT≠Endorsment
Dan Quiat @dquiat
156 Followers 284 Following Physician Scientist and Pediatric Cardiologist | Formerly @BCH_HeartCenter @HMSGenetics @HarvardMed @TheBCRP @lab_olson @UTSWmstp
Kambiz Ghafourian @KG_heartfailure
736 Followers 510 Following HF & Transplant Cardiologist @NorthwesternMed @NMCardioVasc.
Tami Johnston @TamiJohnston_GC
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Dr. Jennifer Huffman @JennyGenetics
343 Followers 485 Following Director of Genomics Research, Center for Population Genomics. Boston VA. MVP. CVD & Blood Genetics. Canada ➡️ Edinburgh ➡️ Boston. Opinions are my own.
Sean Jurgens @JurgensSean
237 Followers 287 Following MD MSc | Enthusiast for population genetics, statistical genetics, and cardiovascular sciences 🧬🫀🧬 Amsterdam UMC & Broad Institute of MIT and Harvard
UAB CardioVascular Re.. @UAB_CCTRP
465 Followers 401 Following The UAB CCTRP aims to translate experimental knowledge and discoveries into an improved understanding of human physiology through patient-oriented research.
Amit Khera @dramitkhera
6K Followers 2K Following Professor and Director of Preventive Cardiology UT Southwestern Medical Center; Chair, AHA Committee on Scientific Sessions Programming; Past President ASPC
Don’t miss Drs. Jeffrey Towbin from @LeBonheurChild and Jeffrey Kim from @TexasChildrens for a debate on "Novel Forms of Cardiomyopathy with Overlapping Features" at the 6th International Conference on Pediatric Cardiomyopathy. Register now: pcmconf.org #CardioTwitter
Clinical Guideline for Preimplantation Genetic Testing in Inherited Cardiac Diseases @Circ_Gen ahajournals.org/doi/abs/10.116…
🔴 Imagenetics for Precision Medicine in Dilated Cardiomyopathy @CircAHA #CardioEd #Cardiology
Imaging is often the first view we are offered of a patient with cardiomyopathy. Using this critical diagnostic test to focus attention on specific genetic loci is important. Imagenetics! @Circ_Gen @AHAScience
📰Check out our latest paper about RRAGD, a new gene to consider in DCM with AD inheritance🧬 @Circ_Gen @hbellvitge
Evidence that the genetic ancestral background of #iPSCs, and the cardiac myocytes derived from them, is an important biological variable to take into consideration when using these cells as models for cardiac disease. Congrats to @Circ_Gen @marieguerraty @kiranmusunuru
I think the field needs more of these kinds of studies - canvassing the impact of many variants, many previously unknown, to determine the influence on heritable CV disease. @Circ_Gen @AHAScience #HCM @4hcm #CardioTwitter
@Circ_Gen @COpbergen @marina_cerrone @AHAScience @hj_tadros Awesome animation and summary!!!!
Extremely proud of this work, in collaboration with Rocket Pharma: preclinical, IND-enabling demonstration of gene replacement therapy in a model of PKP2 deficiency. Relevant to arrhythmogenic cardiomyopathy. Available in PubMed!! PMID: 38288614 And in: ahajournals.org/doi/10.1161/CI…
Very excited to see our latest paper on #genetherapy for #PKP2 #ARVC published in @Circ_Gen! 🫀🧬 Great collaboration with @RocketPharma! @marina_cerrone @NYULHCVRC @nyugrossman ahajournals.org/doi/10.1161/CI…
Extremely proud of this work, in collaboration with Rocket Pharma: preclinical, IND-enabling demonstration of gene replacement therapy in a model of PKP2 deficiency. Relevant to arrhythmogenic cardiomyopathy. Available in PubMed!! PMID: 38288614 And in: ahajournals.org/doi/10.1161/CI…
Very proud to see our paper on #genetherapy in #PKP2 #ARVC online @Circ_Gen. A great collaboration and new hopes for #arrhythmias and #cardiomyopathy. @MarioDelmar3 @COpbergen @nyulangone @NYULHCVRC @nyugrossman
Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy @Circ_Gen ahajournals.org/doi/10.1161/CI…
Human genetic study concludes that individuals of European or East Asian ancestry are anticipated to generally have similar ASCVD benefit from HMGCR or PCSK9 inhibition ahajournals.org/doi/abs/10.116… @Circ_Gen
1.1% of #patients w/ #cardiomyopathy received #germline #genetictesting despite >298K #patients being eligible per guidelines rec #universal testing. Of #patients w/ positive tests, >90% had actionable results. #access #germlinetesting #reducedisparitie #precisionmedicine…
From @AnaMoralesCGC + Murillo + team: Real-World Genetic Testing Utilization Among Patients With Cardiomyopathy ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics
Great work @AnaMoralesCGC. This is not news to those of us @SADSFoundation who talk w/patients every day but it is shocking and unacceptable in the care of people with cardiomyopathies.
From @AnaMoralesCGC + Murillo + team: Real-World Genetic Testing Utilization Among Patients With Cardiomyopathy ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics
Funding research is a cornerstone of the AHA’s lifesaving mission and a key to our future. We’re continually adding new programs for timely, mission-related cardiovascular and neurovascular research. See the latest opportunities at spr.ly/6014uKzIE
ATTRibute-CM trial: In patients with transthyretin amyloid cardiomyopathy, the receipt of acoramidis resulted in a significantly better four-step primary hierarchical outcome containing components of mortality, morbidity, and function than placebo. nej.md/48tEoTH
Out in @Circ_Gen: An excellent look at phenotype, outcomes, and response to therapy in patients with NEXN-encoded nexilin variants. Predominantly associated with DCM (infant onset disease of homozygous/compound heterozygous) with some developing HCM and sudden death @AHAScience
From @ahermidaj+ Ader + team: NEXN Gene in Cardiomyopathies and Sudden Cardiac Deaths: Prevalence, Phenotypic Expression, and Prognosis ahajournals.org/doi/abs/10.116… @AHAScience #AHAjournals #CardioTwitter #Genetics 📽️@hj_tadros 🎙️@AnwarChahal
Topline results #HCM #CardioTwitter
Amazing effort by patients, coordinators, PIs, sponsor et al. 282 patients with obstructive #HCM #aficamten vs #placebo Topline results tomorrow #CardioTwitter
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