ProBenC @BenIsWell
Joined October 2018-
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Hi @Nutritionwonk. Seen this study? Does saturated fat lack LDL dose-response? Was this reported or confirmed in other studies? And thanks.
@TheCuriousAhmed @Dr__Guess Interesting! @JPMcCarter @NutritionWonk @whsource @erik_arnesen @kcklatt @KevinH_PhD
@NigelKinbrum @janvyjidak @Gearoidmuar Interesting links- but fasting seemed to have the worst effect on glucose tolerance. I didn't see any of the links mentioned pancreas function- lmk if i missed something.
@Chrest_brett @whsource @shashiiyengar @garytaubes @JohnSpeakman4 "the effects on carotid plaque and vascular function" This was an epidemiology or RCT?
@whsource @AlquierThierry I take my words about you.
@whsource @cold_commute Sure, but the way you post this is pretty misleading.
@erik_arnesen @NutritionWonk The advice of eating lean red meat instead of high fat red meat might be extremely unwise for the prevention of chronic diseases and CVD.
@erik_arnesen @NutritionWonk In my opinion the data is very consistent, but there's little irony believing it's animal protein/lean rather than SFA is what causes the problems (some people may not accept this), but when you think about it everything starts to make sense.
@NutritionWonk @erik_arnesen In my previous comment “confounding with something else” I suggest: healthy user bias, processed meat or animal protein. But I'm not sure, it's confusing to me.
@NutritionWonk @erik_arnesen So it would be very plausible that fat from dairy associated with CVD, and fat from meat not, yet the opposite here in these studies.
@erik_arnesen @NutritionWonk What are your thoughts on this? Agreed with the conclusions (re: SFAs), or could be due to confounding with something else?
@e_geak @NutritionWonk @TamarHaspel @YoniFreedhoff @whsource @erik_arnesen @TheCuriousAhmed Here as I said before:
@whsource @erik_arnesen This study examined the effect of genetically high TG vs genetically high LDL, not genetically low TG vs genetically low LDL. This is newer, more recent study jamanetwork.com/journals/jamac… TG lowering via LPL alleles was as important, or even more important than LDL lowering.
@e_geak @NutritionWonk @TamarHaspel @YoniFreedhoff @whsource @erik_arnesen @TheCuriousAhmed This is because there's a corresponding differences in ApoB between lowering of LDL or TG or increasing of LDL or TG, as in this genetic study discussed earlier:
@NutritionWonk @TamarHaspel @YoniFreedhoff And also this recent study: acc.org/latest-in-card… The study measured CHD outcomes in 2 different genetic variants:
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